Extract
Like the skin and its appendages, the teeth, nails and hair, so also other tissues of ectodermal origin are here shown to be affected by fluorine. The action of fluorine consists in lowering the level of the calcium in the blood and tissues. The epithelia of the mouth and the salivary glands, of the nasopharynx, the conjunctivae and the lachrymal glands may be affected. Signs and symptoms are thus produced which are closely similar to those usually attributed primarily to infection. It is suggested that an infection accompanying chronic fluorine poisoning is of a secondary nature, and that it is brought about by the loss of calcium in the body.
References
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Ainsworth, N. J. (1933). Brit. Dent. J. 55, 233. Google ScholarBroekema, J. H. (1933). Acta derm.-venereol., Stockh., 14, 113. Google ScholarDean, H. T. (1936). J. Amer. Med. Ass. 107, 1269. CrossRef | Google ScholarDean, H. T. & Elvove, E. (1936). Amer. J. Publ. Hlth, 26, 567. CrossRef | Google ScholarErdheim, J. (1906). Mitt. Grenzgeb. Med. Chir. 16, 632. Google ScholarFriedmann, M. (1921). Arch. Derm. Syph., Berlin, 135, 161. CrossRef | Google ScholarGaud, Charnot & Langlais, (1935). Odontologie, 73, 188. Google ScholarGilford, H. (1904). Practitioner, 73, 188. Google ScholarGoeckermann, W. H. (1920). Arch. Derm. Syph., Chicago, 1, 396. CrossRef | Google ScholarHill, A. M. (1933). Arch. Derm. Syph., Chicago, 28, 66. CrossRef | Google ScholarJacobsen, A. W. (1928). J. Amer. Med. Ass. 90, 686. CrossRef | Google ScholarJosephson, E. M. & Lerner, C. (1934). Arch. Derm. Syph., Chicago, 29, 703. CrossRef | Google ScholarKaznelson, P., Reimann, F. & Weiner, W. (1929). Klin. Wschr. 81, 1071. CrossRef | Google ScholarLachmann, A. (1941). Acta Med. Scand., Suppl. 121. Google ScholarMcEwen, E. L. (1916). J. Cutan. Dis. 34, 15. Google ScholarMacKee, G. M. & Andrews, G. C. (1924). Arch. Derm. Syph., Chicago, 10, 673. CrossRef | Google ScholarMendes da Costa, S. & Van der Valk, J. W. (1919). Urol. Cutan. Rev. 23, 159. Google ScholarNicolle, G. & Halipré, A. (1895). Ann. Derm. Syph., Paris, 6, 675, 804. Google ScholarSpira, L. (1928). Franco-Brit. Med. Rev. 5, 1, 61. Google ScholarSpira, L. (1933). The Clinical Aspect of Chronic Poisoning by Aluminium and its Alloys. London. Google ScholarSpira, L. (1942 a). Edinb. Med. J. 49, 707. Google ScholarSpira, L. (1942 b). J. Hyg., Camb., 42, 500. CrossRef | Google ScholarSpira, L. (1943 a). J. Hyg., Camb., 43, 69. CrossRef | Google ScholarSpira, L. (1943 b). To be published. Google ScholarSpira, L. (1943 c). Edinb. Med. J. 50, 237. Google ScholarThurnam, J. (1848). Proc. Roy. Med. Chir. Soc. 31, 71. CrossRef | Google ScholarWeech, A. A. (1929). Amer. J. Dis. Child. 37, 766. CrossRef | Google ScholarWenner, W. F. (1931). J. Lab. Clin. Med. 16, 341. Google Scholar
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Calcium deficiency in fluoride-treated osteoporotic patients despite calcium supplementation
To test the hypothesis that the osteogenic response to fluoride can increase the skeletal requirement for calcium, resulting in a general state of calcium deficiency and secondary hyperparathyroidism, we assessed calcium deficiency, spinal bone density, by quantitative computed tomography, and serum PTH in three groups of osteoporotic subjects. Two of
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Endemic chronic fluoride toxicity and dietary calcium deficiency interaction syndromes of metabolic bone disease and deformities in India: year 2000
Epidemiological studies during 1963-1997 were conducted in 45,725 children exposed to high intake of endemic fluoride in the drinking water since their birth. Children with adequate (dietary calcium > 800 mg/d) and inadequate (dietary calcium < 300 mg/d) calcium nutrition and with comparable intakes of fluoride (mean 9.5 +/- 1.9
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The association of fluoride in drinking water with serum calcium, vitamin D and parathyroid hormone in pregnant women and newborn infants.
Background: Chronic exposure to fluoride in drinking water causes an increase in plasma fluoride levels that is related to a reduction in calcium transport across the renal tubule endoplasmic reticulum and plasma membrane. In the present study, it was hypothesised that varying levels of fluoride present in drinking
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[Effects of excess fluoride on bone turnover under conditions of diet with different calcium contents].
OBJECTIVE: To study the effects of excess fluoride on bone turnover under conditions of diet containing different amount of calcium. METHODS: The experiment was performed on rats raised on a balanced diet with adequate calcium or a monotonous diet with low calcium and given amount of fluoride in their drinking water
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Effects of estrogen on bone composition in rats at low and high fluoride intake
Bone examinations were carried out on female rats which had received estradiol benzoate and drinking water containing either 0.55 or 50 ppm of fluoride (F). The estradiol benzoate was injected subcutaneously twice weekly and the rats were killed after 2, 4 and 6 weeks. The results showed that estrogen treatment
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Nutrient Deficiencies Enhance Fluoride Toxicity
It has been known since the 1930s that poor nutrition enhances the toxicity of fluoride. As discussed below, nutrient deficiencies have been specifically linked to increased susceptibility to fluoride-induced tooth damage (dental fluorosis), bone damage (osteomalacia), neurotoxicity (reduced intelligence), and mutagenicity. The nutrients of primary importance appear to be calcium,
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Skeletal Fluorosis & Individual Variability
One of the common fallacies in the research on skeletal fluorosis is the notion that there is a uniform level of fluoride that is safe for everyone in the population. These "safety thresholds" have been expressed in terms of (a) bone fluoride content, (b) daily dose, (c) water fluoride level, (d) urinary fluoride level, and (e) blood fluoride level. The central fallacy with each of these alleged safety thresholds, however, is that they ignore the wide range of individual susceptibility in how people respond to toxic substances, including fluoride.
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel
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Fluoride Exposure Increases Metabolic Requirement for Calcium & Vitamin D
It is well known that individuals with nutrient deficiencies are more susceptible to fluoride toxicity, including fluoride's bone effects. As discussed in the following studies, fluoride increases the skeleton's need for calcium (and vitamin D) by increasing the amount of unmineralized tissue (osteoid) in the bone. When insufficient calcium and
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Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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