Abstract
Cretinism in iodine-deficiency areas is well known, yet the milder forms of somatic and psychomotor maldevelopment and thyroid dysfunction caused by iodine deficiency may be more difficult to detect. DeQuervain, in 1936, called this milder form “semi-cretinism,” while in 1980 Laggasse used the term “cretinoidism.” It was formally named “subclinical endemic cretinism” at a symposium on subclinical cretinism held in Xinzhou, Shanxi province in 1985. Currently, attention is being focused on these disorders in China and abroad. The Hetian prefecture in Xinjiang has reportedly been one of the Asian areas most severely affected by iodine deficiency disorders (IDD). During the period 1987-1989, we made a systematic survey of subclinical endemic cretinism in this district under a UNICEF aid Project.
Published by the Xinjiang Institute for Endemic Disease Control and Research; Office of Leading Group for Endemic Disease Control of Hetian Prefectural Committee of the Communist Party of China; and County Health and Epidemic Prevention Station, Yutian, Xinjiang.
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Research on the effects of fluoride on child intellectual development under different environmental conditions.
Goal: To study the effects of the fluoride and iodine content of drinking water on child intellectual development and the interaction between the two factors and also the relationship of educational factors to such development. Methods: The subjects of the investigation were 8- to 14-year-old children randomly selected from endemic areas as well
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The effects of high levels of fluoride and iodine on intellectual ability and the metabolism of fluoride and iodine.
The authors carried out a study on the intellectual abilities and fluoride/iodine metabolism of children living in a high fluoride-high iodine area. Among the results: the percentage of the general population living in this fluoride/iodine-contaminated region that suffered from goiter (clinical thyroid enlargement) was 3.8%, the rate of children already showing some thyroid
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Iodine Status Modifies the Association between Fluoride Exposure in Pregnancy and Preschool Boys’ Intelligence
In animal studies, the combination of in utero fluoride exposure and low iodine has greater negative effects on offspring learning and memory than either alone, but this has not been studied in children. We evaluated whether the maternal urinary iodine concentration (MUIC) modifies the association between maternal urinary fluoride (MUF)
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Effects of high iodine and high fluorine on children’s intelligence and thyroid function.
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The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.
Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to
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