Transplacental passage of fluorides was studied in 25 randomly selected neonates. Blood samples collected simultaneously from the mother and the umbilical cord showed that average fluoride concentration in the cord blood was 60% of that in mother’s blood. When concentration in the mother’s blood exceeded 0.4 ppm, the placenta acted as a selective barrier.
Fluoride exposure and sleep patterns among older adolescents in the United States: a cross-sectional study of NHANES 2015–2016.
Abstract Background Fluoride from environmental sources accumulates preferentially in the pineal gland which produces melatonin, the hormone that regulates the sleep-wake cycle. However, the effects of fluoride on sleep regulation remain unknown. This population-based study examined whether chronic low-level fluoride exposure is associated with sleep patterns and daytime sleepiness among older adolescents
Elemental Status and Lipid Peroxidation in the Blood of Children With Endemic Fluorosis
The study aimed to assess the levels of trace elements, minerals, and toxic elements as well as lipid peroxidation biomarkers (lipid acyl hydroperoxides, 2-thiobarbituric acid reactive substances (TBARS)) in the blood of children with chronic fluorosis from endemic fluorosis areas (Sosnivka village, Lviv region, western Ukraine). The results were compared
Serum inorganic fluoride: changes related to previous fluoride intake, renal function and bone resorption
1. Inorganic fluoride concentrations were determined in serum and urine specimens of 24 subjects receiving a standardized low fluoride intake. Serum fluoride was directly correlated with previous intake and appeared to reflect bone fluoride stores. 2. A positive correlation between creatinine and fluoride clearance was found. However, striking reductions in
Biochemistry of Fluorosis X - Comparative Study of the Fluoride Levels in Biological Fluids.
The fluoride content of drinking water is directly correlated with the serum and saliva fluoride. Serum fluoride levels are also directly related to those of saliva, but not to urinary fluoride. These interrelations are so close that a mathematical formula can be devised for the calculation of fluoride in body fluids.
Serum fluoride concentrations in renal insufficiency
In an area with non-fluoridated water (F content, 0.061 ppm), serum fluoride concentrations as measured with an ion specific electrode were as follows: controls (N = 13), 0.0127 ppm + 0.0057 (mean + SD); renal insufficiency (N = 10), 0.0452 ppm + 0.0151; chronic hemodialysis (N = 11), 0.0424 +
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