Lambda-cyhalothrin
CAS No. 91465-08-6

US Federal Register
 
 

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ACTIVITY: Insecticide (pyrethroid)

Note: The unresolved isomeric mixture of this substance has the ISO common name cyhalothrin.

CAS Name: rel-(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethylcyclopropanecarboxylate

Structure:

 

US Federal Register

Date Published Docket Identification Number Details
October 11, 2006 EPA-HQ-OPP-2005-0545 Pesticide petition: 6E7077.
Proposed tolerances for Lambda-cyhalothrin and its
epimer in or on food commodity
-- pistachio at 0.05 ppm.
August 25, 2006 EPA-HQ-OPP-2006-0659 Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations
• Wyoming. Specific: EPA authorized the use of lambda-cyhalothrin on barley to
control Russian wheat aphids, cereal leaf beetles, and cutworms; April
14, 2006 to July 31, 2006.
June 7, 2006 EPA-HQ-OPP- 2006-0387

Pesticide Emergency Exemptions; Agency Decisions and State and
Federal Agency Crisis Declarations
.
• Colorado: EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids, cereal leaf beetle, and cutworms; April 7, 2006 to July 15, 2006.
• Minnesota: Specific: EPA authorized the use of lambda-cyhalothrin on wild rice to control riceworms; August 1, 2006 to September 10, 2006.
• Montana: Specific: EPA authorized the use of lambda-cyhalothrin on barley to control the cereal leaf beetle, Russian wheat aphid, and cutworms; March 15, 2006 to July 30, 2006.

April 14, 2006 EPA-HQ-OPP-2005-0545 Syngenta. Pesticide petition: 5F6994.
for the combined residues of the insecticide
lambda-cyhalothrin and its epimer, in or on food commodity crop groupings:
-- Cucurbit vegetables (Crop Group 9) at 0.05 ppm

This group includes 19 commodities.
balsam apple • balsam pear • cantaloupe • chayote, fruit • cucumber • cucumber, chinese • cucurbits • gherkin, west indian • gourd, edible • melon • melon, citron • muskmelon • pumpkin • squash • squash, summer • squash, winter • vegetable, cucurbit, group • watermelon • waxgourd, chinese

-- grass, forage, fodder, hay (Crop Group 17) at 9.0 ppm

This group includes 360 commodities. See http://www.fluorideaction.org/pesticides/us.epa.commodity.groups.html

-- tuberous and corm vegetables (Crop Subgroup 1-C) at 0.01 ppm

This subgroup includes 22 commodities.
arracacha • arrowroot • artichoke, chinese • artichoke, jerusalem • canna, edible • cassava • chayote root • chufa • dasheen • ginger • leren • potato • potato culls • potato granules flakes • potato peel, wet • potato processed potato waste • potato, specialty • sweet potato • tanier • turmeric • yam bean • yam, true

-- barley, buckwheat, oat, rye, grain at 0.05 ppm
-- barley, bran at 0.2 ppm
-- oat, rye, forage at 2.0 ppm
-- barley, oat, hay at 2.0 ppm
-- barley, oat, rye, straw at 2.0 ppm
-- wild rice, grain at 1.0 ppm.

Dec 21, 2005 EPA-HQ-OPP-2005-0292

Extension of Tolerances for Emergency Exemptions. FINAL RULE.

Lambda-cyhalothrin. EPA has authorized under FIFRA section 18 the use of lambda-cyhalothrin on barley for control of the Russian wheat aphid and cutworms in Idaho, Colrado, Wyoming and Montana. This regulation extends time-limited tolerances for combined residues of the pyrethroid lambda-cyhalothrin in or on barley grain at 0.05 ppm, barley bran at 0.2 ppm, and barley hay and straw at 2.0 ppm for an additional 3-year period. These tolerances will expire and are revoked on December 31, 2008. Time-limited tolerances were originally published in the Federal Register of October 29, 1997.

Lambda-cyhalothrin. EPA has authorized under FIFRA section 18 the use of lambda-cyhalothrin on alfalfa/clover/grass mixed stands for control of potato leafhoppers in New York. This regulation extends time-limited tolerances for combined residues of the pyrethroid lambda-cyhalothrin in or on Clover, forage at 5.0 ppm; Clover, hay at 6.0 ppm; Grass, forage at 5.0 ppm; and Grass, hay at 6.0 ppm for an additional 3-year period. These tolerances will expire and are revoked on December 31, 2008. Time-limited tolerances were originally published in the Federal Registers of January 3, 2003 and September 3, 2003.

Lambda-cyhalothrin. EPA has authorized under FIFRA section 18 the use of lambda-cyhalothrin on wild rice for control of rice worms in Minnesota. This regulation extends a time-limited tolerance for combined residues of the pyrethroid lambda-cyhalothrin in or on rice, wild at 1.0 ppm for an additional 3-year period. These tolerances will expire and are revoked on December 31, 2008. The time-limited tolerance was originally published in the Federal Register of January 3, 2003.

Nov 16, 2005 OPP-2005-0277 Pesticide Emergency Exemptions.
• Minnesota. EPA authorized the use of lambda-cyhalothrin on wild rice to control rice worms; June 30, 2005 to September 10, 2005.
August 31, 2005 OPP-2005-0223

Pesticide Emergency Exemptions:

• Minnesota. EPA authorized the use of lambda-cyhalothrin on wild rice to control rice worms; June 30, 2005 to September 10, 2005. Contact: (Andrew Ertman).
• New York. EPA authorized the use of lambda-cyhalothrin on alfalfa/clover/grass mixed stands to control potato leafhopper; June 10, 2005 to August 31, 2005. Contact: (Andrew Ertman).

August 3, 2005 OPP-2005-0201

Cancellation of Pesticides for Non-payment of Year 2005 Registration Maintenance Fees.

Section 24(c) Registrations canceled for non-payment of the 2005
maintenance fee are shown in the following Table 1:

Table 1.--Section 24(c) Registrations Canceled for Non-Payment of Maintenance Fee

SLN no. Product Name
000100 WA-99-0006 Warrior T Insecticide
March 10, 2005 OPP-2005-0057 Requests to Voluntarily Cancel Certain Pesticide Registrations.
Unless a request is withdrawn by September 6, 2005, orders will be issued canceling these registrations. The Agency will consider withdrawal requests postmarked no later than September 6, 2005.
Chemical Name Registration No. Product Name Company Name and Address
lambda-Cyhalothrin 000100-01155 Impasse Premi Pel Syngenta Crop Protection, Inc., Greensbo, NC
274198300
000100 WA-99-0006 Warrior T lambda-Cyhalothrin
Insecticide
Nov 10, 2004 OPP-2004-0232

Pesticide Emergency Exemption.
Wyoming - EPA authorized the use of lambda-cyhalothrin on barley to control the Russian wheat aphid; April 23, 2004 to July 31, 2004. Contact: (Andrew Ertman)

Oct 27, 2004 OPP-2004-0338 Cancellation of Pesticides for Non-payment of Year 2004 Registration Maintenance Fees.
Table 1.--Section 24(c) Registrations Canceled for Non-Payment of
Maintenance Fee
Name of Pesticide Product Name Registrant SLN No.
Cyhalothrin, lambda Karate Insecticide - Syngenta Crop Protection, Inc. 000100 TN-99-0005
Cyhalothrin, lambda Warrior Insecticide Syngenta Crop Protection, Inc. 000100 MT-95-0006.
Cyhalothrin, lambda Warrior Insecticide Syngenta Crop Protection, Inc. 000100 UT-96-0002
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 AL-99-0004
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 ND-99-0010
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 GA-98-0005
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 MN-99-0015
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 MO-99-0004
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 SD-99-0005
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 OR-99-0029
Cyhalothrin, lambda Warrior T Insecticide Syngenta Crop Protection, Inc. 000100 WA-99-0024

Table 2.--Section 3 Registrations Canceled for Non-Payment of Maintenance Fee
Name of Pesticide Product Name Registrant Registration No.
Cyhalothrin, lambda Commodore EC Insecticide Syngenta Crop Protection, Inc. 000100-01011
Cyhalothrin, lambda  Commodore Insecticide In Ready Mix Water Soluble Packet
Syngenta Crop Protection, Inc.  000100-01085
Cyhalothrin, lambda Commodore WP Insecticide Syngenta Crop Protection, Inc. 000100-01044
Cyhalothrin, lambda
Commodore WP Insecticide In
Water-Soluble Packets
Syngenta Crop Protection, Inc. 000100-01058
Cyhalothrin, lambda Lambda-Cyhalothrin CS
Insecticide 
Syngenta Crop Protection, Inc.   000100-01096
Cyhalothrin, lambda Scimitar WP Insecticide Syngenta Crop Protection, Inc.    000100-01045
Cyhalothrin, lambda  Scimitar WP Greenhouse Insecticide In Water Soluble Packets  Syngenta Crop Protection, Inc.    000100-01076
Cyhalothrin, lambda   Scimitar G & N Insecticide In
Water Soluble Packets 
Syngenta Crop Protection, Inc.   000100-01100 
Cyhalothrin, lambda  Scimitar WP Greenhouse
Insecticide
Syngenta Crop Protection, Inc.    000100-01077 
Cyhalothrin, lambda  Scimitar CS Greenhouse Insecticide   Syngenta Crop Protection, Inc.    000100-01081 
Cyhalothrin, lambda  Scimitar WP Golf Course Turf
Insecticide
Syngenta Crop Protection, Inc.    000100-01089 
Cyhalothrin, lambda  Scimitar WP Turf and
Ornamental Insecticide  
Syngenta Crop Protection, Inc.    000100-01090 
August 18, 2004 OPP-2004-0054 Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations.
The following pesticide products are produced by:
Syngenta Crop Protection, Inc.
,
Attn: Regulatory Affairs, PO Box 18300, Greensboro, NC 27419-8300.
EPA Company No: 000100  
EPA Registration No. Product Name
000100-01011   Commodore EC Insecticide
000100-01044  Commodore WP Insecticide
000100-01045  Scimitar WP Insecticide
000100-01058 Commodore WP Insecticide In Water-Soluble Packets
000100-01076
Scimitar WP Greenhouse Insecticide In Water Soluble Pac
000100-01077 Scimitar WP Greenhouse Insecticide
000100-01081 Scimitar CS Greenhouse Insecticide
000100-01085 Commodore Insecticide In Ready Mix Water Soluble Packet
000100-01089 Scimitar WP Golf Course Turf Insecticide
000100-01090 Scimitar WP Turf and Ornamental Insecticide
000100-01096 Lambda-Cyhalothrin CS Insecticide
000100-01100 Scimitar G Insecticide In Water Soluble Packets
000100 AL-99-0004 Warrior T Insecticide
000100 CO-03-0001 Warrior Insecticide with Zeon Technology
000100 MN-95-0005  Fusilade DX Herbicide
000100 MN-99-0015 Warrior T Insecticide
000100 MT-95-0006  Warrior Insecticide
000100 ND-99-0010   Warrior T Insecticide
000100 WA-99-0024  Warrior T Insecticide
May 5, 2004 OPP-2004-0116 Pesticide Emergency Exemptions.
Colorado - EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphid and cereal leaf beetle; April 15, 2004 to July 15, 2004.
Idaho - EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids, cereal leaf beetles, armyworms, and cutworms; May 1, 2004 to July 30, 2004.
Minnesota - EPA authorized the use of lambda-cyhalothrin on wild rice to control rice worms; August 1, 2004 to September 10, 2004.
Montana - EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids, cereal leaf beetles and cutworms; April 1, 2004 to July 30, 2004.
New York - EPA authorized the use of lambda-cyhalothrin on alfalfa/clover/grass mixed stand to control potato leafhopper; June 1, 2004 to August 31, 2004.
April 8, 2004 OPP-2004-0025

Pytech. Lambda-Cyhalothrin and Gamma-Cyhalothrin. Tolerances for Residues. FINAL RULE. EPA is amending 40 CFR part 180 by promulgating a new tolerance expression for the isomer form of gamma-cyhalothrin. Gamma-cyhalothrin is the isolated active isomer of lambda-cyhalothrin under 40 CFR 180.438. Pytech Chemicals GmbH, 9330 Zionsville Rd., Indianapolis, IN 46268, requested this change in tolerance expression in support of the registration of a pesticide formulation enriched with the gamma isomer of lambda-cyhalothrin.

EPA's previous risk assessment on lambda-cyhalothrin (September 27, 2002, Federal Register) is sufficient to cover gamma-cyhalothrin. Accordingly, a new aggregate risk assessment for gamma-cyhalothrin is not needed.

It is noted that in the developmental toxicity study in the rat that the resolved gamma isomer is over an order of magnitude more toxic than in cyhalothrin.

Excerpts from Table 1.-- Subchronic, Chronic, and Other Toxicity
Study Type Results

13-Week Dietary - Rat
- Gamma cyhalothrin

(Guideline No. 870.3100)

NOAEL: male/female =3.4/4.2 mg/kg/day
LOAEL: male/female = 6.6/8.8 mg/kg/day
(mortality in males, neuromuscular effects in both sexes, dermatitis, and gross and microscopic skin lesions in females).

3-Generation Reproduction - Rat
Cyhalothrin
Lambda cyhalothrin
Gamma cyhalothrin

(Guideline No. 870.3800)

Parental NOAEL: 1.5 mg/kg/day
Parental LOAEL: 5.0 mg/kg/day
(decreased parental body weight and body weight gain during premating and gestation periods).

Reproductive NOAEL: 5.0 mg/kg/day
Reproductive LOAEL: Not established.
Offspring NOAEL: 1.5 mg/kg/day
Offspring LOAEL: 1.5 mg/kg/day (reduced pup weight and weight gain during lactation).

21-Day Inhalation Toxicity - Rat
Lambda cyhalothrin
Cyhalothrin
Gamma cyhalothrin

(Guideline No. 870.3465)

NOAEL: 0.08 mg/kg/day
LOAEL: 0.90 mg/kg/day (clinical signs of neurotoxicity, decreased body weight gains, increased incidence of punctate foci in cornea,
slight reductions in cholesterol in females, slight changes in selected urinalysis parameters).

Gamma cyhalothrin

(Guideline No. 870.3200)

Maternal NOAEL: 0.5 mg/kg/day
Maternal LOAEL: 2.0 mg/kg/day
(clinical signs, reduced body weight and body weight gain and food consumption).
Developmental NOAEL: 2.0 mg/kg/day
Developmental LOAEL: Not established

Gamma cyhalothrin

(Guideline No. 870.3200)


NOAEL: male/female = 4.2/4.5 mg/kg/day
LOAEL: male/female = 8.8/10.2 mg/kg/ day.
(decreased body weight, body weight gain, food consumption, clinical and biochemical effects)

Chronic Toxicity - Dog
Lambda cyhalothrin
Cyhalothrin
Gamma cyhalothrin

(Guideline No. None)

NOAEL: 0.1 mg/kg/day
LOAEL: 0.5 mg/kg/day (clinical signs of neurotoxicity).
Note: For one or two days of dosing, the NOEL is 0.5 mg/kg.

Excerpts from Table 2.-- Summary of Toxicological Dose and Endpoints for Gamma-Cyhalothrin for Use in Human Risk Assessment
Note: No study in this Table references Gamma-cyhalothrin
Exposure Scenario Study and Toxicological Effects
Acute dietary general population including
(infants and children)
Chronic oral study in the dog (lambda-cyhalothrin) Clinical signs of neurotoxicity (ataxia) observed from day 2, 3 to 7 hours post dosing.
Chronic dietary (all populations) Chronic oral study in the dog (lambda-cyhalothrin) Gait abnormalities observed in two dogs.
Short-term dermal (1 to 30 days)
Long-term dermal (< 6 months)
21-Day dermal toxicity study in the rat (lambda- cyhalothrin)
Clinical signs of neurotoxicity
(observed from day 2) and decreased body weight and body weight gain.

Tolerances are established for the combined residues of the pyrethroid [gamma-cyhalothrin (the isolated active isomer of lambda-cyhalothrin) and its epimer (R)-'-cyano-3-phenoxybenzyl (Z)-(1R,3R)-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate in/on the following commodities:

Commodity PPM Commodity PPM
Alfalfa, forage 5 Pea and bean, dried shelled,(except soybean), subgroup
See Ref. 5
0.10
Alfalfa, hay 6 Pea and bean, succulent shelled, subgroup
See Ref. 6
0.01
Almond, hulls 1.5 Peanut 0.05
Apple pomace, wet 2.50 Peanut, hay 3.0
Aspirated grain fractions 2.0 Poultry, fat 0.03
Avocados (imported) 0.20 Poultry, meat 0.01
Brassica, head and stem, subgroup
See Ref. 1
0.4 Poultry, meat byproducts 0.01
Canola, seed 0.15 Rice, grain 1.0
Cattle, fat 3 Rice, hulls 5.0
Cattle, meat 0.2 Rice, straw 1.8
Cattle, meat byproducts 0.2 Sheep, fat 3.0
Corn, grain (field and pop) 0.05 Sheep, meat 0.2
Corn, fodder 1.0 Sheep, meat byproducts 0.2
Corn, forage 6.0 Sorghum, grain. 0.20
Corn, grain flour 0.15 Sorghum, grain, forage 0.30
Corn, sweet, kernel plus cob with husks removed 0.05 Sorghum, grain, stover 0.50
Cottonseed 0.05 Soybean 0.01
Dry bulb onion 0.1 Sugarcane 0.05
Egg 0.01 Sunflower, forage 0.20
Fruit, pome, group
See Ref. 2
0.30 Sunflower, seed hulls 0.50
Fruit, stone, group
See Ref. 3
0.50 Sunflower, oil 0.30
Garlic 0.10 Sunflowers, seed 0.20
Goat, fat 3.0 Tomato 0.10
Goat, meat 0.2 Tomato, pomace (dry or wet) 6.0
Goat, meat byproducts 0.2 Vegetables, fruiting, group (except cucurbits)
See Ref. 7
0.20
Hog, fat 3.0 Vegetables, legume, edible podded, subgroup
See Ref. 8
0.20
Horse, meat 0.2 Wheat, grain 0.05
Horse, meat byproducts 0.2 Wheat, forage 2.0
Lettuce, head 2.0 Wheat, hay 2.0
Lettuce, leaf 2.0 Wheat, straw 2.0
Milk fat (reflecting 0.20 ppm in whole milk 5.0 Wheat, bran 2.0
Nut, tree, group
See Ref. 4
0.05 Hop, dried cone. 10

Ref. 1 broccoli; broccoli, cavalo; broccoli, chinese; brussels sprout; cabbage; cabbage, chinese mustard; cabbage, chinese napa; cauliflower; cavalo broccolo; kohlrabi
Ref. 2 apple; apple, dried pomace; apple, juice; apple, wet pomace; crabapple; fruit, pome; loquat; mayhaw; pear; pear, oriental; quince
Ref. 3 apricot; cherry, sweet; cherry, tart; fruit, stone; fruit, stone, except plum, prune, dried; nectarine; peach; plum; plum, chickasaw; plum, damson; plum, japanese; plum, prune; plum, prune, dried; plum, prune, fresh
Ref. 4 almond; almond, hulls; beechnut; butternut; cashew; chestnut; chinquapin; filbert; nut, brazil; nut, hickory; nut, macadamia; nutmeat, processed, except peanut; nuts; pecan; pistachio; walnut
Ref. 5 bean, adzuki; bean, broad dry; bean, dry; bean, kidney; bean, lablab; bean, lima dry; bean, moth; bean, mung; bean, navybean, pink; bean, pinto; bean, rice; bean, tepary; bean, urd; catjang; chickpea; cowpea; guar; lentil; lupin, grain; lupin, sweet; pea, blackeyed; pea, crowder; pea, field; pea, field seed; pea, pigeon; pea, southern
Ref. 6 bean, broad succulent; bean, lima succulent; cowpea; cowpea seed; pea, blackeyed; pea, english; pea, garden; pea, green; pea, pigeon; pea, southern
Ref. 7 chili, postharvest; eggplant; groundcherry; pepino; pepper; pepper, bell;
pepper, nonbell; pepper, nonbell, sweet; tomatillo; tomato; tomato, concentrated products; tomato, dried pomace; tomato, paste; tomato, puree;
tomato, wet pomace; vegetable, fruiting; vegetable, fruiting, group
Ref. 8 bean, moth; bean, runner; bean, snap; bean, wax; bean, yardlong; jackbean;
longbean, chinese; pea, dwarf; pea, edible podded; pea, pigeon; pea, snow; pea, sugar snap; soybean immature seed; swordbean
March 3, 2004 ORD-2003-
0011

Announcement: Longitudinal Study of Young Children's Exposures in their Homes to Selected Pesticides, Phthalates, Brominated Flame Retardants, and Perfluorinated Chemicals (A Children's Environmental Exposure Research Study--CHEERS).

Abstract: The U.S. EPA's Office of Research and Development's National Exposure Research Laboratory proposes to conduct a two-year longitudinal field measurement study of young children's (aged 0 to 3 years) potential exposures to current-use pesticides and selected phthalates, polybrominated diphenyl ethers, and perfluorinated compounds that may be found in residential environments. The study will be conducted in Duval County, Jacksonville, Florida over a two-year period from 2004 to 2006. Sixty young children will be recruited into this study in two cohorts: (1) infants recruited into the study soon after birth, and, (2) children recruited into the study at approximately 12 months of age.

Part A: Supporting Statement - EPA ICR Number: 2126.01 - 61 pages
From Table 2:
• Of 16 pesticides included in this study, 4 are fluorinated:
Bifenthrin, Fipronil, Lamda-cyhalothrin, and Cyfluthrin I, II, III, IV, total
• Perfluorinated chemicals:
Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate (PFOS)

From Table 3: List of chemicals to be analyzed in biological media:
• one is fluorinated: 4-fluoro-3-phenoxybenzoic acid
• Perfluorooctanoic acid/Perfluorooctane sulfonate

•• See Update on CHEERS study

Note: On Feb 25, 2004: Pytech. Pesticide tolerance petition; proposal to amend 40
CFR part 180 by adding gamma-cyhalothrin to the tolerance expression of lambda-cyhalothrin. Gamma-cyhalothrin is the isolated active isomer of lambda-cyhalothrin.

Nov 26, 2003 OPP-2003-0358 6 Pesticide Emergency Exemptions.
-- Colorado Department of Agriculture. Crisis. On February 18, 2003, for the use of lambda-cyhalothrin on alfalfa/grass mixed stands, pasture land and range land, and grass grown for seed to control army cutworms. This program ended on June 15, 2003.
-- Idaho Department of Agriculture. Specific. EPA authorized the use of lambda-cyhalothrin on barley to control the Russian wheat aphid, and cereal leaf beetle; April 4, 2003 to July 30, 2003.
-- Montana Department of Agriculture. Crisis. On May 21, 2003, for the use of lambda-cyhalothrin on barley to control cutworms and cereal leaf beetles. This program ended on July 30, 2003.
-- Montana Department of Agriculture. EPA authorized the use of lambda-cyhalothrin on barley to control the Russian wheat aphid, cereal leaf beetles, and cutworms; June 8, 2003 to July 30, 2003.
-- New York Department of Environmental Conservation. EPA authorized the use of lambda-cyhalothrin on alfalfa/clover/ grass mixed stands to control the potato leafhopper; June 1, 2003 to August 31, 2003.
-- Wyoming Department of Agriculture. Specific. EPA authorized the use of lambda-cyhalothrin on barley to control the Russian wheat aphid; April 10, 2003 to July 31, 2003.
Sept 30, 2003 NA PFOS / PFOAS. September 30, 2003. Federal Register.
Candidate Chemicals for Possible Inclusion in Future Releases of the National Report on Human Exposure to Environmental Chemicals.
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
-- Two fluorinated pesticides were included:
Group 2
Lambda cyhalothrin and Trifluralin
Sept 3, 2003 OPP-2003-0267

Pesticide Tolerances for Emergency Exemptions in New York State. Final Rule. To establish tolerances for combined residues of the insecticide lambda-cyhalothrin and its epimer, in or on

clover, forage 5.0 ppm
clover, hay 6.0 ppm

-- These tolerances will expire and are revoked on December 31, 2005.
-- The state of New York requested the use. Experts estimate a 35% yield loss if these mixed stands are not protected. EPA has authorized under FIFRA section 18 the use of lambda-cyhalothrin on alfalfa/clover/grass mixed stands for control of alfalfa weevil, armyworms and potato leafhoppers in New York.
-- Chronic oral study in the dog (lambda-cyhalothrin) day. LOAEL = 3.5 mg/ kg/day based on clinical signs of neurotoxicity (ataxia) observed from day 2, 3 to 7 hours post- dosing.
-- Chronic oral study in the dog (lambda-cyhalothrin). LOAEL = 0.5 based on gait abnormalities observed in 2 dogs.
-- 21-Day dermal toxicity study in the rat (lambda-cyhalothrin). LOAEL = 50 mg/kg/day (Residential) based on clinical signs of neurotoxicity (observed from day 2) and decreased body weight and body weight gain
-- 21-Day Inhalation Study in Rats (lambda-cyhalothrin). LOAEL = 3.3 [mu]g/L (0.90 mg/kg/day) based on clinical signs of neurotoxicity, decreased body weight gains, increased incidence of punctuate foci in the cornea, slight reductions in cholesterol in females and slight changes in selected urinalysis parameters.
-- The requirements for oncogenicity studies in the rat and the mouse with lambda-cyhalothrin have been satisfied by a combined chronic/ oncogenicity study in rats and an oncogenicity study in mice, both conducted with cyhalothrin. [FAN NOTE: NOT Lambda-cyhalothrin...]
-- In a developmental toxicity study in rats, the maternal NOAEL was 10 mg/kg/day and the LOAEL was 15 mg/kg/day based on uncoordiniated limbs, reduced body weight gain and food consumption. The developmental NOAEL was 15 mg/kg/day (HDT) and the developmental LOAEL was > 15 mg/kg/day.
-- Reproductive toxicity study. In a 3-generation reproduction study in rats, the parental/offspring NOAEL was 1.5 mg/kg/day and the LOAEL was 5.0 mg/kg/day based on decreased parental body weight and body weight gain during premating and gestation periods and reduced pup weight and weight gain during lactation. The reproductive NOAEL was 5.0 mg/kg/day (HDT)

May 7, 2003 OPP-2003-0149

Emergency Exemptions for pesticide use.

-- Colorado Department of Agriculture. EPA authorized the use of lambda-cyhalothrin on barley to control the Russian wheat aphid and the cereal leaf beetle; April 15, 2003 to July 15, 2003.
--
Minnesota Department of Agriculture. EPA authorized the use of lambda-cyhalothrin on wild rice to control rice worms; August 1, 2003 to September 10, 2003.

Feb 24, 2003 OPP-2003-0033

Pesticide Emergency Exemption:

California. EPA authorized the use of a baited trap containing lambda- cyhalothrin (toxicant), ammonium bicarbonate (food lure), and spiroketalamine (pheromone) on olive trees to control the olive fruit fly; November 14, 2002 to August 31, 2003.

Jan 16, 2003 OPP-2002-0336

Extension of Tolerances for Emergency Exemptions. EPA has authorized under FIFRA section 18 the use of lambda-cyhalothrin on barley for control of the Russian wheat aphid and cutworms in Idaho, Colrado, Wyoming, and Montana. This regulation extends a time-limited tolerance for combined residues of the pyrethroid lambda-cyhalothrin, 1:1 mixture of (S)-[alpha]-cyano-3- phenoxybenzyl-(Z)-(1R,3R)-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2- dimethylcyclopropanecarboxylate and (R)-[alpha]-cyano-3-phenoxybenzyl- (Z)-(1S,3S)-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2- dimethylcyclopropanecarboxylate and its epimer expressed as epimer of lambda-cyhalothrin, a 1:1 mixture of (S)-[alpha]-cyano-3-phenoxybenzyl- (Z)-(1S,3S)-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2- dimethylcyclopropanecarboxylate and (R)-[alpha]-cyano-3-phenoxybenzyl- (Z)-(1R,3R)-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2- dimethylcyclopropanecarboxylate in or on barley grain at 0.05 ppm, barley bran at 0.2 ppm, and barley hay and straw at 2.0 ppm for an additional 3-year period. These tolerances will expire and are revoked on December 31, 2005. Time-limited tolerances were originally published in the Federal Register of October 29, 1997 (62 FR 56095) (FRL-5745-5)

Jan 3, 2003 OPP-2002-0335

Pesticide tolerances for emergency exemption use in MN and NY. FINAL RULE.
Chronic oral study in the dog (lambda- cyhalothrin) LOAEL = 3.5 mg/kg/day based on clinical signs of neurotoxicity (ataxia) observed from day 2, three to seven hours post-dosing.
Chronic oral study in the dog (lambda- cyhalothrin) LOAEL = 0.5 based on gait abnormalities observed in 2 dogs.
21-Day dermal toxicity study in the rat (lambda-cyhalothrin) LOAEL = 50 mg/kg/day based on clinical signs of neurotoxicity (observed from day 2) and decreased body weight and body weight gain
21-Day inhalation study in rats (lambda-cyhalothrin) LOAEL = 3.3 [mu]g/L (0.90 mg/kg/day) based on clinical signs of neurotoxicity, decreased body weight gains, increased incidence of punctuate foci in the cornea, slight reductions in cholesterol in females and slight changes in selected urinalysis parameters.
In a developmental toxicity study in rats, the maternal NOAEL was 10 mg/kg/day and the LOAEL was 15 mg/kg/day based on uncoordiniated limbs, reduced body weight gain and food consumption. The developmental NOAEL was 15 mg/kg/day, highest dose tested (HDT) and the developmental LOAEL was >15 mg/kg/day.

Reproductive toxicity study. In a 3-generation reproduction study in rats, the parental/offspring NOAEL was 1.5 mg/kg/day and the LOAEL was 5.0 mg/kg/day based on decreased parental body weight and body weight gain during premating and gestation periods and reduced pup weight and weight gain during lactation. The reproductive NOAEL was 5.0 mg/kg/day (HDT)

Nov 27, 2002 OPP-2002-0313

EPA approved the use of lambda-Cyhalothrin for 3 Emergency Exemption.

-- Louisiana: EPA authorized the use of lambda-cyhalothrin on sugarcane to control sugarcane borers; July 12, 2002 to September 15, 2002.
-- Minnesota: Specific: EPA authorized the use of lambda-cyhalothrin on wild rice to control rice worms; July 25, 2002 to September 10, 2002.
-- Montana: Specific: EPA authorized the use of lambda-cyhalothrin on
barley to control the Russian wheat aphid and the cereal leaf beetle; June 24, 2002 to July 30, 2002.

Sept 27, 2002 OPP-2002-0204

SYNGENTA. Pesticide Tolerances. FINAL RULE.
EPA's decision to grant several tolerances needs to be read. EPA states: "The cyhalothrins induce clinical signs of neurotoxicity in at least three species (rats, mice and dogs), and a developmental neurotoxicity (DNT) study has been required. A subchronic neurotoxicity study has recently been submitted but has not yet been reviewed; a preliminary review found that the NOAELs are higher than endpoints selected by EPA and this study is not expected to change conclusions of this risk assessment.
EPA has required that a DNT be conducted for lambda-cyhalothrin based upon structure activity relationship (SAR), mode of action, and toxicity information that identifies cyhalothrin and lambda-cyhalothrin as neurotoxic pesticides. Developmental neurotoxicity testing with cyhalothrin is required, to further characterize the potential hazard to the developing animal, in accordance with standard OPP guidance. This determination was based upon a weight-of-evidence evaluation of the database..."

Tolerance for residues of the insecticide lambda- cyhalothrin, in or on
Commodity Approved Petitioned
Almond, hulls 1.5 ppm - 
Apple pomace, wet 2.50 ppm - 
Avocados (imported) 0.20 ppm - 

Canola

1.0 ppm

PP 0F06092 proposed a tolerance for canola seed of 0.15 ppm, subsequently revised in this final rule to 1.0 ppm on canola and 2.0 ppm in canola oil.

Canola, oil 2.0 ppm - see above
Cereal grain crop group (except rice and wild rice), grain,   at 0.2 ppm - unacceptable at this time since additional residue field trial data are necessary in support of these tolerances
Fruit, pome, group 0.30 ppm - 
Fruit, stone, group 0.50 ppm - 
Nut, tree, group 0.05 ppm - 
Pea and bean, dried shelled,(except soybean), subgroup 0.10 ppm - 
Pea and bean, succulent shelled, subgroup 0.01 ppm - 
Peanut, hay 3.0 ppm - 
Sorghum, grain, forage 0.30 ppm - 
Sugarcane 0.05 ppm existing tolerances for the section 18 emergency exemption under Sec. 180.438(b) for sugarcane at 0.03 ppm is not needed since a tolerance is established by this regulation rule
Tomatoes -  at 0.1 ppm is no longer needed. It is being replaced with the new tolerance for the vegetables, fruiting, group (except cucurbits) at 0.2 ppm
Vegetables, fruiting, group (except cucurbits) 0.20 ppm -
Vegetables, legume, edible podded, subgroup 0.20 ppm - 
August 7, 2002 OPP-2002-0164

Emergency Exemptions for pesticide use.

-- Colorado Department of Agriculture - EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids; May 8, 2002 to July 15, 2002.

-- Idaho Department of Agriculture - EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids; May 22, 2002 to July 30, 2002.

-- Montana Department of Agriculture - EPA authorized the use of lambda-cyhalothrin on barley to control cutworms; May 22, 2002 to July 1, 2002.

-- Wyoming Department of Agriculture - Specific: EPA authorized the use of lambda-cyhalothrin on barley to control Russian wheat aphids; May 22, 2002 to July 31, 2002.

May 17, 2002 OPP-2002-0037 Revocation of Expired Time Limited Tolerances. FINAL RULE.
Time-limited tolerances for canola seed and flax seed are being removed from 40 CFR 180.438 because they expired on December 31, 2000.
Nov 14, 2001 OPP-181082

Pesticide Emergency Exemptions. EPA authorized use in:

-- Colorado: on barley to control the Russian wheat aphid; April 15, 2001 to July 15, 2001.

-- Idaho: on barley to control Russian wheat aphids and cereal leaf beetles; May 2, 2001 to July 30, 2001.

-- Louisiana: on sugarcane to control sugarcane borers; June 15, 2001 to September 15, 2001.

-- Montana: on barley to control cutworms; March 20, 2001 to July 1, 2001.

-- Montana: on barley to control the Russian wheat aphid; May 1, 2001 to July 30, 2001.

-- Wyoming: on barley to control Russian wheat aphids; May 2, 2001 to July 31, 2001.

Dec 20, 2000 OPP-181078

Pesticide Emergency Exemptions.

-- Colorado, EPA authorized use on barley to control the Russian wheat aphid; 5/1/00 to 7/30/00.

-- Louisiana, EPA authorized use on sugarcane to control the sugarcane borer; 7/5/00 to 9/15/00.

-- Montana, the Dept. of Agriculture, on 5/11/00, use on barley to control the Russian wheat aphid. This program ended on 7/30/00.

-- Montana, EPA authorized use of on barley to control cutworms; 3/7/00 to 7/1/00.

-- Montana, EPA authorized use on barley to control the Russian wheat aphid; 5/11/00 to 7/30/00.

-- Wyoming, EPA authorized use on barley to control the Russian wheat aphid; 5/10/00 to 7/31/00.

Jan 29, 1999 OPP-300780 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE.
This regulation establishes a time-limited tolerance for the combined residues of lambda-cyhalothrin and its epimer in or on flax seed 0.1 ppm;, barley bran 0.2 ppm; barley grain 0.05 ppm; barley hay and barley straw 2 ppm; canola seed 0.1 ppm; and sugarcane 0.03 ppm. These tolerances will expire and are revoked on December 31, 2000.
Feb 13, 1998 OPP-300608

ZENECA - Petition for Pesticide Tolerances.- FINAL RULE.
This regulation establishes tolerances for the combined residues of the pyrethroid lambda-cyhalothrin and its epimer in or on alfalfa forage at 5.0 ppm; alfalfa hay at 6.0 ppm; leaf lettuce at 2.0 ppm; brassica head and stem subgroup (broccoli, Chinese broccoli, Brussels sprouts, cabbage, Chinese (napa) cabbage, Chinese mustard, cauliflower, caval broccolo, and kohlrabi) at 0.4 ppm; replaces the term ``grain dust'' with ``aspirated grain fractions'' with a tolerance of 2.0 ppm; and increases the tolerance for poultry fat from 0.01 ppm to 0.03 ppm.

Dec 3, 1997 na Correction to Pesticide Tolerance.
Nov 26, 1997 OPP-300581

ZENECA - Petition for Pesticide Tolerances. - FINAL RULE.
This regulation establishes tolerances for the combined residues of the pyrethroid lambda-cyhalothrin and its epimer in or on broccoli, cabbage, corn (grain, fodder and forage), corn (sweet), cottonseed, dry bulb onion, garlic, lettuce, head, peanuts, rice, soybeans, sorghum, sunflower, tomatoes, wheat, sunflower, and livestock commodities. It also removes time limitations for tolerances for residues of lambda-cyhalothrin on the same commodities that expire on November 15, 1997.

Oct 29, 1997 OPP-300555 Pesticide Tolerances for Emergency Exemptions. - FINAL RULE.
This regulation establishes time-limited tolerances for combined residues of lambda-cyhalothrin and its epimer in or on barley grain, barley bran, barley hay and straw, canola seed, and sugarcane. This action is in response to EPA's granting of emergency exemptions under section 18 of the Federal Insecticide, Fungicide, and Rodenticide Act authorizing use of the pesticide on BARLEY: bran at 0.2 ppm, grain at 0.05 ppm, hay and straw at 2 ppm; canola seed at 0.1 ppm; sugarcane at 0.03 ppm; in Louisiana and Montana. Revocation Date for these exemptions is august 30, 1998.
Oct 8, 1997 PF-769

ZENECA - Pesticide Tolerance Petition; for residues for residues of the insecticide lambda-cyhalothrin and its epimer in or on the raw agricultural commodities avocados (imported) at 0.2 ppm; cereal grain crop group (except rice and wild rice): grain, 0.2 ppm, forage (except sorghum) 6.0 ppm, hay 2.0 ppm, straw 2.0 ppm, aspirated grain dust 2.0 ppm, bran 0.8 ppm and flour 0.6 ppm; fruiting vegetable crop group (except cucurbits) 0.2 ppm; peas and beans - edible podded crop subgroup 0.2 ppm; peas and beans - succulent shelled crop subgroup 0.01 ppm; peas and beans - dried shelled subgroup (except soybean) 0.1 ppm; peanut hay 3.0 ppm; sorghum forage 0.3 ppm; sorghum fodder 0.5 ppm; and sugarcane 0.05 ppm.

Sept 25, 1997 PF-767

BAYER - Petition to remove the time limitations on the established tolerances for residues of lambda-cyhalothrin and its epimer in or on the following crops and commodities:

Crop Tolerance Crop Tolerance Crop Tolerance
alfalfa, forage 5.0 ppm cottonseed 1.0 ppm horses, fat 1.0 ppm
alfalfa, hay 10.0 ppm cottonseed, oil 2.0 ppm horses, meat 0.4 ppm
aspirated grain fractions 300 ppm cottonseed, hulls 2.0 ppm horses, meat by-prod. 0.4 ppm
carrotts 0.2 ppm citrus, whole fruit 0.2 ppm milkfat 15.0 ppm
cattle, fat 1.0 ppm citrus oil 0.3 ppm peppers 0.5 ppm
cattle, meat 0.4 ppm citrus dried pulp 0.3 ppm poultry, fat 0.01 ppm
cattle, meat by-products 0.4 ppm eggs 0.01 ppm poultry, meat 0.01 ppm
corn, forage (sweet) 15.0 ppm goats, fat 1.0 ppm poultry, meat by-products 0.01 ppm
corn, fodder (sweet) 30 ppm goats, meat 0.4 ppm radishes 1.0 ppm
corn (sweet, K+CWHR) 0.05 ppm goats, meat by-products 0.4 ppm sheep, fat 1.0 ppm
sheep, meat 0.4 ppm sorghum, forage 2.0 ppm sunflower, seed 0.02 ppm
sheep, meat by-prod. 0.4 ppm sorghum, grain 4.0 ppm sugarcane 0.05 ppm
sorghum, fodder 5.0 ppm suflower, forage 1.0 ppm sugarcane, molasses 0.2 ppm
tomatoes 0.2 ppm tomato, concentrated products 0.5 ppm tomato, pomace
(wet and dry)
5.0 ppm
August 4, 1997 OPP-300523 Pesticides Subject to Tolerance Reassessment.
July 11, 1997 PF-748

ZENECA - Pesticide Petition Filing. To establish a tolerance for combined residues of the insecticide lambda-cyhalothrin and its epimer in or on the raw agricultural commodities alfalfa forage at 5.0 ppm, alfalfa hay at 6.0 ppm, leaf lettuce at 2.0 ppm, head and stem Brassica crop subgroup at 0.4 ppm, aspirated grain fractions at 2.0 ppm and increasing the existing time-limited tolerance for poultry fat to 0.03 ppm.

July 9, 1997 OPP-300509 Time-Limited Pesticide Tolerance. - FINAL RULE.
This regulation establishes a time-limited tolerance for the combined residues of lambda-cyhalothrin and its epimer in or on RICE: Grain AT 1 PPM; Straw AT 1.8 PPM; Hulls AT 5 PPM.
Feb 19, 1997 PF-699

ZENECA - Pesticide Tolerance Petition; for residues of lambda-cyhalothrin and its epimer in or on the raw agricultural commodities rice grain at 1 ppm, rice straw at 1.75 ppm, and in or on the processed commodity rice hulls at 5.0 ppm.

Dec 13, 1995 PF-636

ZENECA - Petition for Pesticide Tolerances: lettuce, leaf at 2.0 ppm; head and stem brassica crop subgroup (broccoli; broccoli, Chinese; brussels sprouts; cabbage; cabbage, Chinese (napa); cabbage, Chinese mustard; cauliflower; caval broccolo; and kohlrabi) at 0.4 ppm; alfalfa, forage at 3.0 ppm; and alfalfa, hay at 4.0 ppm.

July 5, 1995 PP 1F3992,
2F4109,
2F4114,
7F3488,
7F3560,
9F3770,
FAP 7H3560,
and 7H5543/ R2143

ZENECA and COOPERS - Pesticide Tolerances for residues in or on the raw agricultural commodities soybeans; wheat, forage, hay, straw, and grain dust; sweet corn; sunflower, seeds and forage; sorghum grain and dust; corn (grain, field and pop); corn fodder and forage; peanuts; meat, fat, and meat byproducts (mbyp) and eggs of poultry. - FINAL RULE.

April 28, 1995 1F3992,
2F4109,
2F4114,
7F3488,
7F3560,
9F3770,
FAP 7H3560 and 7H5543/P615

ZENECA and COOPERS - Petition to establish time-limited tolerances with an expiration date of Nov 15, 1997, for residues in or on the raw agricultural commodities soybeans, wheat, forage, hay, straw, grain dust; sweet corn; sunflower, seeds and forage; sorghum grain and dust; corn (grain field and pop); corn fodder and forage; peanuts; meat, fat, and meat byproducts (mbyp) and eggs of poultry and increase tolerances in milk, fat, meat and mbyp of cattle, goats, hogs, horses and sheep; and in or on the processed food/feed items corn grain flour, sunflower hulls, sunflower oil, and wheat bran.

March 27, 1995 na

ZENECA (formerly ICI) - Petition for Pesticide Tolerances.- FINAL RULE.
This rule establishes tolerances for residues in or on the raw agricultural commodities tomatoes, cabbage, broccoli, head lettuce, dry bulb onion, and garlic and in or on the processed food/feed tomato pomaces.

Feb 22, 1995 na Pesticide Tolerances. US EPA amends and extends tolerances for the synthetic pyrethroids with an expiration date of November 15, 1997, to cover residues expected to result from use during the period of conditional registration.- FINAL RULE.
Nov 14, 1994 na Pesticide Tolerance Extension Petition.
The US EPA is proposing to amend/extend the tolerances on cottonseed and other commodities with an expiration date of November 15, 1997, to cover residues expected to result from use during the period of conditional registration.

 

 
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