Abstract
Introduction
High groundwater fluoride (F) is one of the major environmental hazards in the dry zone of Sri Lanka. The prolonged exposure to F at maximum contaminant levels can give rise to lifelong debility and disability among its inhabitants.
Objective
This study investigated the F contamination in groundwater resources in Sri Lanka above recommended Maximum Contaminant Levels (MCL) and possibilities to mitigate the health risk.
Methods
Groundwater samples (6107) were randomly collected from different geographic areas of the country, and categorised as hazardous, if it exceeded the maximum contaminant level of 4 mg/L (the level at which bone health is compromised). The minimum distances from a hazardous to a relatively safe F groundwater source (below 1.0 mg/L and 1.5 mg/L) were determined using geospatial analysis.
Results: Only 2.3% (142) of the total sample was found to be hazardous to skeletal health. Optimal F sources were identified in close proximity to highly contaminated sources (>4.0 mg/L), some even within a walking distance of 500 metres.
Conclusion
The identification and elimination of maximally contaminated sources, possibly by dilution with widely available low F sources in close proximity, would be a more feasible and cost effective approach to ensure long term public health benefits.
*Original abstract online at https://cmj.sljol.info/articles/abstract/10.4038/cmj.v63i4.8768/
-
-
The impact of developmental defects of enamel on young people in the UK
OBJECTIVES: To explore the impact of developmental defects of enamel (DDE) on young people, through their experiences of the condition and it's meaning to their everyday lives. METHODS: The theoretical framework chosen to guide the study was symbolic interactionism. Qualitative interviews with a purposive sample of people aged 10-15 years
-
Role of Wnt/B-catenin signaling pathway in ameloblast differentiation in relevance to dental fluorosis.
Excess consumption of fluoride during the development of tooth enamel will cause dental fluorosis, but the exact molecular mechanisms remain to be elucidated. Circadian rhythm is implicated in many physiological processes and various diseases. There is increasing evidence indicates that ameloblast differentiation is under the control of clock genes. However, it has not been reported
-
JNK Signaling Pathway Mediates Fluoride-Induced Upregulation of CK1a during Enamel Formation.
Fluorosis is a defect in the enamel mineral content caused by excessive fluoride intake during amelogenesis; the interaction of various factors in the development and progression of fluorosis has not been defined. Casein kinase 1a (CK1a) is constitutively active in cells and is involved in diverse cellular processes; however, its
-
Prevalence of dental fluorosis and treatment needs among 11-14 years old school children in endemic fluoride areas of Haryana, India.
Introduction: Dental fluorosis is a major endemic oral disease characterized by hypo mineralization of enamel caused due to consumption of water containing high concentration of fluoride during developmental stages of teeth. Aim: To assess the prevalence of dental fluorosis among 11-14 years old school children in endemic
-
Equine dental and skeletal fluorosis induced by well water consumption.
Two horses that consumed well water with high fluoride content exhibited clinical signs of chronic dental and skeletal fluoride toxicosis and were later euthanized and autopsied. Both horses had degenerative disease of multiple joints and multiple dental defects. Elevated fluoride concentrations were found in bone and tooth samples of both
Related Studies :
-
-
-
Community Fluorosis Index (CFI)
The current Community Fluorosis Index for U.S. adolescents as a whole (from both fluoridated and non-fluoridated areas) is roughly 5 times higher than the CFI health authorities predicted for fluoridated areas when fluoridation first began. It is also higher than the CFI that the NIDR found in fluoridated areas back in the 1980s. It is readily apparent, therefore, that children are ingesting far more fluoride than was the case in the 1950s, and even as recently as the 1980s.
-
Diagnostic Criteria for Dental Fluorosis: The TSIF ("Total Surface Index of Fluorosis")
The traditional criteria (the "Dean Index") for diagnosing dental fluorosis was developed in the first half of the 20th century by H. Trendley Dean. While the Dean Index is still widely used in surveys of fluorosis -- including the CDC's national surveys of fluorosis in the United States -- dental
-
Dental Fluorosis: The "Cosmetic" Factor
Any condition that can cause children to be embarrassed about their physical appearance can have significant consequences on their self-esteem and confidence. Researchers have repeatedly found that "physical appearance [is] the best predictor of self-esteem" in adolescents, (Harter 2000) and that facial attractiveness, particularly the appearance of one's teeth, is a
-
Dental Fluorosis Impacts Dentin in Addition to Enamel
Dental fluorosis is a mineralization defect of tooth enamel marked by increased subsurface porosity. The enamel, however, is not the only component of teeth that is effected. As several studies have demonstrated, dental fluorosis can also impair the mineralization of dentin as well. As noted in one review: "The fact that
-
Dental Fluorosis Is a "Hypo-mineralization" of Enamel
Teeth with fluorosis have an increase in porosity in the subsurface enamel ("hypomineralization"). The increased porosity of enamel found in fluorosis is a result of a fluoride-induced impairment in the clearance of proteins (amelogenins) from the developing teeth. Despite over 50 years of research, the exact mechanism by which fluoride impairs amelogin
Related FAN Content :
-