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Adverse Effects
ACTIVITY:
Herbicide (anilide)
CAS NAME:
N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]-3-pyridinecarboxamide
Structure:
| Adverse
Effects:
Body
Weight Decrease
Bone
Cholesterol
Endocrine: Testicular
Endocrine: Thymus
Liver |
| Environmental
Effects:
Highly
persistent in soil and water |
Regulatory
Information
(only comprehensive for the US) |
| US
EPA Registered: |
No |
Registered
use in
(includes only a limited list of countries)
|
Australia,
Denmark, Finland, Germany, Japan, Netherlands, New Zealand,
Portugal, South Africa, Tanzania, UK, Vietnam |
| Japan's
Maximum Residue Levels (MRLs) |
Partial
List:
Apple,
Apricot, Barley, Beans (dry), Broad beans, Cherry, Grapefruit,
Lemon, Lime, Natsudaidai (whole), Nectarine, Orange, Peach,
Pear, Peas, Mume Plum, Quince, Rye, Soybeans (dry), Unshu orange,
Wheat |
Maximum
Residue Levels permitted
in food commodities
(includes
only a limited list of countries)
|
Australia:
Grape |
| Other
Information |
| Molecular
Formula: |
C19H11
F5 N2O2 |
| Entry
Year: |
1979 |
| Inventing
Company: |
May
& Baker |
| Manufacturers: |
Bayer,
Aventis, Rhone-Poulenc,
(May & Baker, Sandoz) |
| Other
Names: |
Ardent,
Cougar, Fenikan,
Grenadier, Ioniz, Javelin,
MB-38183, Panther,
Quartz, Spearhead, DFF,
Diflufenical, Kwarc |
| Manufacture
site: |
UK:
Aventis, Norwich, Norfolk
CHINA:
Shenyang Research Institute of Chemical Industry
CHINA:
Hebei Wanquan
Chemtech |
| Of
special interest: |
| PAN
Data |
| Material
Safety Data Sheets & Labels |
April
29, 2000 -
UK Department for Environment, Food
& Rural Affairs in the online report, "Design of
a Tax or Charge Scheme for Pesticides. " Annex C3: Overview
of Pesticide Industry |
September
1995 - Evaluation
on Diflufenican.
Department for Environment, Food
and Rural Affairs, Pesticides Safety Directorate, Mallard House,
Kings Pool, 3 Peasholme Green, York YO1 7PX, UK. Available at
http://www.pesticides.gov.uk/citizen/evaluations/evallist_alphabet.htm |
April
2002 - Beer
in the UK: 23 organofluorine pesticides approved for use on
malting barley.
Published by the British Beer and Pubs
Association and Brewing Research International. |
| See
NTIS reports below |
| October
2001 - Glossary
of Pesticide Chemicals. A listing
of pesticides subject to analysis of residues in foods and feeds
by the US Food and Drug Administration. |
Note
from FAN:
The following reports can be purchased
from NTIS (National Technical Information Service) via phone
at 703-605-6000. The cost for each report (generally on
fiche) is approximately $25.00. If you have a copy of any
of these reports please share them with us. - Thanks, EC.
|
Source:
EPA/OTS; Doc #88-920009606
INITIAL
SUBMISSION: LETTER FROM RHONE-POULENC INC TO USEPA REGARDING
A ONCOGENICITY AND TOXICITY STUDY OF DIFLUFENICAN IN MICE
WITH ATTACHMENTS AND COVER LETTER DATED
08-31-92
Corporate
Name: LIFE SCI RESEARCH
Keywords:
RHONE-POULENC INC
DIFLUFENICAN ; HEALTH EFFECTS ; CHRONIC TOXICITY ;
CARCINOGENICITY ; MAMMALS ; MICE ; ORAL ; DIET
Order
Number: NTIS/OTS0571263
|
Source:
EPA/OTS; Doc #88-920009402
INITIAL
SUBMISSION: TERATOLOGICAL STUDY OF N-(2,4-DIFLUOROPHENYL)-2-[3-(TRIFLUOROMETHYL)PHENOXY]-3-PYRIDINECARBOXAMIDE
IN RABBITS WITH COVER LETTER DATED
08/31/92
Keywords:
RHONE-POULENC INC ; [Diflufenican] ; HEALTH EFFECTS ; REPRODUCTION/FERTILITY
EFFECTS ; TERATOGENICITY ; MAMMALS ; RABBITS ; ORAL ; GAVAGE
; SUBCHRONIC TOXICITY
Order
Number: NTIS/OTS0555455
|
Source:
EPA/OTS; Doc #88-920009414
INITIAL
SUBMISSION: EFFECT OF N-(2,4-DIFLUOROPHENYL)-2-[3-(TRIFLUOROMETHYL)PHENOXY]-3-PYRIDINECARBOXAMIDE
IN PREGNANT RATS WITH COVER LETTER DATED
08/31/92
Corporate
Name: HUNTINGDON RESEARCH CTR
Keywords:
RHONE-POULENC INC [Diflufenican] ; HEALTH EFFECTS ; REPRODUCTION/FERTILITY
EFFECTS ; TERATOGENICITY ; MAMMALS ; RATS ; ORAL ; GAVAGE
; SUBCHRONIC TOXICITY
Order
Number: NTIS/OTS0555467
|
Source:
EPA/OTS; Doc #88-920009450
INITIAL
SUBMISSION: COMBINED ONCOGENICITY AND TOXICITY STUDY OF
N-(2,4-DIFLUOROPHENYL)-2-[3-(TRIFLUOROMETHYL)PHENOXY]-3-PYRIDINE-CARBOXIMIDE]
IN RATS WITH COVER LETTER DATED
08-31-92
Source:
EPA/OTS; Doc #88-920009450
Keywords:
RHONE-POULENC INC ; [Diflufenican] ; HEALTH EFFECTS ; CHRONIC
TOXICITY ; COMBINED CHRONIC TOXICITY/CARCINOGENICITY ; MAMMALS
; RATS ; ORAL ; DIET
Order
Number: NTIS/OTS0571106
|
Source:
EPA/OTS; Doc #88-920008945
INITIAL
SUBMISSION: EFFECT OF M&B 38544 ON REPRODUCTIVE FUNCTION
OF MULTIPLE GENERATIONS IN THE RAT WITH COVER LETTER DATED
08/31/92
Corporate
Name: HUNTINGDON RESEARCH CENTRE LTD
Keywords:
RHONE-POULENC INC ; M&G 38544 ; HEALTH EFFECTS ; REPRODUCTION/FERTILITY
EFFECTS ; COMBINED TERATOGENICITY/REPRODUCTIVE EFFECTS ;
MAMMALS ; RATS ; ORAL ; DIET ; CHRONIC TOXICITY ; COMBINED
CHRONIC TOXICITY/CARCINOGENICITY
Order
Number: NTIS/OTS0555262
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