Abstract

From the survey by Kilpatrick et al. (p. 654, col. 1, Vol. 32) it was possible to classify 696 schoolgirls in 4 groups according to intake of I, which was higher in those taking school lunches than in those not doing so because iodised salt was used for cooking, and according to intake of F, in some areas 0.7 and in others <02 p.p.m. in drinking water. Enlargement of thyroid had been assessed on 3 bases, visibly enlarged, not visibly enlarged, but with lobes palpably enlarged, or enlarged at isthmus but not necessarily at lobes. There was no indication that F was goitrogenic; its addition to water was not precluded. D. Harvey.

• Related Studies :

  • [Effects of fluoride on the thyroid morphology and thyroid peroxidase and serum thyroid hormones].

    Objective To observe the effects of fluoride on thyroid morphology,thyroid peroxidase and serum thyroid hormones. Methods One - month ablactating SD rats were randomly divided into three groups:the control group, low-fluoride group, middle-fluoride group, high-fluoride group, fed with water containing different fluoride concentration by adding NaF respectively. Rats were sacrificed after

  • Prevalence and manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India: a preliminary study

    Background: Fluorosis is an endemic condition with prevalence in 19 states and union territories in India. It is an urgent task to survey the fluorosis-related problems in these regions. Objective: To study the clinical manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India. Methods: A cross-sectional study was conducted in

  • Impact of subchronic exposure to triclosan and/or fluoride on estrogenic activity in immature female rats: The expression pattern of calbindin-D9k and estrogen receptor a genes.

    This study explored the influence of triclosan (TCS) in the absence and presence of sodium fluoride (NaF) on estrogenic activity and thyroid function of adolescent female rats. The results indicated that the individual exposure to TCS evoked a significant decline in T3 and T4 but the levels of estradiol, FSH,

  • Fluoride ingestion and thyroid function in children resident of naturally fluoridated areas - An observational study.

    Background: Literature shows association between systemic fluorides with water fluoride level above 3ppm and endocrine disorders especially related to thyroid. Aim & Objectives: To estimate serum T3, T4, TSH, Fluoride levels among children with normal nutritional status and optimal iodine intake, residing in three different ranges of drinking water fluoride levels

  • Role of endoplasmic reticulum stress-induced apoptosis in rat thyroid toxicity caused by excess fluoride and/or iodide

    Excess fluoride and iodide coexist in drinking water in many regions, but few studies have investigated the single or interactive effects on thyroid in vivo. In our study, Wistar rats were exposed to excess fluoride and/or iodide through drinking water for 2 or 8 months. The structure and function of

• Related FAN Content :

  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

  • Fluoride's Impact on Thyroid Hormones

    Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as

  • Mikhailets (1996): Functional state of thyroid under extended exposure to fluorides

    Abnormalities in the thyroid function characterized by a decreased iodine absorption function of the thyroid, a low level T3 syndrome, and a slight increase of the TSH level are observed in cases of chronic fluorine intoxication in the industrial workers.

  • NRC (2006): Fluoride's Impact on the Thyroid Gland

    Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.

  • Fluorine in the Aetiology of Endemic Goitre

    The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.