NTP 2021: The 2nd NASEM Peer Review
Released February 9, 2021:
The second peer-review by the National Academies of Sciences, Engineering, and Medicine (NASEM) of NTP’s second draft is titled: Revised Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Letter Report.
NASEM also released a News Release concurrently with the release of its peer-review.
In its peer-review, the NASEM committee wrote:
… It is important to note that the committee did not conduct its own independent evaluation of the evidence, nor did it conduct a data audit; both were outside its scope.
… The monograph needs to emphasize that much of the evidence presented comes from studies that involve relatively high fluoride concentrations, and to make clear that the monograph cannot be used to draw conclusions about low fluoride exposure concentrations (less than 1.5 mg/mL), including those in fluoridated drinking water systems…
Chris Neurath, the Science Director of the Fluoride Action Network, presented a poster in 2020 titled, Fluoride Developmental Neurotoxicity: Dose-Response Analyses of Recent High Quality Studies, at a conference of the International Society for Environmental Epidemiology (ISEE). Neurath noted:
Of the 29 human fluoride studies that the NTP classified as higher quality, 27 found neurotoxic effects.
Of those finding adverse effects: 18 were at fluoride levels below 1.5 mg/L and 13 at levels below 0.7 mg/L.
Neurath has demonstrated that with NTP’s own data, the high-quality studies finding loss of IQ at exposures below 1.5 mg/L are just as consistent and numerous as those above 1.5 mg/L. Over 90% of the low-dose studies found loss of IQ.
See the NTP’s immediate reaction to NASEM’s peer review here
Documents and News Reports leading up to, and including, 2021
|Sept 6, 2019||NTP||The NTP’s first Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|March 5, 2020||NAS||The NASEM’s first peer review of the Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|Sept 16, 2020||NTP||The NTP’s revised (second) Draft Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
|NEURATH: DOSE RESPONSE DOCUMENTS:
• FAN dose-response assessment of Nov. 30, 2020
• Appendix which provides the computer code used to generate the meta-analyses and meta-regressions
• Data file in Excel format.xlsx”
• Updated ISEE 2020 Conference poster
• Supporting details for dose-response analysis summaries shown in ISEE 2020 Conference poster
• A zip file for:
Dose response analysis
Meta-analysis data high quality NTP studies
|Feb 9, 2021||NAS||The NASEM’s second peer-review of the revised (second) Draft NTP Monograph on the Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Letter Report.
|Feb 9 2021||NAS||News Release from the National Academies of Sciences, Engineering and Medicine.
|Feb 11, 2021||ADA||By Jennifer Garvin. National Academies ’strongly recommends’ third revision to fluoride monograph. ADA News (American Dental Association).
|Feb 11, 2021||AFS||Press Release. National Academies rejects the NTP draft report about fluoride. American Fluoridation Society.
|Feb 16, 2021||FAN||Press Release. According to Fluoride Action Network, the NAS strengthens findings on fluoride’s neurotoxicity. Fluoride Action Network.