Reports
available from
The National Technical Information Service
(NTIS)
Order from NTIS by: phone at 1-800-553-NTIS (U.S. customers);
(703)605-6000 (other countries); fax at (703)605-6900; and
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Road, Springfield, VA, 22161, USA. |
| Order
No. |
Title |
Abstract |
NTIS/00400217
22p |
2003
- Re-evaluation of hydramethylnon.
Pest
Management Regulatory Agency. Alternative Strategies &
Regulatory Affairs Division, Ottawa (Ontario).
Proposed
acceptability for continuing registration no. PACR2003-11.
Text in English and French (Bilingual). French ed. on
the same fiche. |
Hydramethylnon
is an insecticide used to kill cockroaches or ants in
domestic applications. This report provides a rationale
for the decision concerning the re-evaluation of hydramethylnon
and provides information on proposed modifications to
labels and additional data requirements.
Keywords:
Insecticides
Cockroaches
Ants
Modifications
Decisions
Pesticides
Regulation
Foreign technology
*Hydramathylnon
*Bilingual |
NTIS/PB99-121287
168p
•
Available for free online |
1998
- Reregistration Eligibility Decision (RED): Hydramethylnon.
(Includes RED Facts: Hydramethylnon Fact Sheet).
Environmental
Protection Agency, Washington, DC. Office of Prevention,
Pesticides and Toxic Substances. |
The
U.S. Environmental Protection Agency has completed its
reregistration eligibility decision of the pesticide active
ingredient tetrahydro-5,5- dimentyl-2(1H)-pyrimi dinone(3-(4-(trifluo
romethyl)phenyl)-1- (2-(4-(trifluoromethyl) phenyl)ethenyl)-2-
propenylidine)hydrazone, also known as hydramethylnon.
The document presents the Agency's decision regarding
the reregistration eligibility of the registered usesof
hydramethylnon. Section I is the introduction. Section
II describes hydramethylnon, its uses, data requirements,
and regulatory history. Section III discusses the human
health and environmental assessment based on the data
available to the Agency. Section IV presents the reregistration
decision for hydramethylnon. Section V discusses the reregistration
requirements for hydramethylnon. And, Section VI containsthe
Appendices which support this Reregistration Eligibility
Decision documents. For Fact Sheet only see also PB99-121204.
|
NTIS/PB99-121204
6p
•
Available
for free online |
1998
- RED Facts: Hydramethylnon.
Environmental
Protection Agency, Washington, DC. Office of Prevention,
Pesticides and Toxic Substances. |
This
fact sheet summarizes the information in the RED document
for reregistration case 2585, hydroamethylnon. Hydramethylnon
is an insecticide used to control ants, cockroaches, crickets,
and termites. There are 28 end use product formulations
that are either granular baits or ready-to-use gelatin.
The use on rangelands or pastures primarily for Imported
Fire ant control, is considered to be a food use and established
tolerances are cited in 40 CFR Section 180.395. Fact sheet.
See also PB99-121287. |
NTIS/OTS0539184
EPA/OTS;
Doc #88-920002121
Keywords: |
1991
- INITIAL SUBMISSION: HYDRAMETHYLNON: STUDY TO DETERMINE
THE N-OCTANOL OR WATER PARTITION COEFFICIENT WITH COVER
LETTER DATED 12-26-91 |
AMER
CYANAMID INC
HYDRAMETHYLNON
ENVIRONMENTAL FATE
PHYSICAL/CHEMICAL PROPERTIES
PARTITION COEFFICIENT
CAS Registry Numbers: 67485-29-4 |
NTIS/PB83-231472
8p |
1983
- Cell Death and Inhibition of Population Growth of Marine
Unicellular Algae by Pesticides.
Authors:
Walsh GE
Environmental
Research Lab., Gulf Breeze, FL. |
The
marine diatom, Skeletonema costatum, was exposed to the
pesticides hexachlorocyclopentadiene, EPN, chlorpyrifos,
carbophenothion, and Atrazine and examined for death of
cells with Evans blue, a mortal stain. All pesticides caused
death of cells, but significant mortality occurred at concentrations
greater than the EC50. The insecticide, Amdro, did not kill
the marine algae S. costatum, Thalassiosira pseudonana,
Isochrysis galbana, Chorella sp., or Dunaliella tertiolecta.
However, Amdro was very inhibitory to algal population growth
at low concentrations. Journal article, Pub. in Aquatic
Toxicology 3, p209-214 1983.
Keywords:
Algae
Toxicity
Pesticides |
| NTIS/PB83-170365 |
1982
- Mirex,
Fire Ants, and Estuaries
Lowe JI
Environmental
Research Lab., Gulf Breeze, FL. |
The
insecticide mirex was used for 16 years (1962-1978) in
the Southeastern United States to control the imported
fire ant. During 1969-1971, a field monitoring study,
carried out in conjunction with an aerial application
of mirex to coastal areas in South Carolina, revealed
that mirex was translocated from treated lands and high
marsh to estuarine biota. All uses
of mirex were cancelled in 1978. A new insecticide named
Amdro [hydramethylnon] was
conditionally approved for control of fire ants by the
Environmental Protection Agency in August 1980. |
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6732007&dopt=Abstract
Am J Vet
Res 1984 May;45(5):1023-7
Hematologic
and immunologic responses of Holstein calves to a fire ant toxicant.
Evans DL, Jacobsen KL, Miller
DM.
Holstein calves (3 to 5 months of age) were used to develop
an animal model sensitive to environmental toxicants. In the
present study, the fire ant toxicant AMDRO
was fed (113.5 g/day/calf) to weanling castrated calves (9 test
and 9 controls) for 7 weeks. As early as 14 days after the start
of the AMDRO feeding, leukopenia
was observed. Differential counts revealed significant non-transient
decreases in lymphocytes and eosinophils.
Eosinopenia was observed from days 21
to 49 of AMDRO treatment. Variability
in hematocrit and hemoglobin values in treated and control calves
precluded making a determination of trends due to toxicant exposure.
The AMDRO treatment did not produce significant decreases in
primary or secondary antibody responses to keyhole limpet hemocyanin
or to Brucella abortus vaccination. It also did not produce
suppression of cellular immunity, as determined by delayed-type
hypersensitivity response to bacille Calmette-Guerin. Potential
effects of AMDRO on thermoregulatory mechanisms were indicated
by significant depressions of rectal temperature observed after
25, 32, and 39 days' treatment.
PMID: 6732007 [PubMed - indexed for MEDLINE]
Note
from FAN:
Leukopenia definition: a decrease in the
absolute White Blood Cell count
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11721517&dopt=Abstract
Pest Manag
Sci 2001 Nov;57(11):1011-6
An
oral bioassay for the toxicity of hydramethylnon to individual
workers and queens of Argentine ants, Linepithema humile.
Hooper-Bui LM, Rust MK.
Department of Entomology, University of California, Riverside,
CA 92521, USA. Lhooper@agctr.lsu.edu
We have developed an oral bioassay to determine the toxicity
of hydramethylnon to individual workers and queens of the Argentine
ant, Linepithema humile. We fed seven concentrations of hydramethylnon
in suspension to individual workers or queens, determined the
amount of hydramethylnon ingested and evaluated the individual
ants for mortality 14 days later. At concentrations > or
= 0.37 g liter-1, the amount of liquid the queens ingested decreased
dramatically, indicating that Argentine ant queens may detect
hydramethylnon. Significantly larger volumes of the two highest
concentrations of the hydramethylnon suspension were ingested
by the workers, compared to the lower concentrations, suggesting
that hydramethylnon may act as a feeding stimulant for the workers.
Worker mortality was higher than queen mortality at the highest
concentrations tested. The highest worker mortality resulted
when the ants ingested 1.03 micrograms of hydramethylnon per
mg of ant tissue. At the highest concentration
(1.0 g liter-1) tested, workers ingested almost 12 times as
much active ingredient per mg of body weight as did queens,
suggesting that, in order to increase mortality of queens, multiple
feedings must occur.
PMID: 11721517 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11681688&dopt=Abstract
J Econ Entomol
2001 Oct;94(5):1229-36
Transfer
of ingested
insecticides among cockroaches: effects of active ingredient,
bait formulation, and assay procedures.
Buczkowski G, Kopanic RJ Jr,
Schal C.
Department of Entomology, North Carolina State University, Raleigh
27695-7613, USA.
Foraging cockroaches ingest insecticide baits, translocate them,
and can cause mortality in untreated cockroaches that contact
the foragers or ingest their excretions. Translocation of eight
ingested baits by adult male Blattella germanica (L.) was examined
in relation to the type of the active ingredient, formulation,
and foraging area. Ingested boric acid, chlorpyrifos, fipronil,
and hydramethylnon that were excreted by adults in small dishes
killed 100% of first instars within 10 d and >50% of second
instars within 14 d. Residues from these ingested baits were
also highly effective on nymphs in larger arenas and killed
16-100% of the adults. However, when the baits and dead cockroaches
were removed from the large arenas and replaced with new cockroaches,
only residues of the slow-acting hydramethylnon killed most
of the nymphs and adults, whereas residues of fast acting insecticides
(chlorpyrifos and fipronil) killed fewer nymphs and adults.
Excretions from cockroaches that ingested abamectin baits failed
to cause significant mortality in cockroaches that contacted
the residues. These results suggest that hydramethylnon is highly
effective in these assays because cockroaches that feed on the
bait have ample time to return to their shelter and defecate
insecticide-laden feces. The relatively high concentration of
hydramethylnon in the bait (2.15%) and its apparent stability
in the digestive tract and feces probably contribute to the
efficacy of hydramethylnon. To control for differences among
baits in inert ingredients and the amount of active ingredient,
we compared 1% chlorpyrifos with 1% hydramethylnon in identical
baits. Again, hydramethylnon residues
provided greater secondary kill, but the results highlighted
the importance of the inert ingredients. We conclude
that, in the absence of cannibalism and necrophagy, translocation
of baits and secondary kill are most effective with slow acting
insecticides in palatable baits that can traverse the digestive
tract and be deposited within and around the cockroach aggregation.
PMID: 11681688 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11425024&dopt=Abstract
J Econ Entomol
2001 Jun;94(3):686-93
Attractiveness
of insecticide baits for cockroach control (Dictyoptera: Blattellidae):
laboratory and field studies.
Nalyanya G, Liang D, Kopanic
RJ Jr, Schal C.
Department of Entomology, North Carolina State University, Raleigh
27695-7613, USA.
Several insecticide bait formulations were evaluated for their
attractiveness to cockroaches in olfactometer assays in the
laboratory and in trapping experiments in the field. Included
in the assays were bait stations, gels, pastes, and a powder
that contained one of the following active ingredients: abamectin,
boric acid, chlorpyrifos, or hydramethylnon. There were significant
differences among the baits in their attractiveness to the German
cockroach, Blattella germanica (L.). In trapping experiments,
Avert powder (abamectin), Maxforce station
and gel, and Siege gel (all hydramethylnon) were consistently
attractive to B. germanica adults and nymphs. Laboratory olfactometer
assays with adult males confirmed these results and showed that
nymphs were as responsive as males whereas females
were less responsive. Our bioassays also demonstrate
that attractiveness of bait can be dramatically affected by
the age of the bait. One week of aging significantly reduced
the attractiveness of Avert powder in both laboratory and field
assays. Aging, however did not diminish the attractiveness of
Maxforce gel, indicating that the formulation may be critical
for retention of attractiveness of baits. Baits that were most
attractive to the German cockroach were also the most attractive
to nymphs and adults of the brownbanded cockroach, Supella longipalpa
(F.).
PMID: 11425024 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10902342&dopt=Abstract
J Econ Entomol
2000 Jun;93(3):858-64
Oral
toxicity of abamectin, boric acid, fipronil, and hydramethylnon
to laboratory
colonies of Argentine ants (Hymenoptera: Formicidae).
Hooper-Bui LM, Rust MK.
Department of Entomology, University of California,
Riverside 92521, USA.
Comprehensive laboratory baiting studies with
the 4 insecticides abamectin, boric acid, fipronil, and hydramethylnon
were conducted against Argentine ant, Linepithema humile (Mayr).
Serial dilutions of each insecticide prepared in a 25% sucrose
solution were provided for 24 h or 14 d to groups of workers
and queens. Sucrose-water baits containing 1 x 10(-5)% fipronil
and 0.1% hydramethylnon provided complete
mortality of L. humile workers baited for 24 h. Baits
containing 1 x 10(-4) and 1 x 10(-5)% fipronil provided 100%
kill of queens. In the continuous baiting, 0.5% boric acid,
1 x 10(-6)% fipronil, and 0.025% hydramethylnon
provided 100% mortality of workers. The queens and workers
provided baits containing 1 x 10(-5)% fipronil and 0.5% boric
acid all died within 14 d. Low concentrations of fipronil and
boric acid in sucrose may be promising candidates for Argentine
ant control.
PMID: 10902342 [PubMed - indexed for MEDLINE]
From
Toxline at Toxnet
PESTIC SCI;
37 (1). 1993. 73-77.
Phototransformation
of the insecticide hydramethylnon in aqueous systems.
CHAKRABORTY SK,
BHATTACHARYYA A, CHOWDHURY A
Pesticide
Residue Lab., Dep. Agric. Chem. and Soil Sci., Bidhan Chandra
Krishi Viswavidyalaya, Kalyani-641 235, Nadia, West Bengal,
India.
BIOSIS COPYRIGHT: BIOL ABS. Sunlight irradiation of hydramethylnon
in aqueous media of different pH values resulted in 80-94% transformation
within 10 h. The rate of disappearance of the insecticide was
affected marginally by the initial pH of the reaction medium.
After 10 h irradiation, eight photoproducts were formed. Three
products were isolated as pure crystalline substances and the
structures of two of these (I & III) were characterized
by mass and NMR spectroscopy. The reaction mechanisms involved
in the formation of photoproducts are discussed.
From
Toxline at Toxnet
AM J VET
RES; 45 (5). 1984. 1023-1027. [HEEP]
HEMATOLOGIC
AND IMMUNOLOGIC RESPONSES OF HOLSTEIN CALVES TO A FIRE ANT TOXICANT
EVANS
DL, JACOBSEN KL, MILLER DM
Abstract: HEEP COPYRIGHT: BIOL ABS. RRM COW AMDRO ANIMAL MODEL
LEUKOPENIA LYMPHOCYTOTOXICITY EOSINOPENIA THERMOREGULATION ENVIRONMENTAL
POLLUTION INSECTICIDE
CAS Registry Number: 67485-29-4 - Hydramethylnon
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