Goitre and Fluorosis in Kenya

Fluorosis and iodine deficiency disorders in India.

This review focuses on fluorosis and iodine deficiency disorders, two serious, highly prevalent metabolic disorders that are under-reported. These are caused by the two elements of the halogen family, fluorine and iodine. The former in excess and the latter in deficiency are the cause for concern. Excess fluoride (F–) consumption

Synergistic action of iodine-deficiency and fluorine-intoxication on rat thyroid.

212 Wistar rats were divided randomly into five groups, each of which was fed on one of the following regimes: (1) Normal iodine and fluorine; (2) normal iodine, 10 ppm fluorine; (3) normal iodine, 30 ppm fluorine; (4) now iodine, normal fluorine; (5) low iodine, 10 ppm fluorine. The experiment

[Effects of fluoride on thyroid structure in chicks].

Objective: To investigate the effects of fluoride on thyroid structure in chicks. Methods: 250 one day chicks were randomly divided into 5 groups, 50 for each. Group I was the control, and other four groups, group II, III, IV, V were fed the diets containing 500, 1,000, 1,500, 2,000 mg/kg of

Effect of excess fluoride ingestion on human thyroid function in Gaya region, Bihar, India.

Fluoride (F) is mainly ingested through drinking water and food. In addition to producing dental and skeletal fluorosis, excess fluoride may also affect the functioning of many organs including the thyroid gland. The present study investigated the thyroid function of subjects with dental fluorosis from F-endemic areas of Gaya region,

Mikhailets (1996): Functional state of thyroid under extended exposure to fluorides

Abnormalities in the thyroid function characterized by a decreased iodine absorption function of the thyroid, a low level T3 syndrome, and a slight increase of the TSH level are observed in cases of chronic fluorine intoxication in the industrial workers.

Fluoride, Water Hardness, and Endemic Goitre

Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.

Fluoride Exposure Aggravates the Impact of Iodine Deficiency

A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and

Fluoride & Goiter

Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the

NRC (2006): Fluoride's Impact on the Thyroid Gland

Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.