Abstract
In pursuit of former observations on hydrofluorosis the authors conducted an investigation concerning the incidence of goiter and the function of the thyroid gland in subjects with hydrofluorosis from Aquaviva Platani, a large endemic center of Sicily. To evaluate thyroid function, radio-iodine uptake and the conversion index (PBI) with 131I were adopted. The incidence of goiter was not higher in endemic centers of hydrofluorosis than in nonfluorotic areas. Endemic goiter in hydrofluorotic areas is not attributable to the action of fluoride.
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Significance of fluorides in potable water in the development of endemic goiter.
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[The content of fluorine in the external environment of the Upper Altai autonomous region and its role in the etiology of endemic goiter].
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[Iodized-fluoridized salt for the prevention of goiter and caries].
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[The fluorine content in water, soil and vegetal products of the Alma-Atinsk district areas and its role in the etiology of dental caries and endemic goiter].
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Fluorine and thyroid gland function: a review of the literature
The increasing use of fluoride for prevention of dental caries poses the problem as to whether this halogen has antagonistic properties towards iodine, whereby it could hamper the success of iodine prophylaxis of endemic goitre. Review of the literature shows that some authors have found an inhibition by fluoride of
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride, Water Hardness, and Endemic Goitre
Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake
Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.
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