latest news: Pharmaceuticals
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Chatham CVS drugstore error leads to oversight agreement
CHATHAM – A national pharmaceutical retailer has agreed to better oversight procedures and a $650,000 contribution to the state’s prescription drug awareness program following a 2012 incident in which several New Jersey outlets, including one in Chatham, mistakenly mixed a cancer drug in with children’s flouride [sic] medication. The agreement was announced Monday by State […]
United States, New Jersey Pharmaceuticals -
Dr. Askew to lead Fluoropeutics™ program at SciFluor Life Sciences
CAMBRIDGE, Mass. — SciFluor Life Sciences, a drug discovery and development company harnessing the transformational power of fluorine to accelerate the development of innovative new therapeutics, announced that Ben C. Askew, Ph.D., has joined the company as vice president, research. In this newly created position, Dr. Askew will oversee the development and expansion of the […]
Pharmaceuticals -
Chemists crack fluoroform challenge
US scientists appear to have cracked a long-standing problem in organofluorine chemistry – how to find a simple and efficient way to use the low-cost and abundant compound fluoroform as a trifluoromethylation agent. The work opens the way to tap the large volumes of fluoroform, CF3H, which are by-products of the synthesis of materials such […]
Pharmaceuticals -
Fluoroform (CF3H): Researchers turn harmful greenhouse gas into a tool for making pharmaceuticals
A team of chemists at USC has developed a way to transform a hitherto useless ozone-destroying greenhouse gas that is the byproduct of Teflon manufacture and transform it into reagents for producing pharmaceuticals. The team will publish their discovery in a paper entitled “Taming of Fluoroform (CF3H): Direct Nucleophilic Trifluoromethylation of Si, B, S and […]
Pharmaceuticals -
Fluorination via porphyrin
The proposed mechanism relies on the oxomanganese to selectively cleave C-H bonds © Science/AAAS Despite fluorine’s popularity with medicinal chemists, reliable activation of aliphatic C–H bonds for fluorination has remained tantalisingly out of reach. Now, a manganese porphyrin has been used to selectively fluorinate sp3 carbon–hydrogen bonds using silver fluoride as a source of fluorine. […]
Pharmaceuticals -
WMIS Launches Clinical Trials for Sodium Fluoride (F-18) for CMS
With the success of the World Molecular Imaging Society’s (WMIS) initiative in helping obtain the FDA approval for Sodium Fluoride F18 injection, WMIS is now launching critical clinical trials to secure fair and meaningful reimbursement for this procedure. Successful clinical trials for reimbursement are necessary to ensure the feasibility and market acceptance for this diagnostic […]
Pharmaceuticals -
Voriconazole : Fluoride excess and periostitis in transplant patients receiving long-term voriconazole therapy
Full paper available online in html or pdf Abstract: Background. We describe a heart transplant patient with painful periostitis and exostoses who was receiving long-term therapy with voriconazole, which is a fluoride-containing medication. Elevated plasma and bone fluoride levels were identified. Discontinuation of voriconazole therapy led to improvement in pain and reduced fluoride and alkaline […]
Pharmaceuticals -
Some medicinal chemists can’t get enough fluorines in their molecules
Column: In the pipeline Some medicinal chemists can’t get enough fluorines in their molecules. Derek Lowe explains the love-hate relationship Fluorine is a nasty element. That may be an unfair judgment, but I’m prepared to defend it, at least as long as we’re talking about the zero-oxidation-state pure element. I have never used fluorine gas, […]
Pharmaceuticals -
Europe: SonoVue containing Sulphur hexafluoride, for use in ultrasound imaging
Excerpts: ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF THE MEDICINAL PRODUCT SonoVue 8 microlitres / ml powder and solvent for dispersion for injection 2. QUALITATIVE AND QUANTITATIVE COMPOSITION One ml contains 8 ?l of sulphur hexafluoride microbubbles On reconstitution as directed, 1 ml of the resulting dispersion contains 8 ?l sulphur hexafluoride in […]
Pharmaceuticals -
Bone Fractures: Symptoms or Side Effects?
Bone fractures are often a symptom of conditions or diseases such as osteoporosis, but could also be side effects associated with certain medications. Below is a list of diseases and conditions associated with symptoms like bone fractures, as well as a list of medications related to similar side effects. We are not medical professionals, and […]
Pharmaceuticals