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Research Studies
Study Tracker

Study Tracker

The most up-to-date and comprehensive source for studies on fluoride's multifaceted effects on human and animal health, with 100+ years of research organized by health category, type of study, author, journal, and date.
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MiR-1a-3p Inhibits Apoptosis in Fluoride-exposed LS8 Cells by Targeting Map3k1.

October 2, 2023 | Biological Trace Element Research | Chen T, Gu Y, Bai G-H, Liu X, Chen B, Fan Q, Liu J-G, Tian Y. |
Introduction Endemic fluorosis is a chemical disease that affects people all over the world. It is also one of the most serious diseases that naturally occur in China. Dental fluorosis is a precursor and specific indicator of chronic fluorosis in the oral cavity and has a significant impact around the world. When dental fluorosis develops, it not only changes how a person looks but can also affect their mental health in different ways. According to the results of the fourth oral epidemi

Fluoride-induced apoptosis in non-skeletal tissues of experimental animals: A systematic review and meta-analysis.

July 28, 2023 | Heliyon | Angwa LM, Nyadanu SD, Kanyugo AM, Adampah T, Pereira G. | 9(8):E18646.
1. Introduction ... Apoptosis is a highly regulated and programmed cell death characterized by specific biochemical and morphological features that culminate in cellular shrinkage to apoptotic bodies that are engulfed by neighboring macrophages [[12]]. This occurs without an accompanying inflammatory response. Characterized morphological changes accompanying apoptosis include cleavage of cytoskeletal filament fibers, cell cytoplasm, and nucleus condense, DNA fragmentation by the action of end