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Sex-Specific Neurotoxic Effects of Early-Life Exposure to Fluoride: a Review of the Epidemiologic and Animal Literature.
References Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance U.S. Department of Health and Human Services Federal Panel on Community Water Fluoridation. U.S. public health service recommendation for fluoride concentration in drinking water for the prevention of dental caries. Public Health Rep. 2015;130(1):1–14 Available from: http://www.publichealthreports.org/fluorideguidelines.cfm. […]
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Fluoride balance in infants and young children in the UK and its clinical relevance for the dental team.
Key Points Provides an overview of the main sources of fluoride in children. Stresses the proportion of fluoride (F) intake from ingestion of toothpaste. Draws attention to the implications for oral health of the F balance in infants and young children. Illustrates the importance of assessing fluoride exposure at an individual and community level […]
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NTP Study: “Fluoride is presumed to be a cognitive neurodevelopmental hazard to humans”
The Fluoride Action Network has published the press release below. Please email the PR Newswire version of our release to you local decision makers and the news editors of the media outlets in your community, large and small (newspaper, radio, TV, online). On Oct 22, the National Toxicology Program (NTP) published a draft review of fluoride’s neurotoxicity […]
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Fluoride contamination in and around selected geothermal sites in Odisha, Eastern India: assessment of ionic relations, fluoride exposure and remediation
Abstract Fluoride contamination in groundwater is a major problem throughout the world as well as in India. High-fluoride content was reported in the hot springs of Atri and Tarbalo sites in Odisha, India, and residents of nearby villages showed the manifestations of fluorosis. Around 39% of the groundwater samples showed fluoride concentration > 1 mg/l, […]
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Aloe vera protects against fluoride-induced teratogenic effects during pre- and postnatal development in mice.
References Aboubakr M, Elbadawy M, Soliman A, Hewaity M (2014) Embryotoxic and teratogenic effect of norfloxacin in female albino rats. Adv Pharmacol Pharmaceutical Sci 2014:1–6. https://doi.org/10.1155/2014/924706 CAS Article Google Scholar Anuradha CD, Kanno S, Hirano S (2001) Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60cells. Free Rad […]
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Poor groundwater quality and high potential health risks in the Datong Basin, northern China: research from published data
Abstract Datong Basin in China is a typical arid-semiarid inland basin, with high levels and wide distributions of arsenic (As), fluoride (F–), and iodine (I). To better understand the presence of low-quality groundwater in Datong Basin and assess the health risks for local residents, groundwater samples were collected from the shallow aquifer and in medium-deep […]
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A holistic study on fluoride-contaminated groundwater models and its widespread effects in healthcare and irrigation
Abstract Groundwater is a key resource in the world. Its importance is often undermined, despite the various applications which include irrigation, drinking, sanitation, and industrial uses. One of the contaminants of groundwater is fluoride or the fluorine ion. Fluoride is a common pollutant of water, carrying potential benefits and costs to various sectors. Fluoride contamination […]
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Groundwater fluoride concentrations in the watershed sedimentary basin of Quetta Valley, Pakistan
Abstract Litho-geochemical characteristics of low and high fluoride (F–) groundwater along with hydrological processes were investigated to delineate its genesis and enrichment mechanism in a watershed sedimentary basin. In this study, groundwater F– concentration ranged from 0 to 20 mg/L with a mean and standard deviation of 2.8 and ± 3.7 mg/L, respectively. Out of […]
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Effect of Sodium Fluoride on Reproductive Function Through Regulating Reproductive Hormone Level and Circulating SIRT1 in Female Rats.
References Kabir H, Gupta AK, Tripathy S (2020) Fluoride and human health: systematic appraisal of sources, exposures, metabolism, and toxicity. Crit Rev Env Sci Tec 50(11):1116–1193. https://doi.org/10.1080/10643389.2019.1647028 CAS Article Google Scholar Choubisa SL (2015) Industrial fluorosis in domestic goats (Capra hircus), Rajasthan. India Fluoride 48(2):105–112 CAS Google Scholar Szczuko M, Splinter J, Zapalowska-Chwyc M, Zietek […]
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Exposure to Fluoride induces apoptosis in liver of ducks by regulating Cyt-C/Caspase 3/9 signaling pathway.
Highlights Long-term exposure NaF induced hepatotoxicity in ducks. NaF exposure caused liver granule and vacuolar degeneration observed by histological analysis. The mechanism of NaF exposure on hepatotoxicity involving activating autophagy and apoptosis. Cyt-C/Caspase 3/9 signaling pathway activation target cell death. Abstract Fluorine being a well-known and essential element for normal physiological functions of tissues of […]