Tag: Genotoxicity
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Genotoxicity of spent pot liner as determined with the zebrafish (Danio rerio) experimental model.
References AL-SABTI K, METCALFE CD (1995) Fish micronuclei for assessing genotoxicity in water. Mutation Res Genetic Toxicology 343(2):121–135. https://doi.org/10.1016/0165-1218(95)90078-0 CAS Article Google Scholar ANDRADE LF, CAMPOS JMS, DAVIDE LC (2008) Cytogenetic alterations induced by SPL (spent pot liner) in meristematic cells of plant bioassays. Ecotoxicol Environ Saf 71(3):706–710. https://doi.org/10.1016/j.ecoenv.2008.02.018 CAS Article Google Scholar ANDRADE LF, […]
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Cytotoxicity, genotoxicity, and cellular metal accumulation caused by professionally applied fluoride products in patients with fixed orthodontic appliances: A randomized clinical trial.
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European Commission: SCHER 2010 report on fluoridation; Opinions-Layman, Level 3
Level 3 at https://ec.europa.eu/health/scientific_committees/opinions_layman/fluoridation/en/l-3/index.htm#0 The texts in Level 3 are directy quoted from: Source & ©: SCHER Critical review of any new evidence on the hazard profile, health effects, and human exposure to fluoride and the fluoridating agents of drinking water More… 1 Introduction Background Fluoride is not considered to be essential for human growth […]
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Toxicity and effect of whitening toothpastes on enamel surface.
Abstract This in vitro study evaluated the biocompatibility and abrasivity of whitening and conventional toothpastes. Samples of conventional (non-whitening) – Edel White Infant (EWI) – and whitening toothpastes – Edel White Whitening (EWW), Edel White CAREFORTE (EWC), Colgate Total 12 Ò Professional (C), and Oral-B Whitening (OB) – were dissolved in culture medium (0.2 g […]
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Genotoxicity of fluoride subacute exposure in rats and selenium intervention.
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Investigation of the genotoxic effects of fluoride on a bone tissue model .
References Lav KH, Baylink DJ (1998) Molecular mechanism of action of fluoride on bone cells. J Bone Miner Res 13:1660–1667 Article Google Scholar Perumal E, Paul V, Govindarajan V, Panneerselvam L (2013) A brief review on experimental fluorosis. Toxicol Lett 223:236–251 CAS Article Google Scholar Purohit SD, Gupta RC, Mathur AK, Gupta N, Jeswani ID, […]
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Health Effects of Ingested Fluoride
Excerpts: INTRODUCTION Fluoridation of drinking water has been a subject of controversy for decades. Over the past 50 years, the incidence of dental caries (cavities) has declined considerably in the United States, an important health advance that most scientists attribute principally to increased access to fluoridated water and dental products. According to the U.S. Centers […]
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Fluoride in Drinking Water: A Scientific Review of EPA’s Standards.
Excerpts: Summary Under the Safe Drinking Water Act, the U.S. Environmental Protection Agency (EPA) is required to establish exposure standards for contaminants in public drinking-water systems that might cause any adverse effects on human health. These standards include the maximum contaminant level goal (MCLG), the maximum contaminant level (MCL), and the secondary maximum contaminant level […]
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Fluoride- and electromagnetic radiation-induced genotoxicity and impaired melatonin secretion.
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Genotoxic evaluation of sodium fluoride and sodium perborate in mouse bone marrow cells
The LD50 was obtained as the geometric mean of the determined experimental data on mice lethality. The value for sodium fluoride was 32 mg/kg and for sodium perborate the result was 775 mg/kg. The results concerning the SCE rate induced by sodium fluoride are shown in Table 1. Although no significant increase was observed with […]