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Adverse
Effects
Abstracts
ACTIVITY:
Insecticide (pyrethroid)
CAS Name:
(2,3,5,6-tetrafluorophenyl)methyl (1R-trans)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Structure:
Adverse
Effects:
Bladder
Body Weight Decrease
Bone
Brain
Cholesterol
CNS
Dermal
Endocrine: Adrenal
Endocrine: Thyroid
Genotoxic
Kidney
Liver
Lung
Spleen
Tremors |
Environmental
Effects:
'Extremely
dangerous to fish and other aquatic life' |
Regulatory
Information
(only comprehensive for the US) |
US
EPA Registered: |
No |
Registered
use in
(includes only a limited list of countries)
|
Australia,
Netherlands, New Zealand, Philippines |
Other
Information |
Molecular
Formula: |
C15H12Cl2
F4 O2 |
Manufacturers: |
Bayer |
Other
Names: |
Baygon
Bayothrin
BAY NAK 4455
BAY NAK 4711
NAK 4455 |
Manufacture
site: |
GERMANY:
Bayer, Bayerwerk Wuppertal, Leverkusen
|
Of
special interest: |
PAN
Data |
September
1997 - Evaluation
on: Transfluthrin Use as a Public Hygiene Insecticide.
Prepared by: the UK Health and Safety
Executive, Biocides & Pesticides Assessment Unit, Magdalen
House, Stanley Precinct, Bootle, Merseyside L20 3QZ. Available
from: Department for Environment, Food and Rural Affairs, Pesticides
Safety Directorate, Mallard House, Kings Pool, 3 Peasholme Green,
York YO1 7PX. UK. Available
online at
http://www.pesticides.gov.uk/citizen/evaluations/evallist_alphabet.htm
|
June
2002 - In
Australia when Transfluthrin is used for the "Control of
insects in domestic premises"
no maximum
residue levels are required. Ref: June 2002. Table 5.
Uses of substances where maximum residue limits are not
necessary. Australian National Registration Authority for Agricultural
Veterinary Chemicals. The MRL Standard. Maximum residue limits
in food and animal feedstuff. http://www.nra.gov.au/residues/mrl5.pdf
|
TRANSFLUTHRIN
is a synthetic pyrethroid and
is used in preparations to control
crawling and flying insects in the household. Based
on the oral toxicity of the substance it has been included in
Schedule 6. Preparations containing 1 per cent or less of transfluthrin
have been exempted from poisons scheduling.
Ref: Australia INFORMATION BULLETIN. POISONS
LEGISLATION
CIRCULAR NO. 73. 21 June 1996. |
Insecticide
used in the "Repellent Lamp"used for personal protection
against mosquitoes in Dar es Salaam, Tanzania |
Bayer
Insecticide: Baygon All Insect Killer. -
"Dr. Bug" website. |
Abstracts |
October
2001 -
Glossary of Pesticide Chemicals
- A listing of pesticides subject to analysis
of residues in foods and feeds by the US Food and Drug Administration.
|
Research
into fluorinated pyrethroid alcohols: An episode in the
history of pyrethroid discovery.
Author: NAUMANN K
Author Address: Landwirtschaftszentrum Monheim, Bayer AG,
D-51368 Leverkusen, Germany.
Source: PESTICIDE SCIENCE; 52 (1). 1998.
3-20.
BIOSIS
COPYRIGHT: BIOL ABS. An account of pyrethroid research from
1975 to 1985 at Bayer AG is given. The exploitation of fluorine
chemistry for this purpose led to increased activity of
known 3-phenoxybenzyl pyrethroid esters and to the commercialization
of the broad-spectrum insecticide cyfluthrin, the particularly
tick-toxic flumethrin and the rapid-acting household insecticides
fenfluthrin and transfluthrin.
The last two constituted in 1976 a novel type of pyrethroid,
based on polyfluorinated benzyl alcohols, off the mainstream
of published pyrethroid research. Transfluthrin, the single
isomer (1R)trans-permethric acid ester of 2,3,5,6-tetrafluorobenzyl
alcohol has just been introduced to the market. The
history of its discovery and structure-activity data as
well as resistance considerations regarding cyfluthrin,
are presented.
|
June
14, 2001 - Implementation
of the Community Strategy for Endocrine Disruptors - a
range of substances suspected of interfering with the hormone
systems of humans and wildlife. Communication from the Commission
to the Council and the European Parliament. Commission of
the European Communities, Brussels COM (2001) 262 final.
This
document presents a "priority list of substances for
further evaluation of their role in endocrine disruption.
During 2000, a candidate list of 553 man-made substances and
9 synthetic/natural hormones has been identified."
Category included on the Endocrine Disruptor Liist: |
Synthetic
pyrethroids |
While
only the broad category "Synthetic pyrethroids" was
included in the Commission's list, it might be of some interest
to note that the following organofluorine pesticides are "Synthetic
pyrethroids:" Acrinathrin, Bifenthrin,
beta-Cyfluthrin, Cyhalothrin, gamma-Cyhalothrin, lambda-Cyhalothrin,
Fenfluthrin, Flucythrinate, Flufenprox, Flumethrin, Fluvalinate,
tau-Fluvalinate, Halfenprox, Protrifenbute, Silafluofen, Tefluthrin,
Transfluthrin |
|