Abstract
As part of a 2002-2003 investigation on the effects of high fluoride drinking water on IQ scores of children, serum fluoride (F) levels in the children were subjected to further study. Among the new findings, although IQ scores of boys and girls differed in the seven IQ level categories, there were no overall gender differences (boy/girl ratio 1.220 vs. 1.214 in the high and low F villages, respectively). However, the mean IQ was significantly higher and there were fewer children with an IQ less than 80 in the two quartiles with a serum fluoride level of less than 0.05 mg F/ L. Analysis of the overall relationship between IQ scores and serum F levels indicates there may be no serum F level below which adverse effects on IQ might not be present.
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Studies of relationships between the polymorphism of COMT gene and plasma proteomic profiling and children’s intelligence in high fluoride areas
Part I – Effect of high F drinking water on children’s IQ Objective: To investigate the relationships among the children’s serum F, urine F, thyroid hormone levels and children’s IQ in the high fluoride areas. Methods: We collected the samples of the drinking water, urine and blood and measured the F concentrations,
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Developmental neurotoxicity of fluoride: a quantitative risk analysis toward establishing a safe daily dose of fluoride for children
Background: A recent 2015 study from New Zealand indicated water fluoridation did not have an effect on children’s IQs. A 2012 meta-analysis showed that children with higher fluoride exposure have lower IQs than similar children with lower exposures. Levels of the fluoride ion (F) in blood and urine in children
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A correlation between serum vitamin, acetylcholinesterase activity and IQ in children with excessive endemic fluoride exposure in Rajasthan, India
Fluoride is widely distributed in nature and a direct source of adverse health effects in human populations. Fluoride poisoning attributed by long-term exposure to high levels of fluoride [is] called fluorosis. The present study was carried out among 9-14 years old school children of Dausa district, Rajasthan India. The subjects
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Cognitive impairment and risk factors in elderly people living in fluorosis areas in China
Residents living in fluorosis areas generally experienced long-term exposure to excessive fluoride in drinking water. The adverse effects of high fluoride levels on the nervous system have been studied; however, the effect of fluoride exposure on cognitive functions of elderly people in fluorosis areas is rarely reported. This study was
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Fluoride exposure and reported learning disability diagnosis among Canadian children: Implications for community water fluoridation.
OBJECTIVES: Recent studies have connected increased fluoride exposure with increased risk of neurodevelopmental-related outcomes, such as ADHD (attention deficit hyperactivity disorder) and lower IQ in children. Our primary objective was to examine the association between fluoride exposure and reported diagnosis of a learning disability among a population-based sample of Canadian
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Fluoride & IQ: 68 Studies
As of February 2021, a total of 76 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 68 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or
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