Fluoride levels of 600 samples of iliac crest bone in ash weight were correlated with age. They showed a near linearship with age. The yearly rate of accumulation of fluoride in bone was found to be 25.589 ug/g bone ash weight. This accumulation rate could be met by the ingestion of 0.867 mg/day of fluoride. The derivation of this figure is indicated and considered in relation to known ranges of dietary and other levels of fluoride ingestion.
Fluoride retention in infants living in fluoridated and non-fluoridated areas: effects of weaning.
Limited knowledge is available on total fluoride exposure, excretion and retention in infants, despite the first year of human life being the critical period for dental development and risk of dental fluorosis. This study investigated total daily fluoride intake (TDFI), excretion (TDFE) and retention (TDFR) in infants living in fluoridated
Ionic serum fluoride concentrations and age in a low-fluoride community
Some previous studies indicate extra fluoride retention in human bones caused by severe renal insufficiency. Plasma and serum fluoride concentrations may also be elevated in a fluoridated community. The results from low-fluoride areas are less consistent. The first aim of the present study was thus to test the relation between
Value of the bone biopsy in the diagnosis of industrial fluorosis
Iliac crest biopsies taken from 43 men with industrial fluorosis were compared with control bone samples. The bone fluoride content was determined, histological examinations were made on stained sections and microradiographs, and morphometric analysis performed on the microradiographs alone. In the subjects with fluorosis, the bone fluoride content (5617 +/- 2143
Bone fluoride concentrations associated with fluoridated drinking water
Recently published bone fluoride values from Iowa are very high compared to earlier reports, suggesting an increase in fluoride intake. Reanalysis of the Iowa specimens shows levels one-fourth those reported by the Iowa laboratory indicating an error in the original report. Seventeen bone specimens, collected from long-term residents of Rochester,
Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6–12 Years of Age in Mexico
Background: Some evidence suggests that fluoride may be neurotoxic to children. Few of the epidemiologic studies have been longitudinal, had individual measures of fluoride exposure, addressed the impact of prenatal exposures or involved more than 100 participants. OBJECTIVE: Our aim was to estimate the association of prenatal exposure to fluoride with
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