Transfluthrin
CAS No. 118712-89-3

 
 

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Adverse Effects
Abstracts

ACTIVITY: Insecticide (pyrethroid)

CAS Name: (2,3,5,6-tetrafluorophenyl)methyl (1R-trans)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

Structure:

Adverse Effects:

Bladder
Body Weight Decrease
Bone
Brain
Cholesterol
CNS
Dermal
Endocrine: Adrenal
Endocrine: Thyroid
Genotoxic
Kidney
Liver
Lung
Spleen
Tremors

Environmental Effects:

'Extremely dangerous to fish and other aquatic life'

Regulatory Information
(only comprehensive for the US)
US EPA Registered: No
Registered use in
(includes only a limited list of countries)

Australia, Netherlands, New Zealand, Philippines 
Other Information
Molecular Formula: C15H12Cl2 F4 O2 
Manufacturers: Bayer 
Other Names: Baygon
Bayothrin
BAY NAK 4455
BAY NAK 4711
NAK 4455
 
Manufacture site:

GERMANY:
Bayer, Bayerwerk Wuppertal, Leverkusen
 

Of special interest:
PAN Data 
September 1997 - Evaluation on: Transfluthrin Use as a Public Hygiene Insecticide. Prepared by: the UK Health and Safety Executive, Biocides & Pesticides Assessment Unit, Magdalen House, Stanley Precinct, Bootle, Merseyside L20 3QZ. Available from: Department for Environment, Food and Rural Affairs, Pesticides Safety Directorate, Mallard House, Kings Pool, 3 Peasholme Green, York YO1 7PX. UK. Available online at
http://www.pesticides.gov.uk/citizen/evaluations/evallist_alphabet.htm
June 2002 - In Australia when Transfluthrin is used for the "Control of insects in domestic premises" no maximum residue levels are required. Ref: June 2002. Table 5. Uses of substances where maximum residue limits are not necessary. Australian National Registration Authority for Agricultural Veterinary Chemicals. The MRL Standard. Maximum residue limits in food and animal feedstuff. http://www.nra.gov.au/residues/mrl5.pdf  
TRANSFLUTHRIN is a synthetic pyrethroid and is used in preparations to control crawling and flying insects in the household. Based on the oral toxicity of the substance it has been included in Schedule 6. Preparations containing 1 per cent or less of transfluthrin have been exempted from poisons scheduling.
Ref: Australia INFORMATION BULLETIN. POISONS LEGISLATION CIRCULAR NO. 73. 21 June 1996.
 
Insecticide used in the "Repellent Lamp"used for personal protection against mosquitoes in Dar es Salaam, Tanzania 
Bayer Insecticide: Baygon All Insect Killer. - "Dr. Bug" website. 
Abstracts 
October 2001 - Glossary of Pesticide Chemicals - A listing of pesticides subject to analysis of residues in foods and feeds by the US Food and Drug Administration.  

Research into fluorinated pyrethroid alcohols: An episode in the history of pyrethroid discovery.

Author: NAUMANN K

Author Address: Landwirtschaftszentrum Monheim, Bayer AG, D-51368 Leverkusen, Germany.

Source: PESTICIDE SCIENCE; 52 (1). 1998. 3-20.

BIOSIS COPYRIGHT: BIOL ABS. An account of pyrethroid research from 1975 to 1985 at Bayer AG is given. The exploitation of fluorine chemistry for this purpose led to increased activity of known 3-phenoxybenzyl pyrethroid esters and to the commercialization of the broad-spectrum insecticide cyfluthrin, the particularly tick-toxic flumethrin and the rapid-acting household insecticides fenfluthrin and transfluthrin. The last two constituted in 1976 a novel type of pyrethroid, based on polyfluorinated benzyl alcohols, off the mainstream of published pyrethroid research. Transfluthrin, the single isomer (1R)trans-permethric acid ester of 2,3,5,6-tetrafluorobenzyl alcohol has just been introduced to the market. The history of its discovery and structure-activity data as well as resistance considerations regarding cyfluthrin, are presented.


June 14, 2001 - Implementation of the Community Strategy for Endocrine Disruptors - a range of substances suspected of interfering with the hormone systems of humans and wildlife. Communication from the Commission to the Council and the European Parliament. Commission of the European Communities, Brussels COM (2001) 262 final.

This document presents a "priority list of substances for further evaluation of their role in endocrine disruption. During 2000, a candidate list of 553 man-made substances and 9 synthetic/natural hormones has been identified."
Category included on the Endocrine Disruptor Liist:

Synthetic pyrethroids While only the broad category "Synthetic pyrethroids" was included in the Commission's list, it might be of some interest to note that the following organofluorine pesticides are "Synthetic pyrethroids:" Acrinathrin, Bifenthrin, beta-Cyfluthrin, Cyhalothrin, gamma-Cyhalothrin, lambda-Cyhalothrin, Fenfluthrin, Flucythrinate, Flufenprox, Flumethrin, Fluvalinate, tau-Fluvalinate, Halfenprox, Protrifenbute, Silafluofen, Tefluthrin, Transfluthrin
 
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