Abstract
The present research report has looked into the correlation between male infertility and the fluoride level in water, the occurrence of dental and skeletal fluorosis, [the volume and quality of] semen and the amount of fluoride contained therein. Results have shown that fluoride might be a leading cause of male infertility in regions with endemic fluorosis.
-
-
Fluoride interferes with sperm fertilizing ability via downregulated SPAM1, ACR and PRSS21 expression in rat epididymis.
Fluoride is a widespread environmental pollutant which can induce low sperm quality and fertilizing ability, however, the underlying mechanism is still remaining unclear. Hence, we aimed to investigate the influence of fluoride on sperm fertilizing ability via some key proteins in epididymis. For this, forty adult rats were assigned randomly
-
The influence of fluorides on mouse sperm capacitation
Increasing infertility, due to pathological changes on sperm, has become a serious issue. Eco-toxicological effect of rising concentration of fluorides can be enhanced in the presence of aluminium ions by forming fluorometallic complexes, analogues of phosphate groups that interfere with the activity of G-proteins and P-type ATPases, which are part
-
Fertility effects of sodium fluoride in male mice
Sexually mature male Swiss mice were exposed at 60 days of age to 100, 200 and 300 ppm sodium fluoride (NaF) in their drinking water for 4 weeks or 10 weeks. The effect of NaF exposure on fertility was assessed by breeding these males with untreated female mice after the
-
Reversal of fluoride-induced alteration in cauda epididymal spermatozoa and fertility impairment in male mice
The effects of sodium fluoride (NaF) ingestion (10 mg NaF/kg body weight) and the possible therapeutic effects of ascorbic acid (AA, 15 mg/animal/day) and/or calcium phosphate (Ca, 25 mg/animal/day) on the reproductive functions and fertility of male mice were investigated. NaF-ingestion brought about a significant decline in sperm acrosomal acrosin
-
Effect of fluoride intake on repduction in mice
Female mice were fed a low fluoride diet (0.1 to 0.3 ppm fluoride) plus drinking water containing 0, 50, 100 or 200 ppm fluoride as sodium fluoride. Toxic effects of fluoride were evidenced by retarded growth and impaired reproduction in mice with intakes of 100 and 200 ppm fluoride, and
Related Studies :
-