To investigate the effect of coal-burning endemic fluorosis on children’s physical development and intellectual level so as to provide data support for the protection of children’s healthy growth in fluorosis areas.
Ninety children with coal-burning endemic fluorosis were selected for the study, which were divided into heavy fluorosis area group, middle fluorosis area group and light disease area group. 30 children in each group. Another 30 children were selected from non-fluorosis areas as normal group. The index of physical development and intellectual level of each group were compared.
Dental fluorosis and urinary fluoride concentration of fluorosis area groups were higher than that of normal group (P<0.05); index of height, weight and vital capacity in normal group children’s was significantly better than that of other 3 groups (P<0.050); intelligence quotient (IQ) index in fluorosis groups was lower than that of normal group (P<0.05).
The coal-burning endemic fluorosis may have a serious impact on children’s physical growth and intellectual level, active preventive measures should be attached to protect children’s health.
Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.
Highlights Urine fluoride was inversely associated with IQ. IQ of children with high-activity MAOA genotype was lower than IQ of those with low-activity or female heterozygote genotype. DAT1 and MAOA gene polymorphism modify the effects of UF on IQ. UF, ANKK1, COMT and MAOA have a high-dimensional interaction on
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Effects of high iodine and high fluorine on children’s intelligence and thyroid function.
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Arsenic and fluoride exposure in drinking water: children’s IQ and growth in Shanyin County, Shanxi Province, China.
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