PESTICIDE

ADVERSE EFFECTS

REGISTERED FOR USE

• CAS No. 2164-17-2

• Herbicide (Urea)

• Adverse Effects:
• Ataxia
• Blood
• Body Weight Decrease
• Bone
• Brain
• Cancer: Possible Human Carcinogen:
  LUNG, LYMPHOCYTIC LYMPHOMAS
  CNS
• Endocrine: Pituitary
• Endocrine: Testicular
• Eye
• Kidney
• Leukemia
• Liver
• Lung
• Reproductive/Developmental
• Spleen

Environmental:

• Groundwater pollutant. The significant cancer risk contributors have been identified as drinking water (all sources).

• Acute risks to birds, mammals, and endangered species.

• In its March 2005 reassessment, EPA noted that several key studies regarding risks to animals and fish have not been submitted by the registrant, Makhteshim-Agan.

• Registered use in: Australia, India, US,
  Africa: Burkina Faso, Cape Verde, Chad, Gambia, Guinea-Bissau, Mali, Mauritania, Niger, Senegal, South Africa, Tanzania

• See US tolerances

• Note: As of March 2005: Several new tolerances are being proposed; also, US EPA wants to increase existing tolerances.

• CAS No. 239110-15-7

• Fungicide

• Boby weight decrease
• Bone
• Decreased crown-rump length in fetuses
• Kidney
• Liver

• US:
  — imported grape
  — imported grape, raisin

• CAS No. 658066-35-4

• Fungicide

• CAS No. 1306-05-4

• Solid diluent, carrier

• Atrophic rhinitis
• Lung

Environmental:

• Abnormally high fluoride values were found in the phosphate-polluted sediments in the Jordan Gulf of Aqaba (Red Sea).

•  Nuaru: intensive phosphate mining during the past 90 years has left the central 90% of Nauru a wasteland and threatens limited remaining land resources

Contamination Incident:

• Placentia Bay, Newfoundland (1969)

• EPA Inert (new as of April 28, 2004)

• Registered use in: US – Because this is an “Inert”, the public is not allowed to know which crops it is used on.

• CAS No. 405-30-1

• Insecticide,Acaricide
  (bridged Diphenyl)

• CAS No. 47000-92-0

• Plant Growth
  Regulator

• CAS No. 38827-31-5

• Plant Growth
  Regulator

• CAS No. 640-19-7

• Insecticide,
  Rodenticide
  (Unclassified)

• PAN BAD ACTOR
  (acute toxicity)

• Ataxia
• Body Weight Loss (Anorexia, Emaciation)
• Brain
• CNS
• Endocrine: Testicular
• Fetotoxic
• Genotoxic
• Heart
• Kidney
• Reproductive toxicant

Environmental / Contamination:

• 2005. Amnesty International calls on Israel to halt poisoning of Palestinian livestock.

• 1979 paper: 800 dogs died shortly after consuming purchased poultry meat.

• 1969: poisoning in a dairy herd grazing fields adjacent to a chemical factory which manufactured fluoroacetamide.

• Registered use in: Belgium, Brazil, Congo, Denmark, Ethiopia, Finland, Greece, Iceland, Ireland, Israel, Spain, Sweden, Togo, UK, Venezuela

• Illegal to import into 101 countries 

• CAS No. 144-49-0

• Rodenticide
  (Unclassified)

• Ataxia
• Brain
• CNS
• Endocrine: Testes
• Heart
• Kidney
• Spinal Cord

• Also known as Flurochloridone

• CAS No. 61213-25-0

• Herbicide
  (Unclassified)

• Reproductive

• Registered use in: France, Germany, Hungary, Portugal, South Africa

• CAS No. 61213-59-0

• CAS No. 15457-05-3

• Herbicide
  (Nitrophenyl ether)

• WHO: believed
  obsolete or
  discontinued

• Genotoxic potential

Environmental:

• Highly toxic to fish

• US Tolerances: Revoked

• European Commission: Not allowed to be used as an active ingredient after July 25, 2003

• CAS No. 77501-60-1

• Herbicide
  (Nitrophenyl ether)

• Registered in: Germany, Hungary
  

• European Commission: Not allowed to be used as an active ingredient after July 25, 2003.However, it is not clear whether the EU banned Fluoroglycofen or Fluoroglycofen-ethyl.

• CAS No. 77501-90-7

• Herbicide
  (Nitrophenyl ether)

• Ataxia
• Blood
• Body Weight Decrease
• Bone
• Embryotoxic / Fetotoxic – rabbits only
• Kidney
• Liver

• Registered in: Netherlands, South Africa, UK

• European Commission: Not allowed to be used as an active ingredient after July 25, 2003.

• However, it is not clear whether the EU banned Fluoroglycofen or Fluoroglycofen-ethyl.

• CAS No. 41205-21-4

• Fungicide
  (Pyrrole)

• Registered use in: Japan

• CAS No. 13577-71-4

• Herbicide
  (Unclassified)

• WHO: believed
  obsolete or
  discontinued

• CAS No. 13738-63-1

• Herbicide
  (Nitrophenyl ether)

• (Fluorophene)

• CAS No. 4776-06-1

• Molluscicide

Note from FAN:
Both bromine and fluorine are in the chemical formula for this substance. Studies on its effect on the brain need to be performed. (EC)

• EPA uses this name:
  Siloxanes and silicones, 
  Me 3,3,3-trifluoropropyl

• CAS No. 63148-56-1

• EPA List 3 Inert

• List 3 Inert

• Registered use in US
  – Because this is an “Inert”, the public is not allowed to know which crops it is used on.

• CAS No. 51-21-8

• Former insect
  Chemosterilant –
  now used as a chemotherapeutic drug

• Prop 65:
  Developmental
  Toxicity

• Anemia
• Ataxia
• Blood
• Bone Brain 
• Developmental Toxicant
• Embryotoxic
• Endocrine: Gonadotoxicity / Spermatogenesis
• Endocrine: Ovary
• Endocrine: Thymus
• Gastrointestinal tract
• Genotoxic
• Heart
• Lung
• Teratogen
• Urinary Tract

• CAS No. 16961-83-4

• Wood Preservative

• Bone
• Dermal
• Eye
• Gastrointestinal tract

• Banned in Austria

• CAS No. 33439-45-1

• Herbicide
  (Phenylurea)

• CAS No. 31251-03-3

• Fungicide (Triazole)

• WHO: believed
  obsolete or
  discontinued

• CAS No. 361377-29-9
  and
  CAS No. 193740-76-0

• Fungicide
  (Strobin)

• New pesticide in April 2002.

See effects

• Body Weight
• Bone
• Decrease
• Endocrine: Adrenal
• Endocrine: Testicular
• Endocrine: Thyroid
• Endocrine: Uterus
• Kidney
• Liver 
• Reproductive
• Spleen
• Urinary tract

Environmental:
• Moderately to highly persistent in soil.
• Moderately toxic to estuarine/marine fish.
• Highly toxic to freshwater fish and invertebrates.
• Very highly toxic to estuarine/marine invertebrates.
• Risks to endangered/threatened freshwater fish species.

• On Sept 16, 2005, EPA approved over 100 tolerances for the first-time use of fluoxastrobin on food in the US. These tolerances include milk, meat, and vegetables.