Fluoride Action Network

Search

  • Further development of mathematical description for combined toxicity: A case study of lead–fluoride combination.

    Highlights Rats were exposed during 6 weeks to repeated i.p. injections of lead acetate, sodium fluoride or both in doses 0.05 LD50. The development of intoxication was estimated quantitatively with 54 functional, biochemical and morphometric indices. For mathematical description of effects a response surface regression model containing linear and cross terms was used. 10 types […]

  • Environmental Toxicity Assessment of Sodium Fluoride and Platinum-Derived Drugs Co-Exposure on Aquatic Organisms.

    1. Introduction Fluoride is used in the production of fluoridated dental products as well as it is used in drinking water fluoridation processes [1,2]. The World Health Organization establishes an acceptable level for drinking water, which ranges from 0.7 to 1.0 mg/L-1. However, fluoride concentrations of up to 20 mg have been recorded in some […]

  • Effect of Sodium Fluoride on Reproductive Function Through Regulating Reproductive Hormone Level and Circulating SIRT1 in Female Rats.

    References Kabir H, Gupta AK, Tripathy S (2020) Fluoride and human health: systematic appraisal of sources, exposures, metabolism, and toxicity. Crit Rev Env Sci Tec 50(11):1116–1193. https://doi.org/10.1080/10643389.2019.1647028 CAS  Article  Google Scholar Choubisa SL (2015) Industrial fluorosis in domestic goats (Capra hircus), Rajasthan. India Fluoride 48(2):105–112 CAS  Google Scholar Szczuko M, Splinter J, Zapalowska-Chwyc M, Zietek […]

  • Effect of Fluoride on Cytotoxicity Involved in Mitochondrial Dysfunction: A Review of Mechanism.

      Fluoride is commonly found in the soil and water environment and may act as chronic poison. A large amount of fluoride deposition causes serious harm to the ecological environment and human health. Mitochondrial dysfunction is a shared feature of fluorosis, and numerous studies reported this phenomenon in different model systems. More and more evidence […]

  • NTP & TSCA Trial 2020: Human Studies Cited by Each

    The following are the majority of studies introduced into the TSCA trial or cited by the National Toxicology Program (NTP). Eventually, all the human studies introduced into the trial or into NTP’s documents on fluoride’s neurotoxicity will be listed here. Codes Date: Published in English NTP-1 : Human Studies that were used in the National […]

  • Protected: Draft. TABLE NTP 2019. ANIMAL STUDIES

    There is no excerpt because this is a protected post.

  • DNA methylation and fluoride exposure in school-age children: Epigenome-wide screening and population-based validation.

    4. Discussion Water-borne endemic fluorosis has been widely prevalent in China, especially in the central, western and northern parts of China. In order to explore the possible epigenetic changes caused by fluoride exposure, we conducted a screening and validation study in step by step. We undertook, for the first time, microarray analyses of DNA methylation […]

  • Environmental Fluoride 1977 by Rose & Marier

    The Associate Committee on Scientific Criteria for Environmental Quality was established by the National Research Council of Canada in response to a mandate provided by the Federal Government to develop scientific guidelines for defining the quality of the environment. The concern of the NRC Associate Committee is strictly with scientific criteria. Pollution standards and objectives […]

  • Critical Windows of Fluoride Neurotoxicity in Canadian Children.

    Discussion We used data from a prospective pregnancy and birth cohort to compare the associations between fluoride exposures during different developmental windows and preschool aged children’s intellectual abilities. The GEE method advances our understanding of early-life fluoride neurotoxicity by formally comparing strength of associations across windows of exposure. The strongest association between fluoride and child […]

  • India’s infertility war: Exposure to chemicals lowers sperm count, egg quality

    Until about a decade ago, weekdays at the Agatsya Sperm Bank in Rajkot saw men, aged between 20 to 30 years, queue up outside the facility. A quick screening, and the young, athletic, qualified, English-speaking men among them would be picked out. For, it would be certain that they would have sufficient volumes of “healthy […]