latest news: Pharmaceuticals
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Pre-validated fluorinated fragment library
The Maybridge Fluorine Labeled Fragment Library is a fragment library of 480 fluorinated compounds developed in collaboration with Argenta, a Charles River Company, the University of Kent and the United Kingdom’s Biotechnology and Biological Sciences Research Council. Approximately 20% of known drug compounds contain a fluorine atom. Read full article Print PDF
United Kingdom, England Pharmaceuticals -
How Fluoridated Antibiotics Can Damage Your Body
In August 2014, the FDA released a statement stating the dangers of fluoridated antibiotics and the effects of nerve damage on the body. All of the drug labels on these medications have been updated to better describe the serious side effect of peripheral neuropathy. According to this announcement, “The risk of peripheral neuropathy occurs only with […]
United States, National USA Pharmaceuticals -
Fluoroquinolones: The Deadliest Antibiotics on the Market?
Fluoroquinolones are among the most commonly prescribed class of antibiotics in the United States. Among the most well known is Cipro (made by Bayer), which became a household name during the anthrax scare that occurred shortly after 9/11. Levaquin is a close second. All antibiotics carry a risk of side effects, but the fluoroquinolones are […]
Pharmaceuticals -
Fluoride drops: Coral Springs drug maker settles antitrust concerns with FTC
Boca Pharmacal and Endo Health Solutions agreed to a settlement with the Federal Trade Commission concerning Endo’s acquisition of the generic drug maker. The FTC had said the acquisition would be anti-competitive in the generics product market. Both companies agreed to no longer market and distribute four generic multivitamin fluoride drops for children, and to […]
Pharmaceuticals -
Ask the Pharmacist: Is your medication making you sick?
Dear Pharmacist, You said that some drugs are related to fluoride and may cause hypothyroidism or other diseases of the reproductive tract. Which medications and why? — D.L., Fort Lauderdale, Fla. Shocking, I know! Some of the most popular medications in the world are “fluorinated,” meaning they were created using a backbone of fluoride — […]
United States, New York Pharmaceuticals -
Warning on Sodium Fluoride Tablets
Sodium fluoride chewable tablets is used for: Preventing cavities in children over 6 months old when the amount of fluoride in the water supply is too low. Sodium fluoride chewable tablets is a mineral and a non-cavity-promoting sweetener combination. The mineral works by strengthening the teeth and decreasing the effects of acid and bacteria on […]
Pharmaceuticals -
Sevoflurane: Use of Potable Water Gets Drugmaker a 483
FDA investigators observed employees at Piramal Critical Care’s Bethleham, Pa., plant using potable water in the manufacture of finished drugs, which resulted in a Form 483 [see below]. During the manufacture of inhalational anesthetic drugs isoflurane and sevoflurane, Piramal did not conduct testing for microbial contamination in the water supply, which was used to “clean […]
United States, Pennsylvania Pharmaceuticals -
Fluoroquinolone Antibiotics May Cause Permanent Nerve Damage
The US Food and Drug Administration (FDA) recently issued a warning that fluoroquinolone antibiotics, taken by mouth or injection, carry a risk for permanent peripheral neuropathy. The safety announcement states:1 “The U.S. Food and Drug Administration (FDA) has required the drug labels and Medication Guides for all fluoroquinolone antibacterial drugs be updated to better describe […]
Pharmaceuticals -
New method of incorporating fluoride into drugs
Synthetic biology is a science that aims to harness natural biological processes for other uses, such as in the manufacture of fuels and drugs. Now, synthetic biology researchers in the U.S. have developed a new method of incorporating the highly reactive fluoride into a wider range of molecules than was previously possible. Fluorine rarely occurs […]
Pharmaceuticals -
Purdue Researcher’s New ‘Tool for the Organic Chemist Toolbox’ Licensed to Sigma-Aldrich
A Purdue University researcher’s U.S. patent for a safer, easier and “greener” method to incorporate fluorine into organic compounds – a common step in materials processing, drug discovery and synthesis of agricultural treatments – has been licensed to a subsidiary of Sigma-Aldrich Corporation, a St. Louis-based life science and high technology company. David Colby, assistant […]
Pharmaceuticals