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Benzotrifluoride. 1987 Fact Sheet by National Toxicology Program.


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NTP CHEMICAL REPOSITORY

BENZOTRIFLUORIDE

*USES: Used in dye chemistry; in the manufacturing of substituted benzotrifluorides containing an ethylenic group; used in high polymer chemistry; in dielectric fluids, such as transformer oils; vulcanizing agent; insecticide.

-IDENTIFIERS

===========

*CATALOG ID NUMBER: 001987

*CAS NUMBER: 98-08-8

*BASE CHEMICAL NAME: BENZOTRIFLUORIDE

*PRIMARY NAME: BENZOTRIFLUORIDE

*CHEMICAL FORMULA: C7H5F3

*STRUCTURAL FORMULA:

*WLN: Not available

*SYNONYMS:

ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE

BENZENYL FLUORIDE

BENZYLIDYNE FLUORIDE

OMEGA-TRIFLUOROTOLUENE

OPHENYLFLUOROFORM

PHENYFLUOROFORM

(TRIFLUOROMETHYL)BENZENE

UN2338

USAF MA-16

-PHYSICAL CHEMICAL DATA

======================

*PHYSICAL DESCRIPTION:

LITERATURE: Water-white liquid

REPOSITORY: Clear colorless liquid

*MOLECULAR WEIGHT: 146.12

*SPECIFIC GRAVITY: 1.1812 @ 25/4 C

*DENSITY: 1.199 g/mL

*MP (DEG C): -29.1 C

*BP (DEG C): 98-99 C

*SOLUBILITIES:

WATER : <1 mg/mL @ 21 C (RAD)

DMSO : >=100 mg/mL @ 21 C (RAD)

95% ETHANOL : >=100 mg/mL @ 21 C (RAD)

METHANOL : Not available

ACETONE : >=100 mg/mL @ 21 C (RAD)

TOLUENE : Not available

OTHER SOLVENTS:

Carbon tetrachloride: Miscible

n-Heptane: Miscible

ETHER : Soluble

BENZENE: Soluble

*VOLATILITY:

Vapor pressure: 11 mm Hg @ 0 C

Vapor density : 5.04

*FLAMMABILITY(FLASH POINT):

This chemical has a flash point of 12.2 C (54 F). It is flammable. Fires involving this material can be controlled with a dry chemical, carbon dioxide, or a Halon extinguisher.

*UEL: Not available

LEL: Not available

*REACTIVITY: This compound may react with oxidizing materials, strong bases and reducing agents.

*STABILITY: This chemical is stable under normal laboratory conditions. UV spectro- photometric stability screening indicates that solutions of the chemical in ethanol are stable for at least 24 hours (RAD).

*OTHER PHYSICAL DATA: Refractive index: 1.4146 @ 20 C Aromatic odor Tolerence (as F) 2.5 mg per cubic meter of air Boiling point: 10 C @ 10 mm Hg

-TOXICITY ========

*NIOSH REGISTRY NUMBER: XT9450000

*TOXICITY: (abbreviations)

typ. dose mode specie amount units other LD50 orl rat 15000 mg/kg LC50 ihl rat 70810 mg/m3/4H LD50 orl mus 10000 mg/kg LC50 ihl mus 92240 mg/m3/2H LD50 ipr mus 100 mg/kg LDLo scu frg 870 mg/kg

*AQTX/TLM96: Not available

*SAX TOXICITY EVALUATION:

THR = HIGH intraperitoneal; MODERATE subcutaneous; LOW oral.

*CARCINOGENICITY: Not available

*MUTATION DATA: Not available

*TERATOGENICITY: Not available

*STANDARDS, REGULATIONS & RECOMMENDATIONS:

OSHA: None

ACGIH: None

NIOSH Criteria Document: None

NFPA Hazard Rating: Health (H): None Flammability (F): None Reactivity (R): None

*OTHER TOXICITY DATA:

Standards and Regulations: DOT-IMO: Flammable liquid; Label: Flammable liquid Status: Reported in EPA TSCA Inventory, 1983 Meets criteria for proposed OSHA Medical Records Rule -OTHER DATA (Regulatory) =======================

*PROPER SHIPPING NAME (IATA):

Benzotrifluoride

*UN/ID NUMBER: UN2338

*HAZARD CLASS: 3 SUBSIDIARY RISK: None PACKING GROUP: II

*LABELS REQUIRED: Flammable liquid

*PACKAGING: PASSENGER: PKG. INSTR.: 305, Y305 MAXIMUM QUANTITY: 5 L, 1 L

CARGO : PKG. INSTR.: 307 MAXIMUM QUANTITY: 60 L

*SPECIAL PROVISIONS: None

*USES: Used in dye chemistry; in the manufacturing of substituted benzotrifluorides containing an ethylenic group; used in high polymer chemistry; in dielectric fluids, such as transformer oils; vulcanizing agent; insecticide.

-HANDLING PROCEDURES

===================

*ACUTE/CHRONIC HAZARDS: When heated to decomposition, this compound emits toxic fumes. It is toxic by inhalation and skin contact. It is extremely corrosive to tissues.

*MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

*RECOMMENDED GLOVE MATERIALS: Recommended Glove Type For Use With Neat (Undiluted) Chemicals: Recommendations based on permeation test results, are made for handling the neat (undiluted) chemical. If this chemical makes direct contact with your glove, or if a tear, puncture or hole develops, replace them at once. Suggested Glove Type(s) (RAD): No information available

*RECOMMENDED RESPIRATOR: When working with this chemical, wear a NIOSH-approved full face chemical cartride respirator equipped with the appropriate organic vapor cartridges. If that is not available, a half face respirator similarly equipped plus airtight goggles can be substituted. However, please note that half face respirators provide a substantially lower level of protection than do full face respirators.

*STORAGE PRECAUTIONS: You should store this chemical in an explosion-proof refrigerator and keep it away from oxidizing materials. STORE AWAY FROM SOURCES OF IGNITION.

*SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

*DISPOSAL AND WASTE TREATMENT: Not available

*OTHER: Not available

-EMERGENCY PROCEDURES

====================

*SKIN CONTACT: IMMEDIATELY flood affected skin with wate

r while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.

IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

*INHALATION:

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.

Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Respirator Recommendation.

*EYE CONTACT:

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.

IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

*INGESTION:

DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting. Thus, the risk of increasing the medical problems by inducing vomiting of a volatile corrosive chemical is very high.

If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital.

If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

*SYMPTOMS:

This comound is extremely destructive to the mucous membranes, upper respiratory tract, skin and eyes. Inhalation may be fatal as a result of spasm, inflammation and edema of the larynx and bronchi; chemical pneumonitis and pulmonary edema. Other symptoms include a burning sensation, coughing, wheezing, laryngitis, shortness of breath; headache, nausea and vomiting.

-SOURCES

=======

*SOURCES:

Lenga, Robert E. The Sigma-Aldrich Library of Chemical Safety Data. Edition 1. Sigma-Aldrich Corporation. Milwaukee, WI. 1985. p. 1770-B.

Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects of Chemical Substances. Microfiche Ed. National Institute for Occupational Safety and Health. Cincinnati, OH. Quarterly Updates. XT9450000.

Weast, R.C., M.J. Astle, and W.H. Beyer, Eds. CRC Handbook of Chemistry and Physics. 65th Ed. CRC Press, Inc. Boca Raton, FL. 1984. p. C-166; #3074.

Buckingham, J., Ed. Dictionary of Organic Compounds. 5th Ed. Chapman and Hall. New York. 1982. Vol. 5, p. 5479; #T-03193.

Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co. Rahway, NJ. 1983. pp. 158-159; #1114.

Bretherick, L., Ed. Hazards in the Chemical Laboratory. 3rd Ed. The Royal Society of Chemistry. London. 1981. pp. 197-198.

Sax, N.I. Dangerous Properties of Industrial Materials. 6th Ed. Van Nostrand Reinhold. New York. 1984. p. 391.

Weast, R.C. and M.J. Astle, Eds. CRC Handbook of Data on Organic Compounds. CRC Press, Inc. Boca Raton, FL. 1985. Vol. 1, p. 262; #B02373.

Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed. Van Nostrand Reinhold. New York. 1981. pp. 119-120.

U.S. Environmental Protection Agency, Office of Toxic Substances. Toxic Substances Control Act Chemical Substances Inventory, Initial Inventory. 6 Vols. U.S. Environmental Protection Agency. Washington, D.C. 1979. Listed.

Occupational Health Services, Inc. Hazardline. Occupational Health Services, Inc. New York. 1983. Listed.

Oak Ridge National Laboratory. Environmental Mutagen Information Center (EMIC), Bibliographic Data Base. Oak Ridge National Laboratory. Oak Ridge, TN. Not listed.

Oak Ridge National Laboratory. Environmental Teratogen Information Center (ETIC), Bibliographic Data Base. Oak Ridge National Laboratory. Oak Ridge, TN. Not listed. Aldrich Chemical Company.

Aldrich Catalog/Handbook of Fine Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI. 1984. p. 1073; #T6,370-3.

Occupational Safety and Health Administration. Tentative OSHA Listing of Confirmed and Suspected Carcinogens by Category. Occupational Safety and Health Administration. Washington, DC. 1979. Not listed.

[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to Industrial Chemicals Covered Under Major Federal Regulatory and Advisory Programs. Roytech Publications, Inc. Burlingame, CA. 1990. Section 3, p. 32.

[620] United States National Toxicology Program. Chemical Status Report. NTP Chemtrack System. Research Triangle Park, NC. October 3, 1990. Not listed.

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