Abstract
No abstract available.
Note from Fluoride Action Network:
Synonym for Basedow disease is Graves disease
- Toxic goiter characterized by diffuse hyperplasia of the thyroid gland, a form of hyperthyroidism.
- Thyroid dysfunction and all or any of its clinical associations.
- Organ-specific autoimmune disease of thyroid gland.
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Effect of excess fluoride ingestion on human thyroid function in Gaya region, Bihar, India.
Fluoride (F) is mainly ingested through drinking water and food. In addition to producing dental and skeletal fluorosis, excess fluoride may also affect the functioning of many organs including the thyroid gland. The present study investigated the thyroid function of subjects with dental fluorosis from F-endemic areas of Gaya region,
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Epidemiological study of goitre in endemic fluorosis district of Gujarat
Soft tissue fluoride toxicity is well established. Several animal and human studies of the effect of fluoride on the thyroid gland have shown conflicting results. Endemic fluorosis and goitre are widespread in India with considerable overlapping in different geographical zones. We examined 22,276 individuals for presence of goitre and dental
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[A preliminary approach to the relationship of both endemic goiter and fluorosis in the valley of Manasi River, Xin-Jiang to environmental geochemistry].
According to the geographical features of the inland basins and the motion law by which a variety of chemical elements move along the rivers and deposit in the bottom of the basins in Xinjiang,the author made a series of investigations to find out the effects of the factors of environmental
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Study of excess fluoride ingestion and thyroid hormone derangement in relation with different fluoride levels in drinking water among children of Jodhpur District, Rajasthan, India.
The study was carried out in selected villages of Jodhpur district of Rajasthan. Study area was divided into four categories with different fluoride levels in drinking water. Total 100 children aged 8-14 years were screened for dental fluorosis and biochemical analysis. 25 children were selected from each category. The dental
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Absence of DNA damage in multiple organs (blood, liver, kidney, thyroid gland and urinary bladder) after acute fluoride exposure in rats
Fluoride has been widely used in dentistry as a caries prophylactic agent. However, there has been some speculation that excess fluoride could cause an impact on genome integrity. In the current study, the potential DNA damage associated with exposure to fluoride was assessed in cells of blood, liver, kidney, thyroid
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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NRC (2006): Fluoride's Impact on the Thyroid Gland
Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.
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Mikhailets (1996): Functional state of thyroid under extended exposure to fluorides
Abnormalities in the thyroid function characterized by a decreased iodine absorption function of the thyroid, a low level T3 syndrome, and a slight increase of the TSH level are observed in cases of chronic fluorine intoxication in the industrial workers.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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