Abstract

[Objective] To investigate the effect of iodine and selenium on learning memory behavior impairment induced by fluorosis and blood biochemical criterion change of rats. To study the antagonism of iodine and selenium on fluorosis. [Methods] After the rats with fluorosis drinking water with different concentrations of iodine ( I) and selenium ( Se) for a long time, their learning memory abilities were measured by way of Y- maze, and the blood biochemical criterions were determined at the same time. [Results] The learning memory abilities of rats in high F group, high I/high F group, and low I/high F group were significantly lower than control group, while the learning memory abilities of rats given proper concentration I and Se increased significantly. The blood biochemical criterions of high F group, high I/high F group, and low I/high F group presented marked differences from that of groups given proper concentration I and Se. [Conclusion] Proper concentration I and Se have obvious antagonism against rat fluorosis. The antagonism may be related with the changes of blood biochemical criterion.

• Related Studies :

  • The relationship of a low-iodine and high-fluoride environment to subclinical cretinism in Xinjiang.

    Cretinism in iodine-deficiency areas is well known, yet the milder forms of somatic and psychomotor maldevelopment and thyroid dysfunction caused by iodine deficiency may be more difficult to detect. DeQuervain, in 1936, called this milder form "semi-cretinism," while in 1980 Laggasse used the term "cretinoidism." It was formally named "subclinical

  • [Effects of high fluoride and low Iodine on learning-memory and TchE of brain in offspring rats].

    Objective To study the effect of high level fluoride and low level iodine on learning-memory in offspring rats and possible mechanism. Methods Thirty-two Wistar rats were randomly divided into four groups each of eight (female:male=(3:1).) The rats were treated with high fluoride (100 and 150 mg NaF/L), low iodine (0.0855 mg/kg),

  • Effects of high iodine and high fluorine on children’s intelligence and thyroid function.

    Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function. Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and

  • Research on the effects of fluoride on child intellectual development under different environments

    Goal:  To study the effects of the fluoride and iodine content of drinking water on child intellectual development and the interaction between the two factors and also the relationship of educational factors to such development. Methods: The subjects of the investigation were 8- to 14-year-old children randomly selected from endemic areas as well

  • The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.

    Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to

• Related FAN Content :

  • Fluoride Affects Learning & Memory in Animals

    An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out

  • Fluoride's Effect on Fetal Brain

    The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts

  • Fluoride & Rickets

    One of fluoride's most well-defined effects on bone tissue is it's ability to increase the osteoid (unmineralized bone) content of bone. When bones have too much osteoid, they become soft and prone to fracture -- a condition known as osteomalacia. When osteomalacia develops during childhood, it is called "rickets." The potential for fluoride

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching

  • Fluorine in the Aetiology of Endemic Goitre

    The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.