Friday, January 19th, 2018

Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity.

from 4. Discussion … In order to gain a better understanding of the NaF neurotoxicity and its underlying mechanisms, the NaF-treated rats and SH-SY5Y cells were used in the present study. The MWM [Morris water maze test] results showed that exposure of rats to NaF is associated with decreased learning and memory abilities. This is […]

Friday, February 5th, 2016

Excessive apoptosis and defective autophagy contribute to developmental testicular toxicity induced by fluoride

Thursday, March 27th, 2014

ER-stress caused by accumulated intracistanal granules activates autophagy through a different signal pathway from unfolded protein response in exocrine pancreas cells of rats exposed to fluoride.

Sunday, March 9th, 2014

Sirtuin1 and autophagy protect cells from fluoride-induced cell stress