Abstract

Objective To probe into X-ray, CT and MRI manifestations of bone turnover in skeletal fluorosis and diagnostic values of different examination technologies. Methods Comparisons and analyses were made on the imaging manifestations of bone turnover in 28 reported cases with skeletal fluorosis. Results All 28 cases had dental fluorosis of different degrees. The chief symptoms included arthralgia and aching muscle pains in four limbs; 13 cases had joint motion limitation and dysfunction, 28 cases had spinal pain and 26 cases (92.85%) had pain in the lumbar region and legs. As to the imaging manifestations, 17 cases mainly had hyperostosis and 11 cases mainly had osteopenia; 5 had fuzzy bone trabecula, 9 loosening of cortical bone and 19 sclerosis of cancellous bone; 7 cases were complicated by biconcave deformity of vertebral body and 6 cases by pelvic deformity; 4 cases manifested the formation of false fracture line, and 7 cases manifested disorder of bone growth and development. Conclusions: MRI may distinctly display early changes of bone turnover in patients with skeletal fluorosis with high diagnostic sensitivity.

• Related Studies :

  • Radiological analysis of fluorotic elbow arthritis

    This article has reported the radiological signs in 109 cases of fluorotic elbow arthritis: sclerosis, irregularity and discontinuity of the articular surfaces; coarsened bone striation below the articular surface, trabecular coarsening and rarefaction, sparseness of trabeculae or density changes along with areas of cystic radiolucency. The author first suggested osteophyte

  • Occupational skeletal fluorosis

    Conclusion Four cases of skeletal fluorosis are described in individuals who had been working in an aluminum plant for periods up to 12 yens. Two patients exhibited radiological changes indicative of the first stage of the disease and two of the second stage. All patients exhibited backache, pains in arms and

  • Enduring fluoride health hazard for the Vesuvius area population: the case of AD 79 Herculaneum

    BACKGROUND:  The study of ancient skeletal pathologies can be adopted as a key tool in assessing and tracing several diseases from past to present times. Skeletal fluorosis, a chronic metabolic bone and joint disease causing excessive ossification and joint ankylosis, has been only rarely considered in differential diagnoses of palaeopathological

  • Dorsal spondylolisthesis secondary to chronic fluoride intoxication: one case report

    Fluorosis is a disease caused by an excess of fluoride in the water, it is endemic in many parts of India,Afghanistan; Irak, Iran and North Africa. Fluoride is retained in the bones and induces hardening of all the bones, including the spine, hypertrophy of the joints and bones is seen,

  • Recovery from skeletal fluorosis (an enigmatic, American case)

    A 52-year-old man presented with severe neck immobility and radiographic osteosclerosis. Elevated fluoride levels in serum, urine, and iliac crest bone revealed skeletal fluorosis. Nearly a decade of detailed follow-up documented considerable correction of the disorder after removal of the putative source of fluoride (toothpaste). INTRODUCTION: Skeletal fluorosis, a crippling bone

• Related FAN Content :

  • Fluoride & Osteoarthritis

    While the osteoarthritic effects that occurred from fluoride exposure were once considered to be limited to those with skeletal fluorosis, recent research shows that fluoride can cause osteoarthritis in the absence of traditionally defined fluorosis. Conventional methods used for detecting skeletal fluorosis, therefore, will fail to detect the full range of people suffering from fluoride-induced osteoarthritis.

  • Skeletal Fluorosis: The Misdiagnosis Problem

    It is a virtual certainty that there are individuals in the general population unknowingly suffering from some form of skeletal fluorosis as a result of a doctor's failure to consider fluoride as a cause of their symptoms. Proof that this is the case can be found in the following case reports of skeletal fluorosis written by doctors in the U.S. and other western countries. As can be seen, a consistent feature of these reports is that fluorosis patients--even those with crippling skeletal fluorosis--are misdiagnosed for years by multiple teams of doctors who routinely fail to consider fluoride as a possible cause of their disease.

  • "Pre-Skeletal" Fluorosis

    As demonstrated by the studies below, skeletal fluorosis may produce adverse symptoms, including arthritic pains, clinical osteoarthritis, gastrointestinal disturbances, and bone fragility, before the classic bone change of fluorosis (i.e., osteosclerosis in the spine and pelvis) is detectable by x-ray. Relying on x-rays, therefore, to diagnosis skeletal fluorosis will invariably fail to protect those individuals who are suffering from the pre-skeletal phase of the disease. Moreover, some individuals with clinical skeletal fluorosis will not develop an increase in bone density, let alone osteosclerosis, of the spine. Thus, relying on unusual increases in spinal bone density will under-detect the rate of skeletal fluoride poisoning in a population.

  • Fluoride & Spinal Stenosis

    Spinal stenosis is a narrowing of the spaces in the spine that results in pressure being placed on the spinal cord and/or nerve roots. Although stenosis can develop without symptoms, it may produce numbness, tingling, pain and difficulty in walking, as well as a heavy/tired feeling in the legs. It is estimated that 250,000 to 500,000 Americans currently have symptoms of spinal stenosis. Skeletal fluorosis is one cause of stenosis.

  • Fluoride & Arthritis

    The doses that American adults now routinely ingest overlap the doses that may cause chronic joint pain.