Extract

Like the skin and its appendages, the teeth, nails and hair, so also other tissues of ectodermal origin are here shown to be affected by fluorine. The action of fluorine consists in lowering the level of the calcium in the blood and tissues. The epithelia of the mouth and the salivary glands, of the nasopharynx, the conjunctivae and the lachrymal glands may be affected. Signs and symptoms are thus produced which are closely similar to those usually attributed primarily to infection. It is suggested that an infection accompanying chronic fluorine poisoning is of a secondary nature, and that it is brought about by the loss of calcium in the body.

References

Ainsworth, N. J. (1933). Brit. Dent. J. 55, 233. Google Scholar

Broekema, J. H. (1933). Acta derm.-venereol., Stockh., 14, 113. Google Scholar

Dean, H. T. (1936). J. Amer. Med. Ass. 107, 1269. CrossRef | Google Scholar

Dean, H. T. & Elvove, E. (1936). Amer. J. Publ. Hlth, 26, 567. CrossRef | Google Scholar

Erdheim, J. (1906). Mitt. Grenzgeb. Med. Chir. 16, 632. Google Scholar

Friedmann, M. (1921). Arch. Derm. Syph., Berlin, 135, 161. CrossRef | Google Scholar

Gaud, Charnot & Langlais, (1935). Odontologie, 73, 188. Google Scholar

Gilford, H. (1904). Practitioner, 73, 188. Google Scholar

Goeckermann, W. H. (1920). Arch. Derm. Syph., Chicago, 1, 396. CrossRef | Google Scholar

Hill, A. M. (1933). Arch. Derm. Syph., Chicago, 28, 66. CrossRef | Google Scholar

Jacobsen, A. W. (1928). J. Amer. Med. Ass. 90, 686. CrossRef | Google Scholar

Josephson, E. M. & Lerner, C. (1934). Arch. Derm. Syph., Chicago, 29, 703. CrossRef | Google Scholar

Kaznelson, P., Reimann, F. & Weiner, W. (1929). Klin. Wschr. 81, 1071. CrossRef | Google Scholar

Lachmann, A. (1941). Acta Med. Scand., Suppl. 121. Google Scholar

McEwen, E. L. (1916). J. Cutan. Dis. 34, 15. Google Scholar

MacKee, G. M. & Andrews, G. C. (1924). Arch. Derm. Syph., Chicago, 10, 673. CrossRef | Google Scholar

Mendes da Costa, S. & Van der Valk, J. W. (1919). Urol. Cutan. Rev. 23, 159. Google Scholar

Nicolle, G. & Halipré, A. (1895). Ann. Derm. Syph., Paris, 6, 675, 804. Google Scholar

Spira, L. (1928). Franco-Brit. Med. Rev. 5, 1, 61. Google Scholar

Spira, L. (1933). The Clinical Aspect of Chronic Poisoning by Aluminium and its Alloys. London. Google Scholar

Spira, L. (1942 a). Edinb. Med. J. 49, 707. Google Scholar

Spira, L. (1942 b). J. Hyg., Camb., 42, 500. CrossRef | Google Scholar

Spira, L. (1943 a). J. Hyg., Camb., 43, 69. CrossRef | Google Scholar

Spira, L. (1943 b). To be published. Google Scholar

Spira, L. (1943 c). Edinb. Med. J. 50, 237. Google Scholar

Thurnam, J. (1848). Proc. Roy. Med. Chir. Soc. 31, 71. CrossRef | Google Scholar

Weech, A. A. (1929). Amer. J. Dis. Child. 37, 766. CrossRef | Google Scholar

Wenner, W. F. (1931). J. Lab. Clin. Med. 16, 341. Google Scholar

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