Abstract
Goal: Determine the dose-response relationship between tea-induced osteofluorosis and brick tea intake.
Method: In two representative tea-induced fluorosis areas in the north and south of China, namely Aba County of Sichuan province and Chen Banner of Inner Mongolia Autonomous Region, osteofluorosis suffers were diagnosed by means of x-ray and a regression analysis was conducted to investigate sufferers fluoride intake from brick tea.
Result: In Aba County, level 1, 2, and 3 osteofluorosis sufferers have an average daily intake of fluoride from drinking brick tea of 6.26, 9.92, and 12.80 mg, respectively. In Chen banner, level 1 and level 2 osteofluorosis sufferers have a daily intake of fluoride from drinking brick tea of 6.26 and 10.23 mg, respectively; no level 3 sufferers were found. A linear relationship exists between disease severity and annual brick tea consumption (F = 330.23, p < 0.01), with a correlation coefficient of 0.77.
Conclusion: A dose-response relationship exists between the severity of osteofluorosis and the intake of fluoride from tea drinking.
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The impact of fluoride in drinking water on oral health and skeletal system of school children
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Industrial fluorosis [Franke et al.]
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Fluoride-related bone disease associated with habitual tea consumption
Acquired osteosclerosis is a rare disorder of bone formation but an important consideration in adults with sclerotic bones or elevated bone density results. In such patients, malignancy, hepatitis C, and fluorosis should all be considered when making a diagnosis. We describe 4 patients evaluated at our Metabolic Bone Disease Clinic
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Serum osteocalcin and calcitonin in adult males with different fluoride exposures
The concentrations of serum osteocalcin (OCN) and calcitonin (CTN) were determined in sixty male workers exposed to fluoride (F) at an aluminum plant in Danjiang city, and in thirty non-F exposed males of the same general age from the local market town Gaolou village of Jun county in Danjiang city
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Clinical aspects of fluorosis in horses
Horses grazing in areas where cattle and sheep had developed severe fluorosis were examined clinically. Of those examined, 12 horses of different ages and with various degrees of fluorosis were selected for necropsy. Selected tissues were examined grossly, histologically, and radiographically. Major fluorotic lesions occurred only when the horses ingested
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