latest news: Pharmaceuticals
Showing 10 of 74 Articles:
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Osteoporosis Treatments Affect Bone Matrix Maturation in a Rat Model of Induced Cortical Remodeling.
Excerpt The example of sodium fluoride (NaF) clearly demonstrates an instance where increasing bone mass while altering maturation can negatively affect drug efficacy. NaF was a promising osteoporosis treatment because it increased BMD.5 However, it became evident that the treated patients were at increased risk of fracture,6, 7 which was later attributed to NaF-induced aberrant […]
Pharmaceuticals -
The Dark Side of Fluorine.
Full Text: ABSTRACT: Despite the perceived stability of the C?F bond, chemical instability and drug-metabolizing enzymes can lead to its cleavage. The resulting release of fluoride and formation of certain metabolites may cause safety issues and warrant the medicinal chemists’ attention. Fluorine is an indispensable tool in the medicinal chemists’ toolbox. Due to its small […]
International Pharmaceuticals -
[18F]Fluoride : molar activity and utility in radiosynthesis and in biological applications
A radiopharmaceutical is a radioactive isotope combined with a biologically interesting molecule that targets specific tissues, organs, or cells in the living body. This special class of medicinal product has applications in both diagnostics and therapy. Positron emission tomography (PET) is a powerful non-invasive imaging technique that utilises gamma rays generated by short-lived positron emitting […]
Finland Pharmaceuticals -
Chemical spill at lab sends 2 to hospital in Waltham
Two people were taken to the hospital Tuesday after a chemical spill at a Waltham lab, officials said. Police and firefighters rushed to 35 Gatehouse Drive after a minor release of hydrofluoric acid in one of the labs in the building around 9:53 a.m. The building is mostly occupied by Astrazeneca Pharmaceuticals, Waltham Fire Lieutenant […]
United States, Massachusetts Pharmaceuticals -
Researchers make discovery that will benefit pharmaceutical companies
UTSA [University of Texas at San Antoni0] Researchers, led by Dr. Aimin Liu, professor and luther brown distinguished chair in biochemistry, made a discovery regarding fluorine, a reactive – and often toxic – chemical element found in water and air, also used in toothpaste and medicine. Not much is known about fluorine, aside from its […]
United States, Texas Pharmaceuticals -
UTSA chemists make historic fluorine discovery
Note from the Fluoride Action Network – The articles we add to the NewsTracker have an importance that we want our readers to know about. Sometimes these articles contain misinformation, such as this one, and we wish to correct it. In the second paragraph the author states that fluorine is a “non-toxic element”. Fluorine is […]
Pharmaceuticals -
Synthesis of the veterinary antibiotic florfenicol by a fast chemo-enzymatic route
Fluorinated structures make up more than 20 percent of modern drugs, but benign and fast fluorination schemes are scarce. In a study published in the European Journal of Organic Chemistry, scientists have now combined dynamic kinetic resolution and nucleophilic fluorination for the asymmetric synthesis of florfenicol, a veterinary antibiotic. After enzymatic resolution of the racemate, […]
International Pharmaceuticals -
Tinci Materials to Use NEV Battery By-Products for Drugs, Pesticides
A unit of Tinci Materials Technology will seek uses for by-products that form while refining materials for new energy vehicles’ batteries. Jimute New Materials will construct production lines for by-products, such as photoinitiators, methyl acetate, trifluoroacetic acid, and sulfuryl fluoride, which appear while processing lithium hexafluorophosphate, the Guangzhou-based chemical manufacturer said in a statement yesterday. […]
China Batteries Pesticides Pharmaceuticals -
Cerecor Announces Expansion of Leadership Team
BALTIMORE, July 16, 2018 (GLOBE NEWSWIRE) — Cerecor Inc. CERC, +2.91% today announced executive management changes that continue the Company’s strategic shift and further align its organizational structure to its long-term strategy. Specifically, effective today, the Company announced the appointment of Joe Miller as Chief Financial Officer, Dr. Pericles Calias as Chief Scientific Officer and […]
United States, National USA Pharmaceuticals -
A New FDA Warning About Serious Fluoroquinolone Side Effects
We can hardly believe that once again the Food and Drug Administration is warning about fearsome complications from antibiotics like Cipro and Levaquin. Serious fluoroquinolone side effects have been a worry for decades. Despite that, we calculate that over 10 million prescriptions are dispensed annually for drugs like ciprofloxacin and levofloxacin. They were originally perceived […]
United States, National USA Pharmaceuticals