Abstract
In the city of Antigo, Wisconsin, fluoridation of the public water supplies was initiated in 1949. ·It was discontinued in November 1960, and reinstituted in October 1965, A striking increase in the rate of deaths from heart disease occurred. in Antigo hnmediately following the introduction of fluoridation in 1949 and following its resumption in 1965. This trend was also evident when the death rates from heart disease in Antigo were compared with those of the United States as a whole. Among older individuals, the rise in mortality after initiation of fluoridation was much higher than among younger people.
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Analysis of x-ray heart areas of 30 patients with endemic fluorosis
I. Targets and methods Based on diagnosis standards formulated at the 1981 Shijiazhuang National Prevention of Endemic Fluorosis Meeting, 30 patients were chosen, 15 men and 15 women with an average age of 45, average height of 1.63 meters, and average weight of 54 kilograms, and all with clinical diagnoses
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Mechanism of fluoride action on the L-type calcium channel in cardiac ventricular myocytes.
The modulatory actions of fluoride on the function of the dihydropyridine-sensitive (L-type) Ca2+ channel were studied in rabbit cardiac myocytes. In cell-attached voltage-clamp experiments, using barium as the charge carrier, fluoride increased the activity of the Ca2+ channel dose-dependently. Low concentrations (<10 mM) of fluoride increased the number of traces
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Histological and chemical studies in man on effects of fluoride
The presence of elevated concentrations of fluorides in the atmosphere has been associated with changes in certain plants and an increase in the fluoride content of forage in certain areas in Utah. Long-term ingestion of such forage by some animals has produced changes characteristic of fluorosis in some of them.
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Electrocardiogram analysis of patients with skeletal fluorosis
To investigate the degree of myocardial damage resulting from endemic fluorosis, electrocardiograms of 136 skeletal fluorosis patients from an endemic fluorosis area were compared with electrocardiograms of a control group of 40 normal patients from a non-endemic fluorosis area. The results show that fluoride in drinking water consumed over time
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Oxidative indices correlate with dyslipidemia and pro-inflammatory cytokine levels in fluoride-exposed rats
The aim of this study was to establish the effects of fluoride on lipid metabolism and attendant inflammatory response by exposing rats to 50 mg L-1 and 100 mg L-1 of fluoride through drinking water for seven weeks. Both concentrations led to hypercholesterolemia while the 100 mg L-1 concentration induced
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Fluoride & Electrocardiogram Abnormalities
An electrocardiogram (ECG) is a diagnostic test that measures the electrical activity of the heart. An ECG can reveal heart rate, heart rhythym (i.e. steady or irregular), and the strength and timing of the heart’s natural electrical signals. ECGs are described in terms of “waves” (e.g. amplitude and duration). Problems
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Fluoride, Blood Pressure and Hypertension
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Fluoride & Arteriosclerosis
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Fluoride & Myocardial Damage
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Fluoride & Arterial Calcification
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