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  • [Effects of fluoride on the thyroid morphology and thyroid peroxidase and serum thyroid hormones].

    Objective To observe the effects of fluoride on thyroid morphology,thyroid peroxidase and serum thyroid hormones. Methods One - month ablactating SD rats were randomly divided into three groups:the control group, low-fluoride group, middle-fluoride group, high-fluoride group, fed with water containing different fluoride concentration by adding NaF respectively. Rats were sacrificed after

  • y-Aminobutyric acid ameliorates fluoride-induced hypothyroidism in male kunming mice

    AIM:  This study evaluated the protective effects of y-aminobutyric acid (GABA), a non-protein amino acid and anti-oxidant, against fluoride-induced hypothyroidism in mice. MAIN METHODS:  light microscope sample preparation technique and TEM sample preparation technique were used to assay thyroid microstructure and ultrastructure; enzyme immunoassay method was used to assay hormone and

  • Effect of sodium fluoride on the structure and function of the thyroid and ovary in albino rats (Rattus Norvegicus).

    Objective: The objective was to investigate the effect of sodium fluoride (NaF) on the structure and function of the thyroid and ovary in albino rats. Method: Twenty-four female adult albino rats, 160–180 g body weight (bw), were divided into four groups of 6: the control group (I) received defluoridated water while the other

  • Fluorine and thyroid gland function: a review of the literature

    The increasing use of fluoride for prevention of dental caries poses the problem as to whether this halogen has antagonistic properties towards iodine, whereby it could hamper the success of iodine prophylaxis of endemic goitre. Review of the literature shows that some authors have found an inhibition by fluoride of

  • Dental fluorosis, nutritional status, kidney damage, and thyroid function along with bone metabolic indicators in school-going children living in fluoride- affected hilly areas of Doda District, Jammu and Kashmir, India.

    A case-control study was undertaken among the school children aged 8-15 years to know the presence and severity of dental fluorosis, nutrition and kidney status, and thyroid function along with bone metabolic indicators in Doda district situated at high altitude where drinking water was contaminated and heat stress. This study

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  • Fluoride's Impact on Thyroid Hormones

    Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as

  • Is fluoride-induced hyperthyroidism a cause of psychosis among East African immigrants to Scandinavia?

    When people with a compensated fluoride-induced hypothyroidism move to a low-fluoride area, the fluoride-induced inhibition of the production of thyroid hormones ceases. In Scandinavia, the dietary intake of iodine is usually quite high due to iodized table salt and easy access to marine fish. Under these conditions, the elevated capacity for production of thyroid hormones may result in hyperthyroidism.

  • Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake

    Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.

  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

  • Fluoride Exposure Aggravates the Impact of Iodine Deficiency

    A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and