Abstract
No abstract available
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Taurine ameliorates renal oxidative damage and thyroid dysfunction in rats chronically exposed to fluoride
Excessive exposure to fluoride poses several detrimental effects to human health particularly the kidney which is a major organ involved in its elimination from the body. The influence of taurine on fluoride-induced renal toxicity was investigated in a co-exposure paradigm for 45 days using five groups of eight rats each. Group I rats received
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Long-term effects of various iodine and fluorine doses on the thyroid and fluorosis in mice
OBJECTIVE: To elucidate the participation of the independent and combined long term effect of various concentrations of iodine and fluorine on the pathogenesis of goiter and fluorosis in mice. METHODS: Nine drinking water supplies with different iodine and fluorine content were prepared by combination of potassium iodate and sodium fluoride solutions in bidistilled
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Study on serum T4, T3 and TSH levels in patients with chronic skeletal fluorosis
A study on the serum T4, T3, and TSH levels was performed in 27 patients with chronic skeletal fluorosis and the data obtained were compared with those of 20 healthy persons. The results showed that serum T4 in the patients was lower than in the controls and TSH was higher.
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[Indices of the pituitary-thyroid system in residents of cities with various fluorine concentrations in drinking water].
The thyroid 131I consumption, the hypophyseal thyrotropic hormone content and the blood serum total thyroxin and triiodothyronine concentrations were studied in equal groups of healthy humans and donors, living in two cities with an enhanced or decreased fluorine content in drinking water. Iodine deficiency and adaptive amplification of the hypophyseal-thyroid
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Endemic goitre in the absence of iodine deficiency in schoolchildren of the Northern Cape Province of South Africa
OBJECTIVE: The study was undertaken to investigate whether endemic goitre still exists in the Northern Cape Province of South Africa more than 55 years after it was reported and, if so, whether iodine deficiency, or fluoride in the drinking water, is linked to the goitres. DESIGN: Cross-sectional study of children in three pairs
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Mikhailets (1996): Functional state of thyroid under extended exposure to fluorides
Abnormalities in the thyroid function characterized by a decreased iodine absorption function of the thyroid, a low level T3 syndrome, and a slight increase of the TSH level are observed in cases of chronic fluorine intoxication in the industrial workers.
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Is fluoride-induced hyperthyroidism a cause of psychosis among East African immigrants to Scandinavia?
When people with a compensated fluoride-induced hypothyroidism move to a low-fluoride area, the fluoride-induced inhibition of the production of thyroid hormones ceases. In Scandinavia, the dietary intake of iodine is usually quite high due to iodized table salt and easy access to marine fish. Under these conditions, the elevated capacity for production of thyroid hormones may result in hyperthyroidism.
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NRC (2006): Fluoride's Impact on the Thyroid Gland
Several lines of information indicate an effect of fluoride exposure on thyroid function. It is difficult to predict exactly what effects on thyroid function are likely at what concentration of fluoride exposure and under what circumstances.
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Fluoride Exposure Aggravates the Impact of Iodine Deficiency
A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and
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