Return to Epoxiconazole
Adverse Effects
ACTIVITY: Fungicide
(Triazole)
CAS Name: rel -1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole
Structure:
Adverse
Effects:
Body
Weight Decrease
Bone
Carcinogenic: LIVER
Endocrine: Adrenal
Endocrine: Ovary
Endocrine: Pituitary-Adrenal
axis
Endocrine: Suspected Disruptor
Liver |
Environmental
Effects:
1997.
European
Commission: Banned.
Low degradability, toxic to water-living
organisms and endocrine effects. |
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
Import
Tolerances Established |
US
EPA Chemical Code: |
123909 |
US Tolerances: |
40 CFR §180.619 |
FDA
LMS Code: |
B53 |
Note:
|
Norway:
Banned
- also, see box below |
US Tolerances: |
Import tolerances for banana
and coffee. |
Registered
use in
(includes only a limited list of countries)
|
Germany,
Hungary, Netherlands, New Zealand, Vietnam, South Africa, UK |
Other
Information |
Molecular
Formula: |
C17H13C1
F N3O |
Entry
Year: |
1995 |
Manufacturers: |
BASF |
Other
Names: |
BAS
480F, Opus® Fungicide, Opal® 7.5 EC Fungicide |
Of
special interest: |
PAN
Data |
August
2006. US
EPA Pesticide Fact Sheet. |
April
26, 2006. Chemicals
Evaluated for Carcinogenic Potential by the Office of Pesticide
Programs. From: Jess Rowland, Chief Science Information
Management Branch Health Effect Division (7509C) Office of Pesticide
Programs, USEPA. |
April
7, 2006. Too good to be
true: The pesticide scam. By Mike Abram. Farmers Weekly
(UK). |
Epoxiconazole
ranked number 14 for "Most Widely
used pesticides in the UK (by Area Treated)"
Rank
|
Formulation |
Method |
Area
treated (ha) |
Weight
applied (kg ai) |
14 |
Epoxiconazole |
Spray |
710,744 |
46,860 |
Ref:
April 29, 2000. UK Department for Environment, Food &
Rural Affairs in the online report, "Design of a Tax
or Charge Scheme for Pesticides. " Annex C3: Overview
of Pesticide Industry
http://www.fluorideaction.org/pesticides/pesticides.ranks.uk.2000.htm
|
June
14, 2001 - Implementation
of the Community Strategy for Endocrine Disruptors - a
range of substances suspected of interfering with the hormone
systems of humans and wildlife. Communication from the Commission
to the Council and the European Parliament. Commission of
the European Communities, Brussels COM (2001) 262 final. (More
information available at: http://europa.eu.int/comm/environment/docum/01262_en.htm
)
This
document presents a "priority list of substances for
further evaluation of their role
in
endocrine disruption. During 2000, a candidate list of 553
man-made substances
and 9 synthetic/natural hormones has been identified."
Organofluorine
pesticides in this list include: |
Substances
included on the Endocrine Disruptor Liist |
CAS
No. |
Substances
included on the Endocrine Disruptor Liist |
CAS
No. |
Bifenthrin |
82657-04-3
|
Flutriafol |
76674-21-0 |
Cyhalothrin
(@Karate) |
91465-08-6 |
Fluvalinate |
69409-94-5 |
Diflubenzuron |
35367-38-5 |
Prodiamine |
29091-21-2 |
Epoxiconazole |
135319-73-2 |
Stannane,
tributylfluoro [Tributyltin fluoride] |
1983-10-4 |
Fipronil |
- |
Thiazopyr |
- |
Fluazifop-butyl |
69806-50-4
|
Trifluralin |
- |
US
Federal Register |
Date
Published |
Docket
Identification Number |
Details |
September 13, 2006 |
EPA-HQ-2005-0071 |
BASF.
Pesticide
Tolerance. FINAL
RULE.
This regulation establishes tolerances for residues of epoxiconazole
in or on
-- Banana* at 0.5 ppm
-- Coffee* at 0.05 ppm
------------------------------------------------------------------------
*No U.S. Registration as of August 4, 2006 |
Feb 15,
2006 |
EPA-HQ-OPP-
2005-0071
PP
0E6128 |
BASF
- Pesticide
petition to establish tolerance. Pesticide Petition (PP
0E6128)
to establish
a tolerance for residues of the fungicide epoxiconazole, (2RS,3SR)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
in or on food commodity coffee bean at
0.05 ppm. Epoxiconazole residues are extracted from coffee
beans with methanol-water. After filtration and precipitation
of the interfering matrix components with calcium hydroxide,
epoxiconazole is extracted from the aqueous mixture with hexane
and chromatographed on silica gel. The samples are then analyzed
by GC/ECD. Average recovery from fortified control samples is
90 ± 8% (n=22). |
Sept
22, 2000 |
PF-961 |
BASF
- Petition
to Establish Tolerances for residues in or on bananas at 0.5
ppm and in or on banana pulp at 0.2 ppm. |
|