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Adverse Effects
Abstracts
ACTIVITY:
Herbicide (n-phenylphthalimide
or dicarboximide)
CAS Name:
2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
Structure:
Adverse
Effects:
Anemia
Blood
Body
Weight Decrease
Bone
Brain
Cholesterol
Cytotoxic (results equivocal)
Endocrine: Adrenal
Endocrine: Testicular
Endocrine: Thymus
Endocrine: Thyroid
Heart
Kidney
Liver
Lymph Node
Teratogen |
Environmental
Effects:
Phototoxic
Pesticide
Toxic
to aquatic invertebrates.
Highly
toxic to terrestrial plants |
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
Yes |
US
EPA PC Code: |
129034 |
California
Chemical Code |
5802
|
US
Tolerances: |
CFR
180.568 |
Registered
use in
(includes only a limited list of countries)
|
Argentina, China, Brazil, France, Hungary, Israel, Japan,
Paraguay, South Africa, USA, Zimbabwe.
Argentina,
soybean at 0.015 ppm; sunflower
at 0.02 ppm.
Brazil, soybean
at 0.05 ppm.
France, grape
at 0.05 ppm.
Paraguay, soybean
at 0.015 ppm.
South Africa, soybean
at 0.02 ppm; groundnut at 0.02
ppm.
Spain, soybean
at 0.05 ppm; peanut at 0.05 ppm.
Ref:
March 17, 2004, Federal
Register.
Japan
& US
- (see below) |
Japan
Maximum Residue Levels (MRLs) |
Apple
• Grape • Grapefruit • Japanese pear •
Lemon • Lime • NATSUDAIDAI (whole) • Orange
(including Navel) • Other Citrus fruits • Peanuts
(dry) • Pear • Soybeans (dry) • UNSHU orange |
US
Maximum Residue Levels permitted
in food commodities
|
Permitted
in or on 38 food commodities
Almond (hulls & nutmeat) • Cotton (gin byproducts
& undelinted seed) • Arracacha • Arrowroot •
Artichoke, (chinese & jerusalem) • Canna, edible •
Cassava • Chayote root • Chufa • Dasheen •
Garlic
(bulb) • Ginger • GrapeOnion
(dry bulb) • Leren • Peanuts • Peppermint
(tops) • Pistachio • Potato • Potato culls
• Potato granules flakes • Potato peel, wet •
Potato processed potato waste • Potato, specialty •
Shallot (bulb) • Soybean seed •
Spearmint (tops) • Sugarcane (cane) • Sweet potato
• Sweet Potato, Roots • Tanier • Turmeric
• Yam (bean & true) |
Other
Information |
Molecular
Formula: |
C19H15
F N2O4 |
Entry
Year: |
1989 |
Inventing
Company: |
Sumitomo |
Manufacturers: |
Sumitomo,
Valent |
Other
Names: |
BroadStar
Flumioxazine
Sumisoya
SureGuard
Valor 50 WD
S-53482
V-53482
59639-EUP-118 |
Manufacture
site: |
JAPAN:
SUMITOMO CHEMICAL COMPANY LTD, OITA WORKS, 2200 TSURUSAKI, OITA-CITY
OITA 870-01 |
Of
special interest: |
PAN
Data |
Material
Safety Data Sheets & Labels |
April
8, 2005 - Two new Valent
herbicides received okay from New York state: BroadStar
and SureGuard. |
December
2003 - Evaluation
of the new active Flumioxazin in the product Pledge 500 WG Herbicide.
Australian Pesticides and Veterinary Medicines Authority. ISSN1443-1335.
The applicant, Sumitomo Chemical Australia, is seeking registration
of the product for the knockdown and control of various grass
and broadleaved weeds when mixed with glyphosate or paraquat/diquat
herbicides prior to sowing wheat, barley, lupins, canola, cotton,
oats, faba beans, field peas, chick peas and lentils. |
January
2003 (revised) - Summary
of Toxicological Data. California
EPA, Department of Pesticides Regulation, Medical Toxicology
Branch. |
June
27, 2002. Review
report for the active substance flumioxazine. 7471/VI/98-Final.
European Commission. Directorate-General Health & Consumer
Protection. |
April
12, 2001 - US
EPA Pesticide Fact Sheet |
Profile
from Hazardous Substances Data Bank |
February
18, 2002 - European
Commission decision to extend provisional authorisation
granted for new active substances including flumioxazine |
March
7, 2001 - Phototoxic
Pesticides: US EPA Memo Requesting
Phototoxicity Study Protocol for Light-Dependent Peroxidizing
Herbicides |
Abstracts |
April
13, 2001 - Two
U.S. congressmen successfully campaign for flumioxazin use in
2001 growing season. - Press Release
from Saxby Chambliss, Georgia's 8th Congressional District.
|
April
17, 2001 - Georgia
Peanut Commission applauds EPA's approval. -
Press Release, Georgia Peanut Commission. |
August
2001 - IR-4:
New
Products/Transitional Solution List - This
list contains brief descriptions of numerous new pest control
materials that have been introduced over the last several years.
Additionally, it contains information on some "older"
crop protection chemicals that are believed to have room for
new uses. This List includes: Flumioxazin
|
October
2001 - Glossary
of Pesticide Chemicals - A listing
of pesticides subject to analysis of residues in foods and feeds
by the US Food and Drug Administration. |
US
Federal Register
••
Note: Due to length, the following is a partial list. Click
here to see full list of FR entries.
|
Published
Date |
Docket
Identification Number |
Details |
September 28, 2007 |
EPA-HQ-OPP-2007-0871 |
Valent U.S.A. Corporation. Proposed pesticide tolerance. Pesticide Petition (PP 7F7243) to establish a tolerance for residues of the herbicide flumioxazin in or on the food commodities
-- corn, field grain at 0.02 ppm;
--
corn, field forage at 0.02 ppm
-- corn, field stover at 0.02 ppm.
Practical analytical methods for detecting and measuring levels of flumioxazin have been developed and validated in or on all appropriate agricultural commodities and respective processing fractions. The level of quantitation (LOQ) of flumioxazin in the methods is 0.02 ppm which will allow monitoring of food with residues at the levels proposed for the tolerances. |
September 28, 2007 |
EPA-HQ-OPP-2006-0781 |
Valent U.S.A. Corporation. Proposed pesticide tolerance. Pesticide Petition (6F7092) proposes to establish a tolerance for residues of the herbicide in or on the food commodities
-- alfalfa, forage at 1.0 ppm and
--
alfalfa, hay at 2.0 ppm. |
June 27, 2007 |
EPA-HQ-OPP-2007-0308 |
IR-4.
Pesticide
Petition. PP 6E7151. Proposal to establish a tolerance
for residues of the herbicide flumioxazin in or on food commodities:
asparagus |
0.02 ppm |
aronia berry |
0.02 ppm |
dry beans |
0.10 ppm |
buffalo currant |
0.02 ppm |
Bushberry, subgroup
13B
This subgroup includes
5 commodities.
blueberry • currant • elderberry •
gooseberry • huckleberry
|
0.02 ppm |
Chilean guava |
0.02 ppm |
European barberry |
0.02 ppm |
highbush cranberry |
0.02 ppm |
honeysuckle |
0.02 ppm |
jostaberry |
0.02 ppm |
Juneberry |
0.02 ppm |
lingonberry |
0.02 ppm |
melon, subgroup
9A
This subgroup includes
6 commodities.
cantaloupe • citron melon • melon •
melon, citron • muskmelon • watermelon
|
0.02 ppm |
Native currant |
0.02 ppm |
nut, tree, crop
group 14
This group includes
16 commodities.
almond • almond, hulls • beechnut •
butternut • cashew • chestnut •
chinquapin • filbert • nut, brazil •
nut, hickory • nut, macadamia • nutmeat,
processed, except peanut • nuts • pecan
• pistachio • walnut
|
0.02 ppm |
okra |
0.02 ppm |
salal |
0.02 ppm |
sea buckthorn |
0.02 ppm |
vegetable, fruiting, crop
group 8
This group includes
17 commodities.
chili, postharvest • eggplant • groundcherry
• pepino • pepper • pepper, bell
• pepper, nonbell • pepper, nonbell, sweet
• tomatillo • tomato • tomato, concentrated
products • tomato, dried pomace • tomato,
paste • tomato, puree • tomato, wet pomace
• vegetable, fruiting • vegetable, fruiting,
group
|
0.02 ppm |
Practical analytical methods for detecting
and measuring levels of flumioxazin have been developed and
validated in/on all appropriate agricultural commodities and
respective processing fractions. The LOQ of flumioxazin in
the methods is 0.02 ppm which will allow monitoring of food
with residues at the levels proposed for the tolerances. |
June 27, 2007 |
EPA-HQ-OPP-2007-0308 |
IR-4.
Pesticide
Petition. PP 6E7151. Porposal to amend the tolerances in
40 CFR 180.568 for residues of the herbicide flumioxazin in
or on the food commodity almond, nutmeats be deleted upon establishment
of the crop group tolerance for nut, tree, Crop Group 14. |
May 3, 2006 |
EPA-HQ-OPP-2004-0398 |
Valent U.S.A.
Pesticide
tolerance. FINAL
RULE. -- Strawberry
at 0.07 ppm
-- Fruit, pome, group
11 at 0.02 ppm
This group includes 10 commodities.
apple • apple, dried pomace • apple, juice •
apple, wet pomace • crabapple • fruit, pome
• loquat • mayhaw • pear • pear,
oriental • quince
-- Fruit, stone, group
12 at 0.02 ppm
This group includes 14 commodities.
apricot • cherry, sweet • cherry, tart •
fruit, stone • fruit, stone, except plum, prune, dried
• nectarine • peach • plum • plum,
chickasaw • plum, damson • plum, japanese •
plum, prune • plum, prune, dried • plum, prune,
fresh
|
August
17, 2005 |
OPP-2005-0222 |
Requests
to Voluntarily Cancel Certain Pesticide Registrations.
Registration no. |
Product
Name |
Chemical
Name |
Registrants
Requesting Voluntary Cancellation |
059639
SD-02-0001 |
Valor
WDG Herbicide |
Flumioxazin |
Valent
U.S.A. Corp., PO Box
8025, Walnut Cre, CA 94596. |
059639
SD-03-0003 |
Gangster
V Herbicide |
Flumioxazin |
Valent
U.S.A. Corp., PO Box
8025, Walnut Cre, CA 94596. |
|
April
8, 2005 |
OPP-2005-0089 |
IR-4.
Notice of Filing a Pesticide Petition to Establish a Tolerance
in
or on STRAWBERRY at 0.10 ppm.
PP
(Pesticide Petition) 4E6845.
The
toxicological profile for flumioxazin which supports this
petition for tolerances was published in the Federal
Register on March 31, 2004. |
Nov
10, 2004 |
OPP-2004-0232 |
Three
Pesticide Emergency Exemptions.
• Louisiana
--- Crisis:
On May 7, 2004, for the use of flumioxazin
on sweet potatoes to control
annual broadleaf weeds. This program ended on July 15, 2004.
Contact: (Libby Pemberton)
--- Specific: EPA authorized the use of flumioxazin
on sweet potatoes to control
annual broadleaf weeds; May 13, 2004 to July 31, 2004.
Contact: (Libby Pemberton)
• Mississippi - EPA authorized
the use of flumioxazin on sweet
potatoes to control annual broadleaf weeds; May 13,
2004 to July 31, 2004. Contact: (Libby Pemberton) |
••
Note: Due to length, the above is a partial list. Click
here to see full list of FR entries.
|
|