Abstract

This paper reports the effect of chronic high fluoride exposure on children’s intelligence quotient (IQ). In this cross sectional study, two urban communities with similar socio-economic and cultural status but with different levels of fluoride in drinking water, in Kerman province of Iran were studied: Koohbanan City (fluoride 2.38 mg/L), Baft City (fluoride 0.41 mg/L). Study samples consisted of 119 children 6 to 9 years old: 50 children from Koohbanan and 60 children from Baft. Raven’s progressive matrices used to determine the effect of fluoride exposures on children’s IQ. The statistical analysis was carried out using the t-test, the chi-square test and the Mann-Whiteney test. In the low fluoride area (control group), the mean IQ score of children was 97.80±15.95 that decreased to 91.37±15.63 for the high fluoride group (Koohbanan’s children), it was significantly different from the control group (P<0.05). Although fluoride is widely promoted for prevention of dental caries, its overconsumption may lead to dental fluorosis and other adverse effects. Based on the findings, the chronic exposure to high levels of fluoride can be one of the factors that influence intellectual development. Therefore, it is necessary to think about some solutions for preventing the bad effects of excessive intake of fluoride ion to the body, especially in cities like Koohbanan.

T

Print PDF

• Related Studies :

  • Do methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 polymorphisms modify changes in intelligence of school-age children in areas of endemic fluorosis?

    Background: Excessive exposure to fluoride can reduce intelligence. Methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 (MTHFD1) polymorphisms have important roles in neurodevelopment. However, the association of MTHFD1 polymorphisms with children's intelligence changes in endemic fluorosis areas has been rarely explored. Methods: A cross-sectional study was conducted in four randomly selected primary schools in

  • Community water fluoridation and intelligence: prospective study in New Zealand

    OBJECTIVES:  This study aimed to clarify the relationship between community water fluoridation (CWF) and IQ. METHODS: We conducted a prospective study of a general population sample of those born in Dunedin, New Zealand, between April 1, 1972, and March 30, 1973 (95.4% retention of cohort after 38 years of prospective follow-up).

  • Comparative assessment of intelligence quotient among children living in high and low fluoride areas of Kutch, India: a pilot study

    Background: Long-term ingestion of large amounts of fluoride can lead to potentially severe skeletal problems and neurological consequences. The study was conducted to assess and compare intelligence quotient of children living in high and low fluoride areas in Kutch, Gujarat, India. Methods: A cross-sectional descriptive survey was conducted among 100 school

  • Investigation and analysis of the development of intelligence levels and growth of children in areas suffering fluorine and arsenic toxicity from pollution from burning coal

    Aim: To study the impacts on the development of intelligence and growth of children suffering fluorine and arsenic toxicity from pollution from burning coal. Method: Areas suffering from significant morbidity and minor morbidity were selected for investigation from areas of southern Shaanxi Province suffering fluorine and arsenic toxicity from pollution from

  • Low-moderate fluoride exposure and intelligence among Chinese school-aged children: Role of circulating mtDNA content.

    Highlights First epidemiologic study links mtDNA content with fluoride-caused lower IQ scores. MtDNA content was positively correlated to odds of having excellent intelligence. MtDNA content mediated relations of fluoride to reduced odds of excellent intelligence in girls. Mitochondrial DNA (mtDNA) content alterations are potential mediators of neuronal disorders. However, what

• Related FAN Content :

  • Fluoride & IQ: 76 Studies

    Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies

  • Fluoride Affects Learning & Memory in Animals

    An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching

  • Fluoride's Effect on Fetal Brain

    The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts

  • Fluoride's Direct Effects on Brain: Animal Studies

    The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.