Abstract
Sixty- five patients in Xinjiang with syndrome of endemic arsenism and fluorosis (SEAF) were investigated clinically from March 1982 to August 1989. SEAF is a kind of chronic syndrome resulting from the combined, harmful effects of two trace elements, arsenic and fluorine. Peripheral neuritis and cardiovascular changes were observed in this syndrome more often than in simple arsenism or simple fluorosis. The excessive quantities of these two trace elements in blood might have a synergic, harmful effect on the nervous and circulatory systems. No definite conclusion could be reached with regard to the morbidity of skin and visceral tumors in this series. The incidence of associated skin cancer was found to be 7.7% and an associated Grade II squamous cell carcinoma of the esophagus was encountered in one patient.
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On the Physiological and Medicinal Action of Hydrofluoric Acid and the Fluorides.
EXCERPTS: General Summary. 1. On account of the corrosive action of these substances on glass vessels their use in ordinary therapeutics seems beset by many difficulties. But by attending to a few precautions these obstacles can be so minimized as to be practically overcome. 2. The topical action of strong hydrofluoric acid differs
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Indoor air quality and health: Empirical evidence from fluoride pollution in China.
Highlights Burning high-fluoride-content coal indoors is the primary source of fluoride pollution in Guizhou Province of China. We apply individual fixed effect models to examine the effects of whether households use coal as domestic fuel. Fluoride pollution from coal burning significantly increases the blood pressure levels and the likelihood of
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ITRAQ-based proteomics reveals the potential mechanism of fluoride-induced myocardial contraction function damage.
Highlights Pressure-volume loop analysis highlighted the impaired effects of fluoride exposure on cardiac function and myocardial contraction indicators. Histological analysis of rat heart tissue under fluoride exposure revealed extensive damage. Proteomics analysis highlighted effects on the myocardial contraction pathway. Protein network analysis highlighted the key roles of RyRs, Tpm and
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Effects of chronic ingestion of sodium fluoride on myocardium in a second generation of rats
Possible effects of long term exposure (6 months) to sodium fluoride (NaF) through drinking water on the morphology and biochemistry of myocardial tissue in second generation adult male rats were investigated. Wistar strain female and male rats were reared until the second generation of rats obtained, during which they were
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Effect of fluoride on the respiration rate of rat cardiac mitochondria.
Fluoride by modifying the activity of mitochondrial enzymes may change their respiration rate. In this study NaF at concentrations 5, 10, and 50 µM had no effect on the State 3 respiration rate of rat cardiac mitochondria with succinate substrate. At a higher concentration of 7.5 mM, a significant (p<0.001)
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Fluoride, Blood Pressure and Hypertension
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Fluoride & Electrocardiogram Abnormalities
An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems
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Fluoride & Arteriosclerosis
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Fluoride & Myocardial Damage
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Fluoride & Arterial Calcification
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