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  • Combination of fluoride and endosulfan induced teratogenicity and developmental toxicity in Swiss albino mice exposed during organogenesis.

    The present investigation was conducted to evaluate the teratogenic and developmental toxicity of fluoride and endosulfan alone and in combination in pregnant Swiss albino mice exposed during the organogenetic period (5-14 days) of gestation. Fluoride (25.1 mg/kg body weight in water) and endosulfan (1.8 mg/kg bw by oral intubation) when

  • Potentials for developmental fluoride neurotoxicity

    The foetus and the child are particularly vulnerable to pollution. The foetus shares the mother’s exposure and accumulated body burden of pollutants, and some chemicals are transferred to the infant via human milk. Occurrence of severe dental fluorosis in a child, whose mother had worked at the Danish cryolite factory

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    Fluoride exposure is an important public health problem in several Mexican states. In the city of San Luis Potosi, Mexico, above 90% of the children have some degree of dental fluorosis. The main source of exposure to fluoride is tap water. The objective of the study was to evaluate the

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    We have attempted to suppress voltage-dependent conductances in hippocampal neurons by introducing various intracellular agents. Voltage-clamp studies were carried out using acutely dissociated hippocampal neurons from adult guinea pigs. Synaptic events were examined using intracellular recordings in the slice preparation. Sodium conductance was suppressed when the quaternary lidocaine derivative QX

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