Abstract
Background and Aim: Human and animal studies linking fluoride with diminished intelligence have been published. Although adverse effects of high intake of fluoride on intelligence and mental acuity continue to be reported, they are still controversial. The aim of this research was to investigate the relationship between fluoride in drinking water and children’s intelligence.
Materials and Methods: In this cross sectional study, 41 children were selected from the high fluoride area with 2.5mg/l (ppm) fluoride in the drinking water and 85 children were selected from low fluoride area with 0.4mg/l (ppm) fluoride in the drinking water. The intelligence quotient (IQ) of each child was measured by the Raven’s test. The history of illnesses affecting the nervous system, head trauma, birth weight (>2.5kg or >2.5kg), residental history, age and sex of children were investigated by questionnaires completed by the children’s parents. Data were analyzed by Chi-Square test with p<0.05 as the limit of significance.
Results: In the high fluoride area the mean IQ of children (87.9±11) was significantly lower than in the low fluoride area (98.9±12.9) (P=0.025).
Conclusion: Based on the findings of this study, exposure of children to high levels of fluoride may carry the risk of impaired development of intelligence.
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Effect of coal-burning endemic fluorosis on children's physical development and intellectual level
Objective To investigate the effect of coal-burning endemic fluorosis on children's physical development and intellectual level so as to provide data support for the protection of children's healthy growth in fluorosis areas. Methods Ninety children with coal-burning endemic fluorosis were selected for the study, which were divided into heavy fluorosis area group, middle
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Effect of fluoride in drinking water on children's intelligence in high and low fluoride areas of Delhi
Introduction: Fluoride is one of the indispensable elements for the living being. However, the intake of F above the threshold level can affect the central nervous system even before causing dental or skeletal fluorosis. Aim: The aim was to assess the effect of fluoride in drinking water on the intelligence quotient
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Investigation and analysis of the development of intelligence levels and growth of children in areas suffering fluorine and arsenic toxicity from pollution from burning coal
Aim: To study the impacts on the development of intelligence and growth of children suffering fluorine and arsenic toxicity from pollution from burning coal. Method: Areas suffering from significant morbidity and minor morbidity were selected for investigation from areas of southern Shaanxi Province suffering fluorine and arsenic toxicity from pollution from
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Do methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 polymorphisms modify changes in intelligence of school-age children in areas of endemic fluorosis?
Background: Excessive exposure to fluoride can reduce intelligence. Methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 (MTHFD1) polymorphisms have important roles in neurodevelopment. However, the association of MTHFD1 polymorphisms with children's intelligence changes in endemic fluorosis areas has been rarely explored. Methods: A cross-sectional study was conducted in four randomly selected primary schools in
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A preliminary investigation of the IQs of 7–13 year old children from an area with coal burning-related fluoride poisoning.
The Chinese Binet IQ Test was used to investigate the IQs of 7–13 year- old children suffering from dental fluorosis, living and attending school in an area with coal burning-related fluoride poisoning. The average IQ of these children was found to be markedly lower than in the control area, and
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Fluoride & IQ: 76 Studies
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Fluoride Affects Learning & Memory in Animals
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Fluoride: Developmental Neurotoxicity.
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Fluoride's Direct Effects on Brain: Animal Studies
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Fluoride's Effect on Fetal Brain
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