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A Systematic Review and Meta-Analysis of the Relationship Between the Severity of Dental Fluorosis and Fluoride Biomarkers in Endemic Areas.
References Wei W, Pang S, Sun D (2019) The pathogenesis of endemic fluorosis: Research progress in the last 5 years. J Cell Mol Med 23:2333–2342. https://doi.org/10.1111/jcmm.14185 CAS Article PubMed PubMed Central Google Scholar Patil MM, Lakhkar BB, Patil SS (2018) Curse of Fluorosis. Indian J Pediatr 85:375–383. https://doi.org/10.1007/s12098-017-2574-z CAS Article PubMed Google Scholar Kurdi MS […]
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Fluoride in Drinking Water, Diet, and Urine in Relation to Bone Mineral Density and Fracture Incidence in Postmenopausal Women.
Exposure to fluoride occurs mainly through drinking water, which may include fluoride from natural sources and fluoride added to prevent tooth decay. Naturally occurring fluoride concentrations can vary substantially, from insignificant to well above the World Health Organization (WHO)-recommended limit of 1.5mg/L (WHO 2006), whereas the concentration in artificially fluoridated water is typically around 0.7mg/L […]
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Level of fluoride and arsenic in household shallow well water in Wamiao and Xinhuai villages in Jiangsu Province, China
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Topical fluoride as a cause of dental fluorosis in children.
Plain language summary Is the use of fluoride toothpaste during early childhood associated with discolouration/mottling of teeth? There is strong evidence that the use of toothpaste containing fluoride can prevent tooth decay (caries) in both children and adults. However, a possible adverse effect associated with the use of fluoride toothpaste is the mottling of permanent […]
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Environmental exposures and pediatric kidney function and disease: A systematic review.
Two studies investigated the association of fluoride exposure, including 1 cross-sectional and 1 case-control. In a cross-sectional study of fluoride exposure in 210 children in China, the investigators found increases of urine NAG and urine ?-GT levels (Liu et al., 2005). In case-control study of fluoride levels in 210 children in China, slightly higher urine […]
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WITHDRAWN: Community-based population-level interventions for promoting child oral health.
Discussion Summary of main results This review includes 38 studies of community-based population-level interventions for promoting child oral health, with a total of 119,789 children. Interventions were generally implemented for less than one year (n = 26), and about half (n = 11) of studies were randomised controlled trials. Investigators tested a variety of oral […]
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A Benchmark Dose Analysis for Maternal Pregnancy Urine-Fluoride and IQ in Children.
Discussion … The increased precision using the average maternal U-F concentration as an indicator of prenatal fluoride exposure results in stronger statistical evidence of fluoride-associated deficits, compared with using cross-sectional or retrospective studies. Still, the amount of fluoride that reaches the brain during early brain development is unknown, and even the maternal U-F concentration measurements […]
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Human cultured IMR-32 neuronal-like and U87 glial-like cells have different patterns of toxicity under fluoride exposure.
When comparing the F-induced toxicity on neurons and glial cells, it is important to highlight that most studies have used neurons and only two have investigate de glial cells behavior after F exposure [21, 36]. The effect of F on neuronal cell viability is inconsistent across the studies with doses ranging from 18.09 ?g/mL to […]
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Histological and chemical studies in man on effects of fluoride
Comparison of fluoride content in the soft tissues of persons meeting the criteria of exposure to fluoride with the content in soft tissues of persons not meeting the criteria revealed no significant difference (P > 0.05). This finding indicates that fluoride is not stored in the soft tissues in significant quantities (table 3). The fluoride […]
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Impact of Pharmacological Interventions in Expectant Mothers Resulting in Altered Mutans Streptococci Levels in their Children.
… The efficacy of postnatal interventions in expectant mothers for preventing dental caries and MS transmission in their children has been thoroughly studied18; however, data regarding the efficacy of prenatal interventions remain unclear. Therefore, the purpose of this paper was to provide a systematic review of the current literature assessing the efficacy of maternal administration […]