The present research report has looked into the correlation between male infertility and the fluoride level in water, the occurrence of dental and skeletal fluorosis, [the volume and quality of] semen and the amount of fluoride contained therein. Results have shown that fluoride might be a leading cause of male infertility in regions with endemic fluorosis.
The influence of excess fluorine intake in the drinking water on reproductive efficiency in bovines
Observations were made over four breeding seasons to determine the effect of excessive intake of fluorine in the drinking water on the breeding efficiency of cattle. Fifty Afrikaner heifers, maintained under ordinary ranching conditions, were divided into five groups which received 5, 8 and 12 ppm fluorine respectively in the drinking
Effect of Sodium Fluoride on Reproductive Function Through Regulating Reproductive Hormone Level and Circulating SIRT1 in Female Rats.
Fluorosis causes female reproductive dysfunction with reduced fertility without established pathogenesis. To clarify the mechanism, Sprague–Dawley female rats were selected with drinking water containing 0, 50 (low), 100 (moderate), and 150 mg/L (high) sodium fluoride (NaF) for a short (2 months), medium (4 months), and long term (6 months). The water consumption and body
[Fluorosis of coal burning affects the male reproductive system].
Fluorosis of coal burning is a new type of endemic fluorosis in China, which affects the male reproductive system. Furthermore, the content of fluoride in the semen, sperm mortality, sperm concentration and the incidence of infertility are higher in severe fluorosis areas than in mild- and non-fluorosis areas, so are
Developmental toxicity of sodium fluoride measured during multiple generations
Sodium fluoride (NaF) has been used to fluoridate drinking water in the United States since the mid 1940s. Because of the lack of reliable studies on the multigeneration effects of the compound, NaF (0, 25, 100, 175 or 250 ppm in drinking water) was given to rats continuously during three
Fluoride impairs oocyte maturation and subsequent embryonic development in mice
The damage caused by fluorosis is permanent, and has been recognized as a public health problem in a number of regions of the world. Although multiple studies provided evidence that sodium fluoride (NaF) elicits adverse effects on reproductive function, the effect of fluoride on female germ cell development is not well understood. Therefore, the
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