Abstract
Effects of fluoride (F) on electrocardiogram (ECG) values were determined in ten healthy adult male New Zealand white rabbits. After the initial ECG values were measured, the rabbits were administered 20 mg NaF/kg body weight by oral intubation for two months, and the new ECG values were determined. There was a significant (p<0.001) decrease in the R-R interval (duration between the peaks of two consecutive R waves of ECG) and P-R interval (duration from the starting of P wave to the starting of QRS complex in ECG), while significant (p<0.001) increases in the mean heart rate and corrected QT intervals were observed compared to the initial baseline values. The results indicate that F adversely affects the ECG in male rabbits.
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Electrocardiographic studies of the inhabitants in high fluoride districts
1) In the Aso-volcano district, a higher incidence of myocardial damage based on electrocardiographic studies was found in inhabitants of high fluoride communities than in "nonfluoride" villages. 2) In subjects with mottled teeth, greater myocardial damage was encountered electrocardiographically than in persons without mottling in the Asovolcano district. 3) The authors conclude
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Alterations in electrocardiographic parameters after subacute exposure of fluoride and ameliorative action of aluminium sulphate in goats
Fluorosis or crippling disease is one of the existing environmental challenges for animal and human beings in most parts of the globe. In the present study, sodium fluoride alone and with aluminium sulphate (ameliorative agent) was administered orally daily for 30 days in healthy goats of group 1 and 2,
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Impact of chronic fluorosis on left ventricular diastolic and global functions.
Sixty three patients with endemic fluorosis (36 males/27 females; mean age 33.9+/-8.6years) and 45 age, sex and body mass index (BMI) matched healthy controls (30 males/15 females; mean age 32.7+/-8.8years) were included in this study. Basic echocardiographic measurements, left ventricular diastolic parameters and left ventricular myocardial performance index (MPI) were
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Effects of chronic fluorosis on electrocardiogram in dogs
The aim of this study was to determine the effects of chronic fluorosis on the electrocardiogram (ECG) in dogs. A total of sixteen mixed breed dogs (8 fluorotic and 8 healthy), 2 to 3 years old and weighing 18–30 kg, were used in this study. The eight dogs with chronic
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Electrocardiographic evaluation in patients with endemic fluorosis without clinically evident heart disease
Objective: This study was carried out to analyse the electrocardiogram (ECG) in patients with endemic fluorosis. Methods: Fifty six patients with endemic fluorosis and 44 age, sex and body mass index (BMI) matched healthy controls with normal fluoride intake underwent standart 12-lead ECG, urine fluoride level and serum sodium, potassium,
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Fluoride & Electrocardiogram Abnormalities
An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems
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Fluoride, Blood Pressure and Hypertension
Individuals with blood pressure readings that exceed 140/90 are considered hypertensive. Hypertension can increase the risk of stroke, heart attack, heart failure, aortic aneurysms, and peripheral arterial disease. An association between increased fluoride in ground water and increased prevalence of hypertension has been observed, especially among adult males (Amini et
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Fluoride & Myocardial Damage
Structural damage to the heart resulting from fluoride toxicity has been observed in numerous human and animal studies. The general features of this damage include cloudy swelling, vacuolization or vacuolar degeneration, hemorrhages, interstitial edema, fibrous necrosis, dissolution of nuclei, and thickening of the vessel walls in the heart muscle (Basha
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Fluoride & Arteriosclerosis
Healthy arteries are flexible and elastic, allowing efficient transfer of blood and nutrients from the heart to the rest of the body. Arteriosclerosis refers to a stiffening of the arteries, including loss of elasticity. This is a slow, progressive disease that may begin early in life from damage to the
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Fluoride & Arterial Calcification
The major change involved with cardiovascular disease is development of atherosclerosis in critical arteries, which is partially characterized by vascular calcification. The level of coronary artery calcification is thought to be the most important indicator of future cardiovascular events. Increased arterial calcifications have frequently been reported in those with skeletal fluorosis
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