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Black tea extract mitigation of NaF-induced lipid peroxidation in different regions of mice brains.
SUMMARY: As part of our investigation of fluoride toxicity effects in a group of 80 Swiss albino adult male mice, we examined the mitigating effects of black tea extract (BTE) on the F-induced enzymatic and non-enzymatic parameters of oxidative stress in the cerebral hemisphere (CH), cerebellum (CB), and medulla oblongata (MO) of the
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Effect of fluoride on the microglial morphology and the expression of inflammatory cytokines in the cerebral cortex of mice.
To investigate the effects of fluoride exposure on the microglialmorphology and the expression of inflammatory cytokines in the cerebral cortex of mice, thirty-six ICR male mice were randomly divided into groups and given different doses of sodium fluoride (0, 25, and 50 mg/L NaF). After 50 days, the microglialmorphology and
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Alterations in plasma and tissue acetylcholinesterase activity following repeated oral exposure of chlorpyrifos alone and in conjunction with fluoride in Wistar Rats
Concurrent exposures of more than one environmental contaminants are commonly encountered by human beings and animals. This study investigated the effect of chlorpyrifos alone and in conjunction with fluoride on plasma and tissue acetylcholinesterase (AChE) activity in wistar rats. Fluoride at 1 or 10 ppm in drinking water produced significant (P < 0.05)
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Symposium on the non-skeletal phase of chronic fluorosis: The spinal cord
The author presents evidence of damage to the spinal cord in skeletal fluorosis. Since pressure on the cord by osteophytes was ruled out, direct action of fluoride on cord tissue is likely to be responsible for this condition. Neurological complications of skeletal fluorosis have been described in endemic areas, especially in
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Study on the correlation between daily total fluoride intake and children’s intelligence quotient.
Objective: To explore the exact relationship between daily total intake of fluoride and children's intelligence quotient (IQ). Methods: Wamiao village (severely endemic fluorosis area, drinking water fluoirde was 0.57-4.50 mgL) and Hinhuai village (non-endemic fluorosis area, drinking water fluoride was 0.18-0.76 mgL-1) in Shong County, Jiangsu Province, were selected for this
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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Fluoride & IQ: 76 Studies
Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies
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