Abstract
Goal: Determine the dose-response relationship between tea-induced osteofluorosis and brick tea intake.
Method: In two representative tea-induced fluorosis areas in the north and south of China, namely Aba County of Sichuan province and Chen Banner of Inner Mongolia Autonomous Region, osteofluorosis suffers were diagnosed by means of x-ray and a regression analysis was conducted to investigate sufferers fluoride intake from brick tea.
Result: In Aba County, level 1, 2, and 3 osteofluorosis sufferers have an average daily intake of fluoride from drinking brick tea of 6.26, 9.92, and 12.80 mg, respectively. In Chen banner, level 1 and level 2 osteofluorosis sufferers have a daily intake of fluoride from drinking brick tea of 6.26 and 10.23 mg, respectively; no level 3 sufferers were found. A linear relationship exists between disease severity and annual brick tea consumption (F = 330.23, p < 0.01), with a correlation coefficient of 0.77.
Conclusion: A dose-response relationship exists between the severity of osteofluorosis and the intake of fluoride from tea drinking.
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Fluorosis as a probable factor in metabolic bone disease in captive New Zealand native frogs (Leiopelma species)
This report describes the investigations into the cause and treatment of metabolic bone disease (MBD) in captive native New Zealand frogs (Leiopelma spp.) and the role of fluoride in the disease. MBD was diagnosed in Leiopelma archeyi and Leiopelma hochstetteri in 2008 at three institutions: Auckland Zoo, Hamilton Zoo, and
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A case of bone fluorosis of undetermined origin
After predominant theories on the causes of fluorosis are described and remarks made about the metabolism of fluoride, an observation of bone fluorosis in a 64-year-old patient is reported. Because, despite painstaking research, none of the known causes of bone fluorosis could be found in our patient, a new pathomechanism is being offered for discussion, i.e.,
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Correlation of fluoride in drinking water with urine, blood plasma, and serum fluoride levels of people consuming high and low fluoride drinking water in Pakistan
A case-controlled study has compared urinary, blood plasma, and serum fluoride (F) levels of people living in endemic areas of the Thar Desert, Sindh, Pakistan, consuming groundwater with F concentrations as high as 4.00–10.00 mg/L with those consuming groundwater with low F levels of 0.30 mg/L. A total of 121
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An epidemiological study of skeletal fluorosis in some villages of Chandrapur District, Maharashtra, India
Fluorosis is an important public health problem in certain parts of India. Chandrapur is one of the fluorosis endemic district of Maharashtra. An investigation was undertaken in three villages of study area to assess the clinical symptoms of skeletal fluorosis and in turn to find out the severity of the
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Endemic Fluorosis in the Nellore District of South India.
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