Abstract
The study was conducted on 25 healthy women residing in optimum fluoride areas, who were to deliver normally through vaginal route, to correlate the maternal and cord plasma fluoride levels and evaluate the placental transfer of fluoride. A wide variation was found in the maternal and cord plasma fluoride levels. In only 8 percent of the cases the fluoride levels in cord plasma were higher than maternal plasma. It was deduced that the placenta allows passive diffusion of fluoride from mother to foetus and does not act as a barrier.
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The relationship between human ionic plasma fluoride and serum creatinine concentrations in cases of renal and cardiac insufficiency in a fluoridated community
Previous studies have shown that renal and cardiac insufficiency cause an elevation of ionic plasma fluoride (IPF) concentration in patients suffering from these diseases. The relationship between serum or plasma fluoride concentration and the degree of renal impairment has been tested only twice; with somewhat contrasting results, although some previous
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Pharmacokinetics of fluoride in human adults: The effect of exercise.
Highlights This human study adds to understanding of the effects of exercise on fluoride (F) metabolism. F pharmacokinetics following no, light, moderate and vigorous exercise were compared in adults. Moderate exercise resulted in the highest maximum plasma F concentration (Cmax). Area Under the Curve for plasma F concentration against
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Diagnosis of fluorosis and recovery through easy to practise interventions.
The objectives of the present study were to highlight (i) how to diagnose fluorosis, due to fluoride ion (F) toxicity, in out-patient departments, by retrieving the history and through tests and (ii) the interventions available for recovery. In patients suspected of fluorosis, the F levels were investigated in samples of
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Effect of Long-Term Administration of Sodium Fluoride on Plasma Calcium Level in Relation to Intestinal Absorption and Urinary Excretion in Rabbits.
The present study was undertaken to determine the effect of chronic fluoride toxicity on calcium metabolism. Rabbits (n = 10) were orally administered an aqueous solution of 10 mg NaF/kg body wt daily for 18 months. Equal numbers (n = 10) of age-, sex- and weight-matched rabbits kept under identical
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The association between fluoride in water and blood pressure in children and adolescents.
Background The objective of this study was to determine the association between water and plasma fluoride and blood pressure (BP) among children and adolescents. Methods Our study population was individuals of 8–18 years in the 2013–2016 National Health and Nutrition Examination Survey. We performed a multivariable linear and logistic regression analysis to examine
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