Abstract
Changes in skin electric potential following immune challenge provide a sensitive measure of the intensity of the allergic challenge. In guinea-pigs sensitised to Sodium Fluoride, Fluoridation Mains Tap Water, or Ovalbumen with Sodium Fluoride, and then challenged with one part in one million Sodium Fluoride, significant allergic responses were produced. Ovalbumen alone caused an allergic response only after a second challenge. Purified water did not result in any immune response. It is concluded that Fluoridated Mains Tap Water is capable of causing an allergic response similar to that produced by Sodium Fluoride alone, and that Ovalbumen potentiates the immune response to Sodium Fluoride.
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Contact dermatitis and stomatitis due to amine fluoride
Case Report For prevention of dental caries, a 17-year-old boy had intermittently used a gel containing different fluoride compounds over a period of 2 years. In the last 2 months, 1 to 2 days after application, he had developed itchy perioral erythematous papules and plaques, with vesicles of the oral mucosa.
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Enhancement of inflammation by fluorides
Application of ammonium fluoride under an occlusive patch to the abdomen of a rabbit converts a simple scratch into a double row of sterile pustules. Sodium fluoride produces a similar response, but ammonium chloride does not produce pustules. . . . It appears that tissue damage and the presence of fluorides
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Allergy in horses from artificially fluoridated water
As described recently in Fluoride, horses on artificially fluoridated water (AFW) developed chronic fluoride poisoning. This report describes an allergic manifestation as an addition to the classical signs of fluorosis, viz., urticaria. The skin lesions disappeared promptly when an affected horse was removed from AFW and returned promptly when the
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Recurrent benign aphthous stomatitis and fluoride allergy
Many years ago I consulted 2 patients suffering from recurrent aphthous ulceration to establish whether they had a toothpaste allergy. I thus proceeded to do many p-tests on the skin but without any positive results. However, replacement of the toothpaste with a simple soap quickly cured the ulcerations. A third
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Fluoroderma
Papulonodular eruptions from certain bromide and iodide preparations are widely recognized entities, but skin lesions following fluoride ingestion are rare. Modern prophylaxis for postirradiation dental caries includes the use of fluoride gel preparations applied to the teeth. In two patients receiving such therapy a papulonodular eruption developed, similar to the
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Allergy and Hypersensitivity to Fluoride
there are reasonable grounds for concluding that there are individuals in whom allergy or hypersensitivity to fluoride has been demonstrated.
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel
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Is the Ingestion of Fluoride an Immunosuppressive Practice?
This paper records several observations which suggest that habitual ingestion of small doses of fluoride, even as small as the 1 mg/L contained in fluoridated water, may decrease the function of the immune system.
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Nutrient Deficiencies Enhance Fluoride Toxicity
It has been known since the 1930s that poor nutrition enhances the toxicity of fluoride. As discussed below, nutrient deficiencies have been specifically linked to increased susceptibility to fluoride-induced tooth damage (dental fluorosis), bone damage (osteomalacia), neurotoxicity (reduced intelligence), and mutagenicity. The nutrients of primary importance appear to be calcium,
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Skeletal Fluorosis & Individual Variability
One of the common fallacies in the research on skeletal fluorosis is the notion that there is a uniform level of fluoride that is safe for everyone in the population. These "safety thresholds" have been expressed in terms of (a) bone fluoride content, (b) daily dose, (c) water fluoride level, (d) urinary fluoride level, and (e) blood fluoride level. The central fallacy with each of these alleged safety thresholds, however, is that they ignore the wide range of individual susceptibility in how people respond to toxic substances, including fluoride.
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