Forty male students were each exposed on two occasions to four hours of inhalation of either air or 500 ppm nitrous oxide with or without 15 ppm halothane in air. Immediately following exposure, a battery of tests of perceptual, cognitive and motor skills was administered. Compared with responses after breathing of air, those after exposure to nitrous oxide and halothane showed significant decrements in performances of a task in which attention was divided between auditory and visual signals, a visual tachistoscopic test, and memory tests involving digit span and recall of word pairs. Subjects exposed to nitrous oxide alone scored
significantly lower on the digit-span test only.
(Key words: Anesthetics, Volatile: halothane; Anesthetics, gases: nitrous oxide; Psychologic function.)
1. Linde HV, Bruce DL: Occupational exposure of anesthetists to halothane. nitrous oxide and radiation. Anesthesiology 30:363-368, 1969.
2. Corbett TH: Retention of anesthetic agents following occupational exposure. Anestl, Analg (Cleve) 52:614-Gli, 1973.
3. Salvini M, Binaschi S, Riva M: Evaluation of the psychophysiological functions in humans exposed to trichloroethylene. Br J Ind Med 28:293-295, 1971.
4. Bruce DL: A simple way to vent anesthetic gases. Anesth Analg (Cleve) 52:595-598, 197.3
Effect of Fluoride Concentration in Drinking Water on Intelligence Quotient of 12-14-Year-Old Children in Mathura District: A Cross-Sectional Study.
Aims: The aim was to assess and correlate the influence of the concentration of fluoride in ingested water on the intelligence quotient (IQ) of 12–14-year-old youngsters in Mathura district. Materials and Methods: A total of 219 children were selected, 75 from low F area, 75 medium F area, and 69 from
Investigation on children’s growth and development under long-term fluoride exposure
Objective To study the influence on children’s growth by long-term high fluoride exposure. Methods Case group was selected in high fluoride areas and control group was selected in non-high fluoride areas. The difference of children’s growth levels were analyzed between 2 groups. Results The IQ of case group was significantly lower than that of control
Effect of fluorosis on mice learning and memory behaviors and brain SOD activity and MDA content
Objective: Explore the brain mechanism of the effect of fluorosis on learning and memory behavior. Method: A method combining behavioral observation and biochemical testing was used to study the effects of long-term drinking different concentrations of sodium fluoride on mouse learning and memory behavior and changes in content of brain
Blood lead of children in Wamiao-Xinhuai intelligence study (Letter).
As an additional part of our investigation of an association between fluoride in drinking water and children’s intelligence in two villages of Sihong County, Jiangsu Province, China, we have now determined blood lead levels of children in that study. Blood samples (80 ?L) were collected on June 18 and 19, 2003
Fluoride exposure and reported learning disability diagnosis among Canadian children: Implications for community water fluoridation.
OBJECTIVES: Recent studies have connected increased fluoride exposure with increased risk of neurodevelopmental-related outcomes, such as ADHD (attention deficit hyperactivity disorder) and lower IQ in children. Our primary objective was to examine the association between fluoride exposure and reported diagnosis of a learning disability among a population-based sample of Canadian
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
Fluoride & IQ: 68 Studies
As of February 2021, a total of 76 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 68 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or
Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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