Abstract
The study contains the results of fluoride testing done on 31 fetal specimens. It demonstrates that fluoride can pass through the placenta into the fetus, that bone tissues shows the highest levels of fluoride while brain tissue shows the lowest, and that overall level of fluoride increases with the fluoride burden of the mother and the age of the fetus.
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Fluoridation and the occurrence of Down's syndrome
The prevalence rates of Down's syndrome at birth were compared for Massachusetts residents ingesting fluoridated and non-fluoridated water. The observations included nearly all children born alive with Down's syndrome in Massachusetts during the 17-year period 1950-1966. A rate of 1.5 cases per 1000 births was found for fluoride-related births and
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Developmental toxicity evaluation of sodium fluoride administered to rats and rabbits in drinking water.
Sodium fluoride (NaF; Cas No. 7681-49-4) is used in fluoridating municipal water supplies, resulting in chronic exposure of millions of people worldwide. Because of a lack of pertinent developmental toxicity studies in the literature, sodium fluoride was administered ad libitum in deionized/filtered drinking water (to mimic human exposure) to Sprague-Dawley-derived
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Intake and metabolism of fluoride
The purpose of this paper is to discuss the major factors that determine the body burden of inorganic fluoride. Fluoride intake 25 or more years ago was determined mainly by measurement of the concentration of the ion in the drinking water supply. This is not necessarily true today because of
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Urticaria due to fluorides
Six cases of urticaria are reported in which trace quantities of fluoride proved to have played a major etiological role. The causative relationship was established by blindfold tests, by the history and by the concomittant symptomatology. Following an oral test dose of fluoride given to five of the six cases
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Enamel uptake and patient exposure to fluoride: comparison of APF gel and foam
This crossover study with 46 child dental patients compared two topical APF products, a gel and a foam, with respect to the amounts of product and fluoride (F) applied, salivary F concentrations, and enamel F uptake. Half the subjects were treated for 4 min with the gel first and the
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