Abstract

The effects of fluoride aerosol inhalation on mice were studied using an inhalation chamber. Five-week-old male ICR mice were exposed to airborne fluoride (13.3 mgF/m³) 4 hr per day for 10, 20 or 30 days. Significant differences in relative lung weight were observed between the exposed groups and the control. No significant changes were found in relative kidney weight and body weight of the exposed mice. Bone fluoride retention and urinary fluoride excretion increased with exposure time.

• Related Studies :

  • Lessons learned from reviewing a hospital’s disaster response to the hydrofluoric acid leak in Gumi city in 2012.

    Abstract Background This study analyzed the characteristics of hydrogen fluoride-exposed patients (HFEPs) treated in the emergency department (ED) of a local university hospital, and reviewed the hospital’s disaster response according to space, staff, supplies, and systems (4Ss). Methods This retrospective observational chart review and descriptive study included 199 HFEPs among 2588 total ED patients

  • Epistaxis in a low level hydrogen fluoride exposed industrial staff

    OBJECTIVES: To assess the effect of exposure to hydrogen fluoride (HF) on the airway mucosa in an industrial setting. METHODS: A cross-sectional study encompassing 33 industrial workers in a flame soldering plant and 44 assembly workers unexposed to HF was performed by means of a questionnaire on symptoms and diagnosis regarding

  • Royal jelly regulates the caspase, Bax and COX-2, TNF-a protein pathways in the fluoride exposed lung damage in rats

    Highlights Royal jelly (RJ) has antiinflammatory and antioxidant activity. RJ protects lung tissue against fluoride damage. RJ up-regulates the expression of caspase-3, caspase-6, caspase-9, Bax and BDNF proteins. RJ down-regulates the expression of bcl-2, COX-2, TNF-a and GSK3 proteins. The study was carried out on 42 male rats divided into

  • Mortality and cancer morbidity after heavy occupational fluoride exposure

    A cohort of 431 male cryolite workers employed for at least six months between 1924 and 1961 was identified from personnel records at the Copenhagen cryolite factory. During this period, heavy fluoride exposure resulted in at least 74 cases of skeletal fluorosis. All workmen in the cohort were followed up

  • Increased CD3 positive cells in bronchoalveolar lavage fluid after hydrogen fluoride inhalation

    OBJECTIVES: This study examined whether experimental hydrogen fluoride exposure for 1 hour induces an inflammatory response in the lower respiratory tract that is detectable in bronchoalveolar lavage fluid. METHODS: Nineteen healthy, nonsmoking men were exposed for 1 hour to constant low (<0.6 mg/m3), intermediate (0.7-2.4 mg/m3), or high (2.5-5.2 mg/m3) concentrations

• Related FAN Content :

  • Fluoride Enhances Toxicity of Beryllium

    Occupational exposure to beryllium is well-documented to put workers' health at risk. The two principal targets of beryllium poisoning are the respiratory system and the skin. Of all beryllium compounds, beryllium fluoride complexes (including beryllium fluoride and beryllium oxyfluoride) appear to be the most toxic. As shown below, studies dating back

  • Respiratory Risks from Occupational Fluoride Exposure

    Starting in the 1930s, scientists have observed that workers exposed to airborne fluorides suffer from an elevated rate of respiratory disorders. For over 50 years, however, US government and industry scientists made repeated assurances that the allowable level of fluoride dusts and gases in industrial workplaces would not cause any