Abstract
The purpose was to discover whether fluoride (F) accumulates in the aged human pineal gland. The aims were to determine (a) F-concentrations of the pineal gland (wet), corresponding muscle (wet) and bone (ash); (b) calcium-concentration of the pineal. Pineal, muscle and bone were dissected from 11 aged cadavers and assayed for F using the HMDS-facilitated diffusion, F-ion-specific electrode method. Pineal calcium was determined using atomic absorption spectroscopy. Pineal and muscle contained 297+/-257 and 0.5+/-0.4 mg F/kg wet weight, respectively; bone contained 2,037+/-1,095 mg F/kg ash weight. The pineal contained 16,000+/-11,070 mg Ca/kg wet weight. There was a positive correlation between pineal F and pineal Ca (r = 0.73, p<0.02) but no correlation between pineal F and bone F. By old age, the pineal gland has readily accumulated F and its F/Ca ratio is higher than bone.
-
-
Fluoride in the brain and pineal gland of two duck species, Aythya Fuligula and Melanitta Fusca, wintering in northwestern Poland
Fluoride (F–) deposits formed, e.g., in bones, have hitherto mainly been analyzed in highly mineralized tissues obtained from mammals and only rarely from birds. Under certain conditions, F– may also accumulate significantly in the brain and pineal gland and interfere with the secretion of melatonin by that gland. The mammalian and avian pineal gland is
-
The Effect of Fluoride on the Physiology of the Pineal Gland
The purpose was to discover whether fluoride (F) accumulates in the pineal gland and thereby affects pineal physiology during early development. The [F] of 11 aged human pineals and corresponding muscle were determined using the F-electrode following HMDS/acid diffusion. The mean [F] of pineal gland was significantly higher (p <
-
Evidence of selected nephrotoxic elements in Sri Lankan human autopsy bone samples of patients with CKDu and controls.
Background This article describes the analysis and interpretation of data relating to the presence of cadmium, lead, mercury and fluoride in human bone samples obtained from cadavers of patients dying of Chronic Kidney Disease of uncertain aetiology (CKDu) in a case-control study, which the authors believe to be the first in
-
Salivary fluoride levels following application of fluoride varnish or fluoride rinse
OBJECTIVES: This study examined the concentration of fluoride in whole saliva over time following the application of a fluoride varnish or a single rinse with a fluoride solution. METHODS: A two-period, two-treatment randomized cross-over experimental trial with a 2-week washout period was used with 16 adult subjects. In the first period,
-
No evidence of transfer of fluoride from plasma to breast milk.
Artificially fluoridated drinking water is supplied throughout the world as a mass-prophylactic against dental caries. No data are available, however, on the transfer of fluoride from maternal plasma to breast milk. We have therefore compared the fluoride concentration in the plasma and breast milk of nursing mothers after an oral
Related Studies :
-
-
-
Luke (2001): Fluoride Deposition in the Aged Human Pineal Gland
This study has added new knowledge on the fate and distribution of fluoride in the body. It has shown for the first time that fluoride readily accumulates in the human pineal gland although there was considerable inter-individual variation
-
Luke (1997): The Effect of Fluoride on the Physiology of the Pineal Gland (Excerpts)
"The results suggest that fluoride is associated with low circulating levels of melatonin and this leads to an accelerated sexual maturation in female gerbils. The results strengthen the hypothesis that the pineal has a role in pubertal development."
Related FAN Content :
-