Recently published bone fluoride values from Iowa are very high compared to earlier reports, suggesting an increase in fluoride intake. Reanalysis of the Iowa specimens shows levels one-fourth those reported by the Iowa laboratory indicating an error in the original report. Seventeen bone specimens, collected from long-term residents of Rochester, New York, drinking 1 ppm F- water, had a mean value of 2085 +/- 270 ppm F- on an ashed-weight basis. This value is not significantly different from that predicted by the data of Zipkin et al. in 1958. These data, therefore, do not support the contention that there has been an increase in fluoride intake.
Fluoride in synovial fluid, bone marrow, and cartilage in patients with osteoarthritis.
The aim of this study was to comp are the concentrations of fluoride (F) in cartilage, bone marrow, and synovial fluid taken from patients with osteoarthritis (OA). We also determined the correlation between OA risk factors, including age, sex, obesity, and hypertension, and F concentrations in the studied materials. The
A mathematical model for fluoride uptake by the skeleton
A mathematical model was developed that predicts fluoride accumulation and clearance from the skeleton based upon fluoride bioavailability, bone remodeling rate, and the fluoride binding characteristics of bone. It was assumed that fluoride binds to bone in a nonlinear fashion such that a smaller percentage of fluoride is bound to
Fluoride and strontium accumulation in bone does not correlate with osteoid tissue in dialysis patients
BACKGROUND: Osteomalacia is now a rare disease in dialysis patients in developed countries since the withdrawal of aluminium overload. The involvement of fluoride and strontium in the pathogenesis of the disease has been suggested. The aim of this study was to investigate a possible association between osteomalacia in dialysis patients
When less is more: a comparison of models to predict fluoride accumulation in free-ranging kangaroos.
Highlights Exposure models can predict toxic effects of fluoride consumption in wildlife. Exposure models that vary in intensity of field data collection warrant comparison. Simple spatial metrics can predict fluoride accumulation in a free-ranging mammal. Complex exposure models may not perform better than simple spatial metrics. Vegetation contaminated by industrial fluoride
Non-Endemic Skeletal Fluorosis: Causes And Associated Secondary Hyperparathyroidism (Case Report and Literature Review).
Highlights Fluorocarbon “huffing” is an under-appreciated cause of skeletal fluorosis (SF) We present a SF case with hyperparathyroidism, osteosclerosis, and osteomalacia SF may go undetected due to variation in symptoms, radiology, and biochemistry Dietary calcium, prior bone health, and skeletal F exposure influence SF features SF is common in
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