NTP 2021: The 2nd NASEM Peer Review
Released February 9, 2021:
The second peer-review by the National Academies of Sciences, Engineering, and Medicine (NAS) of NTP’s Revised Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Letter Report.
Concurrently with the release of their peer-review, NAS issued a News Release. Some excerpts:
… The committee that wrote the National Academies report was tasked with reviewing the second draft of the monograph and focused on evaluating whether evidence as presented in the revised monograph supports NTP’s conclusions. The committee reviewed the first draft of the monograph in 2020. The committee did not conduct its own independent evaluation of the evidence in either review, nor did it conduct a data audit.
The new National Academies report recognizes the efforts made to revise the monograph and address some concerns previously raised. However, the second draft of the monograph still falls short of providing clear and convincing documentation of the evidence to support its conclusions. The monograph needs to emphasize that much of the evidence presented comes from studies that involve relatively high fluoride concentrations, and to make clear that the monograph cannot be used to draw conclusions about low fluoride exposure concentrations (less than 1.5 mg/mL), including those in fluoridated drinking water systems.
The monograph has great importance in the discussion about effects of fluoride on neurodevelopmental and cognitive health effects. It is critical for the monograph to be able to withstand scientific scrutiny by those who have vastly different opinions on the risks and benefits associated with fluoride exposure given that the issue has become highly contentious. Therefore, the committee strongly recommends that NTP improve the revised monograph by implementing its suggestions to improve clarity and transparency…
|Documents and News Reports leading up to, and including, 2021
|Sept 6, 2019||NTP||The NTP’s first Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|March 5, 2020||NAS||The NAS’ first peer review of the Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|Sept 16, 2020||NTP||The NTP’s revised (second) Draft Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|NEURATH: DOSE RESPONSE DOCUMENTS:
• FAN dose-response assessment of Nov. 30, 2020
• Appendix which provides the computer code used to generate the meta-analyses and meta-regressions
• Data file in Excel format.xlsx”
• Updated ISEE 2020 Conference poster
• Supporting details for dose-response analysis summaries shown in ISEE 2020 Conference poster
• A zip file for:
Dose response analysis
Meta-analysis data high quality NTP studies
|Feb 9, 2021||NAS||The NAS’ second peer-review of the revised (second) Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Letter Report.
|Feb 9 2021||NAS||National Academies Complete Review of National Toxicology Program’s Second Draft Monograph on Fluoride Exposure and Neurodevelopmental and Cognitive Effects. Press Release from the National Academies.
|Feb 11, 2021||ADA||National Academies ’strongly recommends’ third revision to fluoride monograph. By Jennifer Garvin. ADA News (American Dental Association).
|Feb 11, 2021||AFS||National Academies rejects the NTP draft report about fluoride. Press Release. American Fluoridation Society.
|Feb 16, 2021||FAN||According to Fluoride Action Network, the NAS strengthens findings on fluoride’s neurotoxicity. Press Release, Fluoride Action Network.